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2. Novel direct and indirect cyclin-dependent kinase modulators for the prevention and treatment of human neoplasms. Senderowicz AM Cancer Chemother Pharmacol; 2003 Jul; 52 Suppl 1():S61-73. PubMed ID: 12819936 [TBL] [Abstract][Full Text] [Related]
3. Small molecule modulators of cyclin-dependent kinases for cancer therapy. Senderowicz AM Oncogene; 2000 Dec; 19(56):6600-6. PubMed ID: 11426645 [TBL] [Abstract][Full Text] [Related]
4. UCN-01 dose-dependent inhibition of normal hyperproliferative cells in mice. Redkar AA; Meadows GG; Daoud SS Int J Oncol; 2001 Jul; 19(1):193-9. PubMed ID: 11408942 [TBL] [Abstract][Full Text] [Related]
5. Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells. Harvey S; Decker R; Dai Y; Schaefer G; Tang L; Kramer L; Dent P; Grant S Clin Cancer Res; 2001 Feb; 7(2):320-30. PubMed ID: 11234887 [TBL] [Abstract][Full Text] [Related]
6. 7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53. Shao RG; Shimizu T; Pommier Y Exp Cell Res; 1997 Aug; 234(2):388-97. PubMed ID: 9260909 [TBL] [Abstract][Full Text] [Related]
7. Analogs of staurosporine: potential anticancer drugs? Gescher A Gen Pharmacol; 1998 Nov; 31(5):721-8. PubMed ID: 9809468 [TBL] [Abstract][Full Text] [Related]
8. Potent selective inhibition of 7-O-methyl UCN-01 against protein kinase C. Takahashi I; Kobayashi E; Nakano H; Murakata C; Saitoh H; Suzuki K; Tamaoki T J Pharmacol Exp Ther; 1990 Dec; 255(3):1218-21. PubMed ID: 2262903 [TBL] [Abstract][Full Text] [Related]
9. Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1). Patel V; Lahusen T; Leethanakul C; Igishi T; Kremer M; Quintanilla-Martinez L; Ensley JF; Sausville EA; Gutkind JS; Senderowicz AM Clin Cancer Res; 2002 Nov; 8(11):3549-60. PubMed ID: 12429646 [TBL] [Abstract][Full Text] [Related]
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11. Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms. Sausville EA; Arbuck SG; Messmann R; Headlee D; Bauer KS; Lush RM; Murgo A; Figg WD; Lahusen T; Jaken S; Jing X; Roberge M; Fuse E; Kuwabara T; Senderowicz AM J Clin Oncol; 2001 Apr; 19(8):2319-33. PubMed ID: 11304786 [TBL] [Abstract][Full Text] [Related]
12. UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line. Kawakami K; Futami H; Takahara J; Yamaguchi K Biochem Biophys Res Commun; 1996 Feb; 219(3):778-83. PubMed ID: 8645257 [TBL] [Abstract][Full Text] [Related]
14. 7-hydroxystaurosporine (UCN-01) and ionizing radiation combine to inhibit the growth of Bcl-2-overexpressing U937 leukemia cells through a non-apoptotic mechanism. Cartee L; Sankala H; Davis C; Smith R; Maggio S; Lin PS; Dent P; Grant S Int J Oncol; 2002 Aug; 21(2):351-9. PubMed ID: 12118331 [TBL] [Abstract][Full Text] [Related]
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16. UCN-01 suppresses thymidylate synthase gene expression and enhances 5-fluorouracil-induced apoptosis in a sequence-dependent manner. Hsueh CT; Kelsen D; Schwartz GK Clin Cancer Res; 1998 Sep; 4(9):2201-6. PubMed ID: 9748140 [TBL] [Abstract][Full Text] [Related]
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18. Modulation of apoptosis in rat thymocytes by analogs of staurosporine: lack of direct association with inhibition of protein kinase C. Harkin ST; Cohen GM; Gescher A Mol Pharmacol; 1998 Oct; 54(4):663-70. PubMed ID: 9765509 [TBL] [Abstract][Full Text] [Related]
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