140 related articles for article (PubMed ID: 11832488)
1. Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation.
Kim BT; Kitagawa H; Tamura Ji J; Kusche-Gullberg M; Lindahl U; Sugahara K
J Biol Chem; 2002 Apr; 277(16):13659-65. PubMed ID: 11832488
[TBL] [Abstract][Full Text] [Related]
2. Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis.
Kim BT; Kitagawa H; Tamura J; Saito T; Kusche-Gullberg M; Lindahl U; Sugahara K
Proc Natl Acad Sci U S A; 2001 Jun; 98(13):7176-81. PubMed ID: 11390981
[TBL] [Abstract][Full Text] [Related]
3. Heparan sulfate polymerization in Drosophila.
Izumikawa T; Egusa N; Taniguchi F; Sugahara K; Kitagawa H
J Biol Chem; 2006 Jan; 281(4):1929-34. PubMed ID: 16303756
[TBL] [Abstract][Full Text] [Related]
4. Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation.
Han C; Belenkaya TY; Khodoun M; Tauchi M; Lin X; Lin X
Development; 2004 Apr; 131(7):1563-75. PubMed ID: 14998928
[TBL] [Abstract][Full Text] [Related]
5. rib-2, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes encodes a novel alpha1,4-N-acetylglucosaminyltransferase involved in the biosynthetic initiation and elongation of heparan sulfate.
Kitagawa H; Egusa N; Tamura JI; Kusche-Gullberg M; Lindahl U; Sugahara K
J Biol Chem; 2001 Feb; 276(7):4834-8. PubMed ID: 11121397
[TBL] [Abstract][Full Text] [Related]
6. Biosynthesis of heparan sulfate in EXT1-deficient cells.
Okada M; Nadanaka S; Shoji N; Tamura J; Kitagawa H
Biochem J; 2010 May; 428(3):463-71. PubMed ID: 20377530
[TBL] [Abstract][Full Text] [Related]
7. The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylgalactosamine and N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The key enzyme for the chain initiation of heparan sulfate.
Kitagawa H; Shimakawa H; Sugahara K
J Biol Chem; 1999 May; 274(20):13933-7. PubMed ID: 10318803
[TBL] [Abstract][Full Text] [Related]
8. Reduced Expression of EXTL2, a Member of the Exostosin (EXT) Family of Glycosyltransferases, in Human Embryonic Kidney 293 Cells Results in Longer Heparan Sulfate Chains.
Katta K; Imran T; Busse-Wicher M; Grønning M; Czajkowski S; Kusche-Gullberg M
J Biol Chem; 2015 May; 290(21):13168-77. PubMed ID: 25829497
[TBL] [Abstract][Full Text] [Related]
9. In vitro heparan sulfate polymerization: crucial roles of core protein moieties of primer substrates in addition to the EXT1-EXT2 interaction.
Kim BT; Kitagawa H; Tanaka J; Tamura J; Sugahara K
J Biol Chem; 2003 Oct; 278(43):41618-23. PubMed ID: 12907685
[TBL] [Abstract][Full Text] [Related]
10. Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation.
Busse M; Feta A; Presto J; Wilén M; Grønning M; Kjellén L; Kusche-Gullberg M
J Biol Chem; 2007 Nov; 282(45):32802-10. PubMed ID: 17761672
[TBL] [Abstract][Full Text] [Related]
11. The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate.
Lind T; Tufaro F; McCormick C; Lindahl U; Lidholt K
J Biol Chem; 1998 Oct; 273(41):26265-8. PubMed ID: 9756849
[TBL] [Abstract][Full Text] [Related]
12. Expression of rib-1, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes, is indispensable for heparan sulfate synthesis and embryonic morphogenesis.
Kitagawa H; Izumikawa T; Mizuguchi S; Dejima K; Nomura KH; Egusa N; Taniguchi F; Tamura J; Gengyo-Ando K; Mitani S; Nomura K; Sugahara K
J Biol Chem; 2007 Mar; 282(11):8533-44. PubMed ID: 17237233
[TBL] [Abstract][Full Text] [Related]
13. Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate.
Uyama T; Kitagawa H; Tamura Ji J; Sugahara K
J Biol Chem; 2002 Mar; 277(11):8841-6. PubMed ID: 11788602
[TBL] [Abstract][Full Text] [Related]
14. Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection.
Suda T; Kamiyama S; Suzuki M; Kikuchi N; Nakayama K; Narimatsu H; Jigami Y; Aoki T; Nishihara S
J Biol Chem; 2004 Jun; 279(25):26469-74. PubMed ID: 15082721
[TBL] [Abstract][Full Text] [Related]
15. Etiological point mutations in the hereditary multiple exostoses gene EXT1: a functional analysis of heparan sulfate polymerase activity.
Cheung PK; McCormick C; Crawford BE; Esko JD; Tufaro F; Duncan G
Am J Hum Genet; 2001 Jul; 69(1):55-66. PubMed ID: 11391482
[TBL] [Abstract][Full Text] [Related]
16. Glucuronyltransferase activity of KfiC from Escherichia coli strain K5 requires association of KfiA: KfiC and KfiA are essential enzymes for production of K5 polysaccharide, N-acetylheparosan.
Sugiura N; Baba Y; Kawaguchi Y; Iwatani T; Suzuki K; Kusakabe T; Yamagishi K; Kimata K; Kakuta Y; Watanabe H
J Biol Chem; 2010 Jan; 285(3):1597-606. PubMed ID: 19915003
[TBL] [Abstract][Full Text] [Related]
17. Hereditary multiple exostoses and heparan sulfate polymerization.
Zak BM; Crawford BE; Esko JD
Biochim Biophys Acta; 2002 Dec; 1573(3):346-55. PubMed ID: 12417417
[TBL] [Abstract][Full Text] [Related]
18. EXT gene family member rib-2 is essential for embryonic development and heparan sulfate biosynthesis in Caenorhabditis elegans.
Morio H; Honda Y; Toyoda H; Nakajima M; Kurosawa H; Shirasawa T
Biochem Biophys Res Commun; 2003 Feb; 301(2):317-23. PubMed ID: 12565862
[TBL] [Abstract][Full Text] [Related]
19. Functional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegans.
Blanchette CR; Thackeray A; Perrat PN; Hekimi S; Bénard CY
PLoS Genet; 2017 Jan; 13(1):e1006525. PubMed ID: 28068429
[TBL] [Abstract][Full Text] [Related]
20. Identification and characterization of three Drosophila melanogaster glucuronyltransferases responsible for the synthesis of the conserved glycosaminoglycan-protein linkage region of proteoglycans. Two novel homologs exhibit broad specificity toward oligosaccharides from proteoglycans, glycoproteins, and glycosphingolipids.
Kim BT; Tsuchida K; Lincecum J; Kitagawa H; Bernfield M; Sugahara K
J Biol Chem; 2003 Mar; 278(11):9116-24. PubMed ID: 12511570
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]