101 related articles for article (PubMed ID: 11805219)
21. (9-[4-acetyl-3-hydroxy-2-n-propylphenoxy) methyl]-3-(1H-tetrazol-5-yl)-4H-pyrido [1,2-a] pyrimidin-4-one), AS-35, inhibits leukotriene synthesis.
Hamasaki Y; Zaitu M; Tsuji K; Miyazaki M; Hayasaki R; Muro E; Yamamoto S; Kobayashi I; Matsuo M; Ichimaru T; Miyazaki S
Int J Immunopharmacol; 2000 Jul; 22(7):483-90. PubMed ID: 10785545
[TBL] [Abstract][Full Text] [Related]
22. Modification of leukotriene A(4) hydrolase/aminopeptidase by sulfhydryl-blocking reagents: differential effects on dual enzyme activities by methyl-methane thiosulfonate.
Orning L; Fitzpatrick FA
Arch Biochem Biophys; 1999 Aug; 368(1):131-8. PubMed ID: 10415120
[TBL] [Abstract][Full Text] [Related]
23. Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors.
Calışkan B; Banoglu E
Expert Opin Drug Discov; 2013 Jan; 8(1):49-63. PubMed ID: 23095029
[TBL] [Abstract][Full Text] [Related]
24. Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Grice CA; Tays KL; Savall BM; Wei J; Butler CR; Axe FU; Bembenek SD; Fourie AM; Dunford PJ; Lundeen K; Coles F; Xue X; Riley JP; Williams KN; Karlsson L; Edwards JP
J Med Chem; 2008 Jul; 51(14):4150-69. PubMed ID: 18588282
[TBL] [Abstract][Full Text] [Related]
25. The leukotriene B
Deng B; Lin Y; Ma S; Zheng Y; Yang X; Li B; Yu W; Xu Q; Liu T; Hao C; He R; Ding F
Kidney Int; 2017 Jul; 92(1):89-100. PubMed ID: 28318626
[TBL] [Abstract][Full Text] [Related]
26. Purification and characterization of porcine skeletal muscle aminopeptidase T, a novel metallopeptidase homologous to leukotriene A4 hydrolase.
Sarker MA; Matsuda S; Mizutani O; Rao S; Migita K; Goto-Yamamoto N; Iefuji H; Nishimura T
Biosci Biotechnol Biochem; 2011; 75(6):1154-9. PubMed ID: 21670530
[TBL] [Abstract][Full Text] [Related]
27. Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.
Eccles W; Blevitt JM; Booker JN; Chrovian CC; Crawford S; de Leon AR; Deng X; Fourie AM; Grice CA; Herman K; Karlsson L; Kearney AM; Lee-Dutra A; Liang J; Luna R; Pippel D; Rao N; Riley JP; Santillán A; Savall B; Tanis VM; Xue X; Young AL
Bioorg Med Chem Lett; 2013 Feb; 23(3):811-5. PubMed ID: 23260350
[TBL] [Abstract][Full Text] [Related]
28. Leukotriene A(4)-hydrolase expression and leukotriene B(4) levels in chronic inflammation of bacterial origin: immunohistochemistry and reverse-phase high-performance liquid chromatography analysis of oral mucosal epithelium.
Eberhard J; Jepsen S; Tiemann M; Krause R; Açil Y; Albers HK
Virchows Arch; 2002 Jun; 440(6):627-34. PubMed ID: 12070603
[TBL] [Abstract][Full Text] [Related]
29. Development of selective tight-binding inhibitors of leukotriene A4 hydrolase.
Yuan W; Munoz B; Wong CH; Haeggström JZ; Wetterholm A; Samuelsson B
J Med Chem; 1993 Jan; 36(2):211-20. PubMed ID: 8423594
[TBL] [Abstract][Full Text] [Related]
30. Synthesis, docking, cytotoxicity, and LTA
El-Naggar MH; Mira A; Abdel Bar FM; Shimizu K; Amer MM; Badria FA
Bioorg Med Chem; 2017 Feb; 25(3):1277-1285. PubMed ID: 28065501
[TBL] [Abstract][Full Text] [Related]
31. Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation.
Thunnissen MM; Nordlund P; Haeggström JZ
Nat Struct Biol; 2001 Feb; 8(2):131-5. PubMed ID: 11175901
[TBL] [Abstract][Full Text] [Related]
32. A sensitive fluorigenic substrate for selective in vitro and in vivo assay of leukotriene A4 hydrolase activity.
Poras H; Duquesnoy S; Fournié-Zaluski MC; Ratinaud-Giraud C; Roques BP; Ouimet T
Anal Biochem; 2013 Oct; 441(2):152-61. PubMed ID: 23851339
[TBL] [Abstract][Full Text] [Related]
33. Formation of a novel enzymatic metabolite of leukotriene A4 in tissues of Xenopus laevis.
Strömberg F; Hamberg M; Rosenzvist U; Dahlén SE; Haeggström JZ
Eur J Biochem; 1996 Jun; 238(3):599-605. PubMed ID: 8706657
[TBL] [Abstract][Full Text] [Related]
34. Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase.
Penning TD; Chandrakumar NS; Desai BN; Djuric SW; Gasiecki AF; Malecha JW; Miyashiro JM; Russell MA; Askonas LJ; Gierse JK; Harding EI; Highkin MK; Kachur JF; Kim SH; Villani-Price D; Pyla EY; Ghoreishi-Haack NS; Smith WG
Bioorg Med Chem Lett; 2003 Mar; 13(6):1137-9. PubMed ID: 12643929
[TBL] [Abstract][Full Text] [Related]
35. Thermodynamic properties of leukotriene A
Wittmann SK; Kalinowsky L; Kramer JS; Bloecher R; Knapp S; Steinhilber D; Pogoryelov D; Proschak E; Heering J
Bioorg Med Chem; 2016 Nov; 24(21):5243-5248. PubMed ID: 27651294
[TBL] [Abstract][Full Text] [Related]
36. Structural characterization of the covalent attachment of leukotriene A3 to leukotriene A4 hydrolase.
Mancini JA; Waugh RJ; Thompson JA; Evans JF; Belley M; Zamboni R; Murphy RC
Arch Biochem Biophys; 1998 Jun; 354(1):117-24. PubMed ID: 9633605
[TBL] [Abstract][Full Text] [Related]
37. Leukotriene A4 hydrolase in the human lung. Inactivation of the enzyme with leukotriene A4 isomers.
Ohishi N; Izumi T; Minami M; Kitamura S; Seyama Y; Ohkawa S; Terao S; Yotsumoto H; Takaku F; Shimizu T
J Biol Chem; 1987 Jul; 262(21):10200-5. PubMed ID: 3038871
[TBL] [Abstract][Full Text] [Related]
38. Leukotriene A4 hydrolase: a critical role of glutamic acid-296 for the binding of bestatin.
Andberg M; Wetterholm A; Medina JF; Haeggström JZ
Biochem J; 2000 Feb; 345 Pt 3(Pt 3):621-5. PubMed ID: 10642521
[TBL] [Abstract][Full Text] [Related]
39. The development of novel LTA
Low CM; Akthar S; Patel DF; Löser S; Wong CT; Jackson PL; Blalock JE; Hare SA; Lloyd CM; Snelgrove RJ
Sci Rep; 2017 Mar; 7():44449. PubMed ID: 28303931
[TBL] [Abstract][Full Text] [Related]
40. Structure-based dissection of the active site chemistry of leukotriene A4 hydrolase: implications for M1 aminopeptidases and inhibitor design.
Tholander F; Muroya A; Roques BP; Fournié-Zaluski MC; Thunnissen MM; Haeggström JZ
Chem Biol; 2008 Sep; 15(9):920-9. PubMed ID: 18804029
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
