266 related articles for article (PubMed ID: 11823456)
1. Identification of novel point mutations in ERK2 that selectively disrupt binding to MEK1.
Robinson FL; Whitehurst AW; Raman M; Cobb MH
J Biol Chem; 2002 Apr; 277(17):14844-52. PubMed ID: 11823456
[TBL] [Abstract][Full Text] [Related]
2. Loss of active MEK1-ERK1/2 restores epithelial phenotype and morphogenesis in transdifferentiated MDCK cells.
Schramek H; Feifel E; Marschitz I; Golochtchapova N; Gstraunthaler G; Montesano R
Am J Physiol Cell Physiol; 2003 Sep; 285(3):C652-61. PubMed ID: 12900389
[TBL] [Abstract][Full Text] [Related]
3. The MEK1 proline-rich insert is required for efficient activation of the mitogen-activated protein kinases ERK1 and ERK2 in mammalian cells.
Dang A; Frost JA; Cobb MH
J Biol Chem; 1998 Jul; 273(31):19909-13. PubMed ID: 9677429
[TBL] [Abstract][Full Text] [Related]
4. Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes.
Eblen ST; Slack JK; Weber MJ; Catling AD
Mol Cell Biol; 2002 Sep; 22(17):6023-33. PubMed ID: 12167697
[TBL] [Abstract][Full Text] [Related]
5. Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity.
Bardwell AJ; Abdollahi M; Bardwell L
Biochem J; 2003 Mar; 370(Pt 3):1077-85. PubMed ID: 12529172
[TBL] [Abstract][Full Text] [Related]
6. Properties of MEKs, the kinases that phosphorylate and activate the extracellular signal-regulated kinases.
Zheng CF; Guan KL
J Biol Chem; 1993 Nov; 268(32):23933-9. PubMed ID: 8226933
[TBL] [Abstract][Full Text] [Related]
7. A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation.
Robinson MJ; Stippec SA; Goldsmith E; White MA; Cobb MH
Curr Biol; 1998 Oct; 8(21):1141-50. PubMed ID: 9799732
[TBL] [Abstract][Full Text] [Related]
8. MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase.
Xu S; Robbins D; Frost J; Dang A; Lange-Carter C; Cobb MH
Proc Natl Acad Sci U S A; 1995 Jul; 92(15):6808-12. PubMed ID: 7624324
[TBL] [Abstract][Full Text] [Related]
9. Constitutively active mutant of the mitogen-activated protein kinase kinase MEK1 induces epithelial dedifferentiation and growth inhibition in madin-darby canine kidney-C7 cells.
Schramek H; Feifel E; Healy E; Pollack V
J Biol Chem; 1997 Apr; 272(17):11426-33. PubMed ID: 9111053
[TBL] [Abstract][Full Text] [Related]
10. Differential regulation of mitogen-activated protein/ERK kinase (MEK)1 and MEK2 and activation by a Ras-independent mechanism.
Xu S; Khoo S; Dang A; Witt S; Do V; Zhen E; Schaefer EM; Cobb MH
Mol Endocrinol; 1997 Oct; 11(11):1618-25. PubMed ID: 9328344
[TBL] [Abstract][Full Text] [Related]
11. The N-terminal ERK-binding site of MEK1 is required for efficient feedback phosphorylation by ERK2 in vitro and ERK activation in vivo.
Xu Be; Wilsbacher JL; Collisson T; Cobb MH
J Biol Chem; 1999 Nov; 274(48):34029-35. PubMed ID: 10567369
[TBL] [Abstract][Full Text] [Related]
12. Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking.
Xu Be ; Stippec S; Robinson FL; Cobb MH
J Biol Chem; 2001 Jul; 276(28):26509-15. PubMed ID: 11352917
[TBL] [Abstract][Full Text] [Related]
13. Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells.
Wu X; Noh SJ; Zhou G; Dixon JE; Guan KL
J Biol Chem; 1996 Feb; 271(6):3265-71. PubMed ID: 8621729
[TBL] [Abstract][Full Text] [Related]
14. Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia.
Abraham E; Arcaroli J; Shenkar R
J Immunol; 2001 Jan; 166(1):522-30. PubMed ID: 11123332
[TBL] [Abstract][Full Text] [Related]
15. The death effector domain protein PEA-15 prevents nuclear entry of ERK2 by inhibiting required interactions.
Whitehurst AW; Robinson FL; Moore MS; Cobb MH
J Biol Chem; 2004 Mar; 279(13):12840-7. PubMed ID: 14707138
[TBL] [Abstract][Full Text] [Related]
16. A bipartite mechanism for ERK2 recognition by its cognate regulators and substrates.
Zhang J; Zhou B; Zheng CF; Zhang ZY
J Biol Chem; 2003 Aug; 278(32):29901-12. PubMed ID: 12754209
[TBL] [Abstract][Full Text] [Related]
17. Biochemical and biological functions of the N-terminal, noncatalytic domain of extracellular signal-regulated kinase 2.
Eblen ST; Catling AD; Assanah MC; Weber MJ
Mol Cell Biol; 2001 Jan; 21(1):249-59. PubMed ID: 11113199
[TBL] [Abstract][Full Text] [Related]
18. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.
Zheng CF; Guan KL
J Biol Chem; 1993 May; 268(15):11435-9. PubMed ID: 8388392
[TBL] [Abstract][Full Text] [Related]
19. ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1.
Tárrega C; Ríos P; Cejudo-Marín R; Blanco-Aparicio C; van den Berk L; Schepens J; Hendriks W; Tabernero L; Pulido R
J Biol Chem; 2005 Nov; 280(45):37885-94. PubMed ID: 16148006
[TBL] [Abstract][Full Text] [Related]
20. MEK1 is required for PDGF-induced ERK activation and DNA synthesis in tracheal myocytes.
Karpova AY; Abe MK; Li J; Liu PT; Rhee JM; Kuo WL; Hershenson MB
Am J Physiol; 1997 Mar; 272(3 Pt 1):L558-65. PubMed ID: 9124614
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]