BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

387 related articles for article (PubMed ID: 11814333)

  • 1. Kinetic and mechanistic analysis of the malonyl CoA:ACP transacylase from Streptomyces coelicolor indicates a single catalytically competent serine nucleophile at the active site.
    Szafranska AE; Hitchman TS; Cox RJ; Crosby J; Simpson TJ
    Biochemistry; 2002 Feb; 41(5):1421-7. PubMed ID: 11814333
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MCAT is not required for in vitro polyketide synthesis in a minimal actinorhodin polyketide synthase from Streptomyces coelicolor.
    Matharu AL; Cox RJ; Crosby J; Byrom KJ; Simpson TJ
    Chem Biol; 1998 Dec; 5(12):699-711. PubMed ID: 9862793
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Malonyl-CoA:ACP transacylase from Streptomyces coelicolor has two alternative catalytically active nucleophiles.
    Dreier J; Li Q; Khosla C
    Biochemistry; 2001 Oct; 40(41):12407-11. PubMed ID: 11591161
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity.
    Florova G; Kazanina G; Reynolds KA
    Biochemistry; 2002 Aug; 41(33):10462-71. PubMed ID: 12173933
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure and malonyl CoA-ACP transacylase binding of streptomyces coelicolor fatty acid synthase acyl carrier protein.
    Arthur CJ; Williams C; Pottage K; Płoskoń E; Findlow SC; Burston SG; Simpson TJ; Crump MP; Crosby J
    ACS Chem Biol; 2009 Aug; 4(8):625-36. PubMed ID: 19555075
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II.
    Kremer L; Nampoothiri KM; Lesjean S; Dover LG; Graham S; Betts J; Brennan PJ; Minnikin DE; Locht C; Besra GS
    J Biol Chem; 2001 Jul; 276(30):27967-74. PubMed ID: 11373295
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Self-malonylation is an intrinsic property of a chemically synthesized type II polyketide synthase acyl carrier protein.
    Arthur CJ; Szafranska A; Evans SE; Findlow SC; Burston SG; Owen P; Clark-Lewis I; Simpson TJ; Crosby J; Crump MP
    Biochemistry; 2005 Nov; 44(46):15414-21. PubMed ID: 16285746
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polyketide synthase acyl carrier protein (ACP) as a substrate and a catalyst for malonyl ACP biosynthesis.
    Zhou P; Florova G; Reynolds KA
    Chem Biol; 1999 Aug; 6(8):577-84. PubMed ID: 10421763
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Catalytic self-acylation of type II polyketide synthase acyl carrier proteins.
    Hitchman TS; Crosby J; Byrom KJ; Cox RJ; Simpson TJ
    Chem Biol; 1998 Jan; 5(1):35-47. PubMed ID: 9479478
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Malonyl-coenzyme A:acyl carrier protein acyltransferase of Streptomyces glaucescens: a possible link between fatty acid and polyketide biosynthesis.
    Summers RG; Ali A; Shen B; Wessel WA; Hutchinson CR
    Biochemistry; 1995 Jul; 34(29):9389-402. PubMed ID: 7626609
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The malonyl transferase activity of type II polyketide synthase acyl carrier proteins.
    Arthur CJ; Szafranska AE; Long J; Mills J; Cox RJ; Findlow SC; Simpson TJ; Crump MP; Crosby J
    Chem Biol; 2006 Jun; 13(6):587-96. PubMed ID: 16793516
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The initiating steps of a type II fatty acid synthase in Plasmodium falciparum are catalyzed by pfACP, pfMCAT, and pfKASIII.
    Prigge ST; He X; Gerena L; Waters NC; Reynolds KA
    Biochemistry; 2003 Feb; 42(4):1160-9. PubMed ID: 12549938
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanistic analysis of a type II polyketide synthase. Role of conserved residues in the beta-ketoacyl synthase-chain length factor heterodimer.
    Dreier J; Khosla C
    Biochemistry; 2000 Feb; 39(8):2088-95. PubMed ID: 10684659
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The R117A variant of the Escherichia coli transacylase FabD synthesizes novel acyl-(acyl carrier proteins).
    Marcella AM; Barb AW
    Appl Microbiol Biotechnol; 2017 Dec; 101(23-24):8431-8441. PubMed ID: 29075826
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase.
    Kumar P; Koppisch AT; Cane DE; Khosla C
    J Am Chem Soc; 2003 Nov; 125(47):14307-12. PubMed ID: 14624579
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Heterologously expressed acyl carrier protein domain of rat fatty acid synthase functions in Escherichia coli fatty acid synthase and Streptomyces coelicolor polyketide synthase systems.
    Tropf S; Revill WP; Bibb MJ; Hopwood DA; Schweizer M
    Chem Biol; 1998 Mar; 5(3):135-46. PubMed ID: 9545424
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dissecting the component reactions catalyzed by the actinorhodin minimal polyketide synthase.
    Beltran-Alvarez P; Cox RJ; Crosby J; Simpson TJ
    Biochemistry; 2007 Dec; 46(50):14672-81. PubMed ID: 18034463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical characterization of the Pseudomonas putida 3-hydroxyacyl ACP:CoA transacylase, which diverts intermediates of fatty acid de novo biosynthesis.
    Hoffmann N; Amara AA; Beermann BB; Qi Q; Hinz HJ; Rehm BH
    J Biol Chem; 2002 Nov; 277(45):42926-36. PubMed ID: 12200450
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overproduction of a functional fatty acid biosynthetic enzyme blocks fatty acid synthesis in Escherichia coli.
    Subrahmanyam S; Cronan JE
    J Bacteriol; 1998 Sep; 180(17):4596-602. PubMed ID: 9721301
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.