BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

274 related articles for article (PubMed ID: 11830531)

  • 1. Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts.
    Geoerger B; Grill J; Opolon P; Morizet J; Aubert G; Terrier-Lacombe MJ; Bressac De-Paillerets B; Barrois M; Feunteun J; Kirn DH; Vassal G
    Cancer Res; 2002 Feb; 62(3):764-72. PubMed ID: 11830531
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oncolytic activity of p53-expressing conditionally replicative adenovirus AdDelta24-p53 against human malignant glioma.
    Geoerger B; Vassal G; Opolon P; Dirven CM; Morizet J; Laudani L; Grill J; Giaccone G; Vandertop WP; Gerritsen WR; van Beusechem VW
    Cancer Res; 2004 Aug; 64(16):5753-9. PubMed ID: 15313916
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A hepatocellular carcinoma-specific adenovirus variant, CV890, eliminates distant human liver tumors in combination with doxorubicin.
    Li Y; Yu DC; Chen Y; Amin P; Zhang H; Nguyen N; Henderson DR
    Cancer Res; 2001 Sep; 61(17):6428-36. PubMed ID: 11522637
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial.
    Nemunaitis J; Ganly I; Khuri F; Arseneau J; Kuhn J; McCarty T; Landers S; Maples P; Romel L; Randlev B; Reid T; Kaye S; Kirn D
    Cancer Res; 2000 Nov; 60(22):6359-66. PubMed ID: 11103798
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of p53, or targeting towards EGFR, enhances the oncolytic potency of conditionally replicative adenovirus against neuroblastoma.
    Geoerger B; van Beusechem VW; Opolon P; Morizet J; Laudani L; Lecluse Y; Barrois M; Idema S; Grill J; Gerritsen WR; Vassal G
    J Gene Med; 2005 May; 7(5):584-94. PubMed ID: 15651070
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer.
    Ganly I; Kirn D; Eckhardt G; Rodriguez GI; Soutar DS; Otto R; Robertson AG; Park O; Gulley ML; Heise C; Von Hoff DD; Kaye SB
    Clin Cancer Res; 2000 Mar; 6(3):798-806. PubMed ID: 10741699
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efficacy of a replication-selective adenovirus against ovarian carcinomatosis is dependent on tumor burden, viral replication and p53 status.
    Heise C; Ganly I; Kim YT; Sampson-Johannes A; Brown R; Kirn D
    Gene Ther; 2000 Nov; 7(22):1925-9. PubMed ID: 11127580
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p53 selective and nonselective replication of an E1B-deleted adenovirus in hepatocellular carcinoma.
    Vollmer CM; Ribas A; Butterfield LH; Dissette VB; Andrews KJ; Eilber FC; Montejo LD; Chen AY; Hu B; Glaspy JA; McBride WH; Economou JS
    Cancer Res; 1999 Sep; 59(17):4369-74. PubMed ID: 10485485
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional interactions of antiapoptotic proteins and tumor necrosis factor in the context of a replication-competent adenovirus.
    Liu TC; Wang Y; Hallden G; Brooks G; Francis J; Lemoine NR; Kirn D
    Gene Ther; 2005 Sep; 12(17):1333-46. PubMed ID: 15920462
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial.
    Mulvihill S; Warren R; Venook A; Adler A; Randlev B; Heise C; Kirn D
    Gene Ther; 2001 Feb; 8(4):308-15. PubMed ID: 11313805
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of E1B gene-attenuated replicating adenoviruses for cancer gene therapy.
    Kim J; Cho JY; Kim JH; Jung KC; Yun CO
    Cancer Gene Ther; 2002 Sep; 9(9):725-36. PubMed ID: 12189522
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor activity of an oncolytic adenovirus-delivered oncogene small interfering RNA.
    Zhang YA; Nemunaitis J; Samuel SK; Chen P; Shen Y; Tong AW
    Cancer Res; 2006 Oct; 66(19):9736-43. PubMed ID: 17018633
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ONYX-015 works synergistically with chemotherapy in lung cancer cell lines and primary cultures freshly made from lung cancer patients.
    You L; Yang CT; Jablons DM
    Cancer Res; 2000 Feb; 60(4):1009-13. PubMed ID: 10706117
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and DeltaE1B adenovirus replication in human cells.
    Steegenga WT; Riteco N; Bos JL
    Oncogene; 1999 Sep; 18(36):5032-43. PubMed ID: 10490840
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Replication and cytolysis of an E1B-attenuated adenovirus in drug-resistant ovarian tumour cells is associated with reduced apoptosis.
    Ganly I; Kim YT; Hann B; Balmain A; Brown R
    Gene Ther; 2001 Mar; 8(5):369-75. PubMed ID: 11313813
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adenovirus lacking the 19-kDa and 55-kDa E1B genes exerts a marked cytotoxic effect in human malignant cells.
    Duque PM; Alonso C; Sánchez-Prieto R; Lleonart M; Martínez C; de Buitrago GG; Cano A; Quintanilla M; Ramon y Cajal S
    Cancer Gene Ther; 1999; 6(6):554-63. PubMed ID: 10608352
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An oncolytic adenovirus selective for retinoblastoma tumor suppressor protein pathway-defective tumors: dependence on E1A, the E2F-1 promoter, and viral replication for selectivity and efficacy.
    Jakubczak JL; Ryan P; Gorziglia M; Clarke L; Hawkins LK; Hay C; Huang Y; Kaloss M; Marinov A; Phipps S; Pinkstaff A; Shirley P; Skripchenko Y; Stewart D; Forry-Schaudies S; Hallenbeck PL
    Cancer Res; 2003 Apr; 63(7):1490-9. PubMed ID: 12670895
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel E1A-E1B mutant adenovirus induces glioma regression in vivo.
    Gomez-Manzano C; Balague C; Alemany R; Lemoine MG; Mitlianga P; Jiang H; Khan A; Alonso M; Lang FF; Conrad CA; Liu TJ; Bekele BN; Yung WK; Fueyo J
    Oncogene; 2004 Mar; 23(10):1821-8. PubMed ID: 15014451
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy.
    Rogulski KR; Freytag SO; Zhang K; Gilbert JD; Paielli DL; Kim JH; Heise CC; Kirn DH
    Cancer Res; 2000 Mar; 60(5):1193-6. PubMed ID: 10728673
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Highly augmented cytopathic effect of a fiber-mutant E1B-defective adenovirus for gene therapy of gliomas.
    Shinoura N; Yoshida Y; Tsunoda R; Ohashi M; Zhang W; Asai A; Kirino T; Hamada H
    Cancer Res; 1999 Jul; 59(14):3411-6. PubMed ID: 10416603
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.