195 related articles for article (PubMed ID: 11832492)
1. Differential mitogenic effects of single chain hepatocyte growth factor (HGF)/scatter factor and HGF/NK1 following cleavage by factor Xa.
Pediaditakis P; Monga SP; Mars WM; Michalopoulos GK
J Biol Chem; 2002 Apr; 277(16):14109-15. PubMed ID: 11832492
[TBL] [Abstract][Full Text] [Related]
2. Structural basis of MET receptor dimerization by the bacterial invasion protein InlB and the HGF/SF splice variant NK1.
Niemann HH
Biochim Biophys Acta; 2013 Oct; 1834(10):2195-204. PubMed ID: 23123275
[TBL] [Abstract][Full Text] [Related]
3. Protein engineered variants of hepatocyte growth factor/scatter factor promote proliferation of primary human hepatocytes and in rodent liver.
Ross J; Gherardi E; Mallorqui-Fernandez N; Bocci M; Sobkowicz A; Rees M; Rowe A; Ellmerich S; Massie I; Soeda J; Selden C; Hodgson H
Gastroenterology; 2012 Apr; 142(4):897-906. PubMed ID: 22178588
[TBL] [Abstract][Full Text] [Related]
4. Hepatocyte growth factor (HGF)/NK1 is a naturally occurring HGF/scatter factor variant with partial agonist/antagonist activity.
Cioce V; Csaky KG; Chan AM; Bottaro DP; Taylor WG; Jensen R; Aaronson SA; Rubin JS
J Biol Chem; 1996 May; 271(22):13110-5. PubMed ID: 8662798
[TBL] [Abstract][Full Text] [Related]
5. Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor.
Lietha D; Chirgadze DY; Mulloy B; Blundell TL; Gherardi E
EMBO J; 2001 Oct; 20(20):5543-55. PubMed ID: 11597998
[TBL] [Abstract][Full Text] [Related]
6. Insights into the structure of hepatocyte growth factor/scatter factor (HGF/SF) and implications for receptor activation.
Chirgadze DY; Hepple J; Byrd RA; Sowdhamini R; Blundell TL; Gherardi E
FEBS Lett; 1998 Jun; 430(1-2):126-9. PubMed ID: 9678607
[TBL] [Abstract][Full Text] [Related]
7. Differential effects of hepatocyte growth factor isoforms on epithelial and endothelial tubulogenesis.
Montesano R; Soriano JV; Malinda KM; Ponce ML; Bafico A; Kleinman HK; Bottaro DP; Aaronson SA
Cell Growth Differ; 1998 May; 9(5):355-65. PubMed ID: 9607557
[TBL] [Abstract][Full Text] [Related]
8. NK1, a natural splice variant of hepatocyte growth factor/scatter factor, is a partial agonist in vivo.
Jakubczak JL; LaRochelle WJ; Merlino G
Mol Cell Biol; 1998 Mar; 18(3):1275-83. PubMed ID: 9488442
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding.
Chirgadze DY; Hepple JP; Zhou H; Byrd RA; Blundell TL; Gherardi E
Nat Struct Biol; 1999 Jan; 6(1):72-9. PubMed ID: 9886295
[TBL] [Abstract][Full Text] [Related]
10. Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2.
Schwall RH; Chang LY; Godowski PJ; Kahn DW; Hillan KJ; Bauer KD; Zioncheck TF
J Cell Biol; 1996 May; 133(3):709-18. PubMed ID: 8636243
[TBL] [Abstract][Full Text] [Related]
11. Domain structure of hepatocyte growth factor/scatter factor (HGF/SF).
Gherardi E; Hartmann G; Hepple J; Chirgadze D; Srinivasan N; Blundell T
Ciba Found Symp; 1997; 212():84-93; discussion 93-104. PubMed ID: 9524765
[TBL] [Abstract][Full Text] [Related]
12. Identification of functional domains in the hepatocyte growth factor and its receptor by molecular engineering.
Bardelli A; Ponzetto C; Comoglio PM
J Biotechnol; 1994 Sep; 37(2):109-22. PubMed ID: 7765452
[TBL] [Abstract][Full Text] [Related]
13. A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.
Hartmann G; Naldini L; Weidner KM; Sachs M; Vigna E; Comoglio PM; Birchmeier W
Proc Natl Acad Sci U S A; 1992 Dec; 89(23):11574-8. PubMed ID: 1280830
[TBL] [Abstract][Full Text] [Related]
14. Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo.
Hartmann G; Prospero T; Brinkmann V; Ozcelik C; Winter G; Hepple J; Batley S; Bladt F; Sachs M; Birchmeier C; Birchmeier W; Gherardi E
Curr Biol; 1998 Jan; 8(3):125-34. PubMed ID: 9443912
[TBL] [Abstract][Full Text] [Related]
15. Heparin binding and oligomerization of hepatocyte growth factor/scatter factor isoforms. Heparan sulfate glycosaminoglycan requirement for Met binding and signaling.
Sakata H; Stahl SJ; Taylor WG; Rosenberg JM; Sakaguchi K; Wingfield PT; Rubin JS
J Biol Chem; 1997 Apr; 272(14):9457-63. PubMed ID: 9083085
[TBL] [Abstract][Full Text] [Related]
16. Structural basis of hepatocyte growth factor/scatter factor and MET signalling.
Gherardi E; Sandin S; Petoukhov MV; Finch J; Youles ME; Ofverstedt LG; Miguel RN; Blundell TL; Vande Woude GF; Skoglund U; Svergun DI
Proc Natl Acad Sci U S A; 2006 Mar; 103(11):4046-51. PubMed ID: 16537482
[TBL] [Abstract][Full Text] [Related]
17. Molecular characteristics of HGF-SF and its role in cell motility and invasion.
Weidner KM; Hartmann G; Naldini L; Comoglio PM; Sachs M; Fonatsch C; Rieder H; Birchmeier W
EXS; 1993; 65():311-28. PubMed ID: 8380739
[TBL] [Abstract][Full Text] [Related]
18. Engineering the NK1 fragment of hepatocyte growth factor/scatter factor as a MET receptor antagonist.
Youles M; Holmes O; Petoukhov MV; Nessen MA; Stivala S; Svergun DI; Gherardi E
J Mol Biol; 2008 Mar; 377(3):616-22. PubMed ID: 18291418
[TBL] [Abstract][Full Text] [Related]
19. Disassociation of met-mediated biological responses in vivo: the natural hepatocyte growth factor/scatter factor splice variant NK2 antagonizes growth but facilitates metastasis.
Otsuka T; Jakubczak J; Vieira W; Bottaro DP; Breckenridge D; Larochelle WJ; Merlino G
Mol Cell Biol; 2000 Mar; 20(6):2055-65. PubMed ID: 10688652
[TBL] [Abstract][Full Text] [Related]
20. Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0 A resolution.
Ultsch M; Lokker NA; Godowski PJ; de Vos AM
Structure; 1998 Nov; 6(11):1383-93. PubMed ID: 9817840
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]