These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 11814838)

  • 1. Synthesis and enzymatic evaluation of pyridinium-substituted uracil derivatives as novel inhibitors of thymidine phosphorylase.
    Murray PE; McNally VA; Lockyer SD; Williams KJ; Stratford IJ; Jaffar M; Freeman S
    Bioorg Med Chem; 2002 Mar; 10(3):525-30. PubMed ID: 11814838
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase.
    Nencka R; Votruba I; Hrebabecký H; Tloust'ová E; Horská K; Masojídková M; Holý A
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1335-7. PubMed ID: 16337119
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and enzymatic evaluation of 6-bridged imidazolyluracil derivatives as inhibitors of human thymidine phosphorylase.
    McNally VA; Rajabi M; Gbaj A; Stratford IJ; Edwards PN; Douglas KT; Bryce RA; Jaffar M; Freeman S
    J Pharm Pharmacol; 2007 Apr; 59(4):537-47. PubMed ID: 17430637
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and in vitro evaluation of 5-fluoro-6-[(2-iminopyrrolidin-1-YL)methyl]uracil, TPI(F): an inhibitor of human thymidine phosphorylase (TP).
    Grierson JR; Brockenbrough JS; Rasey JS; Wiens L; Vesselle H
    Nucleosides Nucleotides Nucleic Acids; 2010 Jan; 29(1):49-54. PubMed ID: 20391192
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 1: discovery of novel orally active inhibitors of human thymidine phosphorylase.
    Yano S; Kazuno H; Suzuki N; Emura T; Wierzba K; Yamashita J; Tada Y; Yamada Y; Fukushima M; Asao T
    Bioorg Med Chem; 2004 Jul; 12(13):3431-41. PubMed ID: 15186829
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Microwave-assisted synthesis and biological evaluation of novel uracil derivatives inhibiting human thymidine phosphorylase.
    Corelli F; Botta M; Lossani A; Pasquini S; Spadari S; Focher F
    Farmaco; 2004 Dec; 59(12):987-92. PubMed ID: 15598434
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel nonsubstrate inhibitors of human thymidine phosphorylase, a potential target for tumor-dependent angiogenesis.
    Focher F; Ubiali D; Pregnolato M; Zhi C; Gambino J; Wright GE; Spadari S
    J Med Chem; 2000 Jun; 43(13):2601-7. PubMed ID: 10891120
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of novel 1-(aryl-aldehyde-oxime)uracil derivatives as a new class of thymidine phosphorylase inhibitors.
    Zhao S; Li K; Jin Y; Lin J
    Eur J Med Chem; 2018 Jan; 144():41-51. PubMed ID: 29247859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 2: optimization of inhibitors of human thymidine phosphorylase and their selectivity with uridine phosphorylase.
    Yano S; Kazuno H; Sato T; Suzuki N; Emura T; Wierzba K; Yamashita J; Tada Y; Yamada Y; Fukushima M; Asao T
    Bioorg Med Chem; 2004 Jul; 12(13):3443-50. PubMed ID: 15186830
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of 6-aminouracils and pyrrolo[2,3-d]pyrimidine-2,4-diones and their inhibitory effect on thymidine phosphorylase.
    Hirota K; Sawada M; Sajiki H; Sako M
    Nucleic Acids Symp Ser; 1997; (37):59-60. PubMed ID: 9585998
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase.
    Cole C; Reigan P; Gbaj A; Edwards PN; Douglas KT; Stratford IJ; Freeman S; Jaffar M
    J Med Chem; 2003 Jan; 46(2):207-9. PubMed ID: 12519058
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and enzymatic evaluation of multisubstrate analogue inhibitors of Escherichia coli thymidine phosphorylase.
    Esteban-Gamboa A; Balzarini J; Esnouf R; De Clercq E; Camarasa MJ; Pérez-Pérez MJ
    J Med Chem; 2000 Mar; 43(5):971-83. PubMed ID: 10715161
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
    Reigan P; Edwards PN; Gbaj A; Cole C; Barry ST; Page KM; Ashton SE; Luke RW; Douglas KT; Stratford IJ; Jaffar M; Bryce RA; Freeman S
    J Med Chem; 2005 Jan; 48(2):392-402. PubMed ID: 15658853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thymidine phosphorylase inhibitors with a homophthalimide skeleton.
    Kita T; Takahashi H; Hashimoto Y
    Biol Pharm Bull; 2001 Jul; 24(7):860-2. PubMed ID: 11456133
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 6-substituted 5-fluorouracil derivatives as transition state analogue inhibitors of thymidine phosphorylase.
    Kalman TI; Lai L
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):367-73. PubMed ID: 16247953
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel 6-substituted uracil analogs as inhibitors of the angiogenic actions of thymidine phosphorylase.
    Klein RS; Lenzi M; Lim TH; Hotchkiss KA; Wilson P; Schwartz EL
    Biochem Pharmacol; 2001 Nov; 62(9):1257-63. PubMed ID: 11705459
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure and activity of specific inhibitors of thymidine phosphorylase to potentiate the function of antitumor 2'-deoxyribonucleosides.
    Fukushima M; Suzuki N; Emura T; Yano S; Kazuno H; Tada Y; Yamada Y; Asao T
    Biochem Pharmacol; 2000 May; 59(10):1227-36. PubMed ID: 10736423
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of 5-substituted-6-chlorouracils as efficient inhibitors of human thymidine phosphorylase.
    Nencka R; Votruba I; Hrebabecký H; Jansa P; Tloust'ová E; Horská K; Masojídková M; Holý A
    J Med Chem; 2007 Nov; 50(24):6016-23. PubMed ID: 17963370
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, thymidine phosphorylase, angiogenic inhibition and molecular docking study of isoquinoline derivatives.
    Zaman K; Rahim F; Taha M; Wadood A; Adnan Ali Shah S; Gollapalli M; Ullah F; Ahmed A
    Bioorg Chem; 2019 Aug; 89():102999. PubMed ID: 31151055
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, modelling studies and biological evaluation of 1,3,4-oxadiazole derivatives as potent anticancer agents targeting thymidine phosphorylase enzyme.
    Bajaj S; Kumar MS; Tinwala H; Yc M
    Bioorg Chem; 2021 Jun; 111():104873. PubMed ID: 33845381
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.