BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 11809708)

  • 1. Lack of WRN results in extensive deletion at nonhomologous joining ends.
    Oshima J; Huang S; Pae C; Campisi J; Schiestl RH
    Cancer Res; 2002 Jan; 62(2):547-51. PubMed ID: 11809708
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Loss of Werner syndrome protein function promotes aberrant mitotic recombination.
    Prince PR; Emond MJ; Monnat RJ
    Genes Dev; 2001 Apr; 15(8):933-8. PubMed ID: 11316787
    [TBL] [Abstract][Full Text] [Related]  

  • 3. WRN helicase expression in Werner syndrome cell lines.
    Moser MJ; Kamath-Loeb AS; Jacob JE; Bennett SE; Oshima J; Monnat RJ
    Nucleic Acids Res; 2000 Jan; 28(2):648-54. PubMed ID: 10606667
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Length-dependent degradation of single-stranded 3' ends by the Werner syndrome protein (WRN): implications for spatial orientation and coordinated 3' to 5' movement of its ATPase/helicase and exonuclease domains.
    Machwe A; Xiao L; Orren DK
    BMC Mol Biol; 2006 Feb; 7():6. PubMed ID: 16503984
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity.
    Brosh RM; von Kobbe C; Sommers JA; Karmakar P; Opresko PL; Piotrowski J; Dianova I; Dianov GL; Bohr VA
    EMBO J; 2001 Oct; 20(20):5791-801. PubMed ID: 11598021
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventions.
    Oshima J; Sidorova JM; Monnat RJ
    Ageing Res Rev; 2017 Jan; 33():105-114. PubMed ID: 26993153
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Homologous recombination resolution defect in werner syndrome.
    Saintigny Y; Makienko K; Swanson C; Emond MJ; Monnat RJ
    Mol Cell Biol; 2002 Oct; 22(20):6971-8. PubMed ID: 12242278
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of the human and mouse WRN 3'-->5' exonuclease.
    Huang S; Beresten S; Li B; Oshima J; Ellis NA; Campisi J
    Nucleic Acids Res; 2000 Jun; 28(12):2396-405. PubMed ID: 10871373
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A role for WRN in telomere-based DNA damage responses.
    Eller MS; Liao X; Liu S; Hanna K; Bäckvall H; Opresko PL; Bohr VA; Gilchrest BA
    Proc Natl Acad Sci U S A; 2006 Oct; 103(41):15073-8. PubMed ID: 17015833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA.
    Orren DK; Machwe A; Karmakar P; Piotrowski J; Cooper MP; Bohr VA
    Nucleic Acids Res; 2001 May; 29(9):1926-34. PubMed ID: 11328876
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The spectrum of WRN mutations in Werner syndrome patients.
    Huang S; Lee L; Hanson NB; Lenaerts C; Hoehn H; Poot M; Rubin CD; Chen DF; Yang CC; Juch H; Dorn T; Spiegel R; Oral EA; Abid M; Battisti C; Lucci-Cordisco E; Neri G; Steed EH; Kidd A; Isley W; Showalter D; Vittone JL; Konstantinow A; Ring J; Meyer P; Wenger SL; von Herbay A; Wollina U; Schuelke M; Huizenga CR; Leistritz DF; Martin GM; Mian IS; Oshima J
    Hum Mutat; 2006 Jun; 27(6):558-67. PubMed ID: 16673358
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A conserved and species-specific functional interaction between the Werner syndrome-like exonuclease atWEX and the Ku heterodimer in Arabidopsis.
    Li B; Conway N; Navarro S; Comai L; Comai L
    Nucleic Acids Res; 2005; 33(21):6861-7. PubMed ID: 16396834
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Homozygosity for the WRN Helicase-Inactivating Variant, R834C, does not confer a Werner syndrome clinical phenotype.
    Kamath-Loeb AS; Zavala-van Rankin DG; Flores-Morales J; Emond MJ; Sidorova JM; Carnevale A; Cárdenas-Cortés MD; Norwood TH; Monnat RJ; Loeb LA; Mercado-Celis GE
    Sci Rep; 2017 Mar; 7():44081. PubMed ID: 28276523
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA.
    Machwe A; Ganunis R; Bohr VA; Orren DK
    Nucleic Acids Res; 2000 Jul; 28(14):2762-70. PubMed ID: 10908333
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes From a Subset of Patients With Familial Colorectal Carcinomas.
    Arora S; Yan H; Cho I; Fan HY; Luo B; Gai X; Bodian DL; Vockley JG; Zhou Y; Handorf EA; Egleston BL; Andrake MD; Nicolas E; Serebriiskii IG; Yen TJ; Hall MJ; Golemis EA; Enders GH
    Gastroenterology; 2015 Dec; 149(7):1872-1883.e9. PubMed ID: 26344056
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells.
    Bacolla A; Wang G; Jain A; Chuzhanova NA; Cer RZ; Collins JR; Cooper DN; Bohr VA; Vasquez KM
    J Biol Chem; 2011 Mar; 286(12):10017-26. PubMed ID: 21285356
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Challenges for the Discovery of Non-Covalent WRN Helicase Inhibitors.
    Heuser A; Abdul Rahman W; Bechter E; Blank J; Buhr S; Erdmann D; Fontana P; Mermet-Meillon F; Meyerhofer M; Strang R; Schrapp M; Zimmermann C; Cortes-Cros M; Möbitz H; Hamon J
    ChemMedChem; 2024 Apr; 19(8):e202300613. PubMed ID: 38334957
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evidence for premature aging in a Drosophila model of Werner syndrome.
    Cassidy D; Epiney DG; Salameh C; Zhou LT; Salomon RN; Schirmer AE; McVey M; Bolterstein E
    Exp Gerontol; 2019 Nov; 127():110733. PubMed ID: 31518666
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Werner Syndrome and Diabetes: Opportunities for Precision Medicine.
    Kaylan KB; Philipson LH
    Diabetes Care; 2024 May; 47(5):785-786. PubMed ID: 38640412
    [No Abstract]   [Full Text] [Related]  

  • 20. POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis.
    Llorens-Agost M; Ensminger M; Le HP; Gawai A; Liu J; Cruz-García A; Bhetawal S; Wood RD; Heyer WD; Löbrich M
    Nat Cell Biol; 2021 Oct; 23(10):1095-1104. PubMed ID: 34616022
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.