229 related articles for article (PubMed ID: 11801603)
1. SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP).
Vucic D; Deshayes K; Ackerly H; Pisabarro MT; Kadkhodayan S; Fairbrother WJ; Dixit VM
J Biol Chem; 2002 Apr; 277(14):12275-9. PubMed ID: 11801603
[TBL] [Abstract][Full Text] [Related]
2. Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.
Vucic D; Franklin MC; Wallweber HJ; Das K; Eckelman BP; Shin H; Elliott LO; Kadkhodayan S; Deshayes K; Salvesen GS; Fairbrother WJ
Biochem J; 2005 Jan; 385(Pt 1):11-20. PubMed ID: 15485396
[TBL] [Abstract][Full Text] [Related]
3. ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas.
Vucic D; Stennicke HR; Pisabarro MT; Salvesen GS; Dixit VM
Curr Biol; 2000 Nov; 10(21):1359-66. PubMed ID: 11084335
[TBL] [Abstract][Full Text] [Related]
4. Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9.
Davoodi J; Lin L; Kelly J; Liston P; MacKenzie AE
J Biol Chem; 2004 Sep; 279(39):40622-8. PubMed ID: 15280366
[TBL] [Abstract][Full Text] [Related]
5. Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs). A caspase-independent mechanism for apoptotic inhibition.
Wilkinson JC; Wilkinson AS; Scott FL; Csomos RA; Salvesen GS; Duckett CS
J Biol Chem; 2004 Dec; 279(49):51082-90. PubMed ID: 15371416
[TBL] [Abstract][Full Text] [Related]
6. Sequence requirements for Hid binding and apoptosis regulation in the baculovirus inhibitor of apoptosis Op-IAP. Hid binds Op-IAP in a manner similar to Smac binding of XIAP.
Wright CW; Clem RJ
J Biol Chem; 2002 Jan; 277(4):2454-62. PubMed ID: 11717313
[TBL] [Abstract][Full Text] [Related]
7. Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein.
Fu J; Jin Y; Arend LJ
J Biol Chem; 2003 Dec; 278(52):52660-72. PubMed ID: 14523016
[TBL] [Abstract][Full Text] [Related]
8. Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP).
Franklin MC; Kadkhodayan S; Ackerly H; Alexandru D; Distefano MD; Elliott LO; Flygare JA; Mausisa G; Okawa DC; Ong D; Vucic D; Deshayes K; Fairbrother WJ
Biochemistry; 2003 Jul; 42(27):8223-31. PubMed ID: 12846571
[TBL] [Abstract][Full Text] [Related]
9. Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells.
Yang QH; Du C
J Biol Chem; 2004 Apr; 279(17):16963-70. PubMed ID: 14960576
[TBL] [Abstract][Full Text] [Related]
10. Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway.
Srinivasula SM; Datta P; Fan XJ; Fernandes-Alnemri T; Huang Z; Alnemri ES
J Biol Chem; 2000 Nov; 275(46):36152-7. PubMed ID: 10950947
[TBL] [Abstract][Full Text] [Related]
11. A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO.
Hunter AM; Kottachchi D; Lewis J; Duckett CS; Korneluk RG; Liston P
J Biol Chem; 2003 Feb; 278(9):7494-9. PubMed ID: 12511567
[TBL] [Abstract][Full Text] [Related]
12. Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ.
Arnt CR; Chiorean MV; Heldebrant MP; Gores GJ; Kaufmann SH
J Biol Chem; 2002 Nov; 277(46):44236-43. PubMed ID: 12218061
[TBL] [Abstract][Full Text] [Related]
13. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO).
Ng CP; Bonavida B
Mol Cancer Ther; 2002 Oct; 1(12):1051-8. PubMed ID: 12481428
[TBL] [Abstract][Full Text] [Related]
14. Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases.
Samuel T; Welsh K; Lober T; Togo SH; Zapata JM; Reed JC
J Biol Chem; 2006 Jan; 281(2):1080-90. PubMed ID: 16282325
[TBL] [Abstract][Full Text] [Related]
15. Structural basis of IAP recognition by Smac/DIABLO.
Wu G; Chai J; Suber TL; Wu JW; Du C; Wang X; Shi Y
Nature; 2000 Dec 21-28; 408(6815):1008-12. PubMed ID: 11140638
[TBL] [Abstract][Full Text] [Related]
16. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.
Srinivasula SM; Hegde R; Saleh A; Datta P; Shiozaki E; Chai J; Lee RA; Robbins PD; Fernandes-Alnemri T; Shi Y; Alnemri ES
Nature; 2001 Mar; 410(6824):112-6. PubMed ID: 11242052
[TBL] [Abstract][Full Text] [Related]
17. The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9.
Qiu XB; Goldberg AL
J Biol Chem; 2005 Jan; 280(1):174-82. PubMed ID: 15507451
[TBL] [Abstract][Full Text] [Related]
18. A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells.
Bockbrader KM; Tan M; Sun Y
Oncogene; 2005 Nov; 24(49):7381-8. PubMed ID: 16044155
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
Zobel K; Wang L; Varfolomeev E; Franklin MC; Elliott LO; Wallweber HJ; Okawa DC; Flygare JA; Vucic D; Fairbrother WJ; Deshayes K
ACS Chem Biol; 2006 Sep; 1(8):525-33. PubMed ID: 17168540
[TBL] [Abstract][Full Text] [Related]
20. Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis.
Song Z; Yao X; Wu M
J Biol Chem; 2003 Jun; 278(25):23130-40. PubMed ID: 12660240
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]