These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 11801601)

  • 1. Evidence for a model of agonist-induced activation of 5-hydroxytryptamine 2A serotonin receptors that involves the disruption of a strong ionic interaction between helices 3 and 6.
    Shapiro DA; Kristiansen K; Weiner DM; Kroeze WK; Roth BL
    J Biol Chem; 2002 Mar; 277(13):11441-9. PubMed ID: 11801601
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential modes of agonist binding to 5-hydroxytryptamine(2A) serotonin receptors revealed by mutation and molecular modeling of conserved residues in transmembrane region 5.
    Shapiro DA; Kristiansen K; Kroeze WK; Roth BL
    Mol Pharmacol; 2000 Nov; 58(5):877-86. PubMed ID: 11040033
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A highly conserved aspartic acid (Asp-155) anchors the terminal amine moiety of tryptamines and is involved in membrane targeting of the 5-HT(2A) serotonin receptor but does not participate in activation via a "salt-bridge disruption" mechanism.
    Kristiansen K; Kroeze WK; Willins DL; Gelber EI; Savage JE; Glennon RA; Roth BL
    J Pharmacol Exp Ther; 2000 Jun; 293(3):735-46. PubMed ID: 10869371
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Involvement of 5-HT(1B/1D) and 5-HT2A receptors in 5-HT-induced contraction of endothelium-denuded rabbit epicardial coronary arteries.
    Ellwood AJ; Curtis MJ
    Br J Pharmacol; 1997 Nov; 122(5):875-84. PubMed ID: 9384503
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Radiolabelling of the human 5-HT2A receptor with an agonist, a partial agonist and an antagonist: effects on apparent agonist affinities.
    Sleight AJ; Stam NJ; Mutel V; Vanderheyden PM
    Biochem Pharmacol; 1996 Jan; 51(1):71-6. PubMed ID: 8534270
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mapping the binding site pocket of the serotonin 5-Hydroxytryptamine2A receptor. Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin.
    Almaula N; Ebersole BJ; Zhang D; Weinstein H; Sealfon SC
    J Biol Chem; 1996 Jun; 271(25):14672-5. PubMed ID: 8663249
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of conserved aromatic residues essential for agonist binding and second messenger production at 5-hydroxytryptamine2A receptors.
    Roth BL; Shoham M; Choudhary MS; Khan N
    Mol Pharmacol; 1997 Aug; 52(2):259-66. PubMed ID: 9271348
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Paradoxical trafficking and regulation of 5-HT(2A) receptors by agonists and antagonists.
    Gray JA; Roth BL
    Brain Res Bull; 2001 Nov; 56(5):441-51. PubMed ID: 11750789
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of an endogenous 5-hydroxytryptamine2A receptor in NIH-3T3 cells: agonist-induced down-regulation involves decreases in receptor RNA and number.
    Saucier C; Albert PR
    J Neurochem; 1997 May; 68(5):1998-2011. PubMed ID: 9109526
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of two serine residues essential for agonist-induced 5-HT2A receptor desensitization.
    Gray JA; Compton-Toth BA; Roth BL
    Biochemistry; 2003 Sep; 42(36):10853-62. PubMed ID: 12962510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of constitutive 5-hydroxytryptamine(1B) receptor by a series of mutations in the BBXXB motif: positioning of the third intracellular loop distal junction and its G(o)alpha protein interactions.
    Pauwels PJ; Gouble A; Wurch T
    Biochem J; 1999 Oct; 343 Pt 2(Pt 2):435-42. PubMed ID: 10510311
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A unique phenotype of 5-HT2C, agonist-induced GTPgamma35S binding, transferable to 5-HT2A and 5-HT2B, upon swapping intracellular regions.
    Alberts GL; Chio CL; Im WB; Slightom JL
    Br J Pharmacol; 2003 Feb; 138(3):427-34. PubMed ID: 12569067
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Serotonin 5-hydroxytryptamine 2A receptor-coupled phospholipase C and phospholipase A2 signaling pathways have different receptor reserves.
    Kurrasch-Orbaugh DM; Watts VJ; Barker EL; Nichols DE
    J Pharmacol Exp Ther; 2003 Jan; 304(1):229-37. PubMed ID: 12490596
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multiple conformations of native and recombinant human 5-hydroxytryptamine(2a) receptors are labeled by agonists and discriminated by antagonists.
    López-Giménez JF; Villazón M; Brea J; Loza MI; Palacios JM; Mengod G; Vilaró MT
    Mol Pharmacol; 2001 Oct; 60(4):690-9. PubMed ID: 11562430
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular dynamics of 5-HT1A and 5-HT2A serotonin receptors with methylated buspirone analogues.
    Bronowska A; Chilmonczyk Z; Leś A; Edvardsen O; Ostensen R; Sylte I
    J Comput Aided Mol Des; 2001 Nov; 15(11):1005-23. PubMed ID: 11989622
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The third intracellular loop of the 5-hydroxytryptamine2A receptor determines effector coupling specificity.
    Oksenberg D; Havlik S; Peroutka SJ; Ashkenazi A
    J Neurochem; 1995 Apr; 64(4):1440-7. PubMed ID: 7891070
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Contribution of a helix 5 locus to selectivity of hallucinogenic and nonhallucinogenic ligands for the human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors: direct and indirect effects on ligand affinity mediated by the same locus.
    Almaula N; Ebersole BJ; Ballesteros JA; Weinstein H; Sealfon SC
    Mol Pharmacol; 1996 Jul; 50(1):34-42. PubMed ID: 8700116
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Site-directed mutagenesis of the serotonin 5-hydroxytrypamine2 receptor: identification of amino acids necessary for ligand binding and receptor activation.
    Wang CD; Gallaher TK; Shih JC
    Mol Pharmacol; 1993 Jun; 43(6):931-40. PubMed ID: 8316224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The dynamin-dependent, arrestin-independent internalization of 5-hydroxytryptamine 2A (5-HT2A) serotonin receptors reveals differential sorting of arrestins and 5-HT2A receptors during endocytosis.
    Bhatnagar A; Willins DL; Gray JA; Woods J; Benovic JL; Roth BL
    J Biol Chem; 2001 Mar; 276(11):8269-77. PubMed ID: 11069907
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells.
    Porter RH; Benwell KR; Lamb H; Malcolm CS; Allen NH; Revell DF; Adams DR; Sheardown MJ
    Br J Pharmacol; 1999 Sep; 128(1):13-20. PubMed ID: 10498829
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.