BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 11832948)

  • 1. An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3' mispaired DNA.
    Chou KM; Cheng YC
    Nature; 2002 Feb; 415(6872):655-9. PubMed ID: 11832948
    [TBL] [Abstract][Full Text] [Related]  

  • 2. AP endonuclease 1 has no biologically significant 3(')-->5(')-exonuclease activity.
    Lebedeva NA; Khodyreva SN; Favre A; Lavrik OI
    Biochem Biophys Res Commun; 2003 Jan; 300(1):182-7. PubMed ID: 12480540
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An APE that proofreads.
    Jiricny J
    Nature; 2002 Feb; 415(6872):593-4. PubMed ID: 11832924
    [No Abstract]   [Full Text] [Related]  

  • 4. Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease.
    Nguyen LH; Barsky D; Erzberger JP; Wilson DM
    J Mol Biol; 2000 May; 298(3):447-59. PubMed ID: 10772862
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone.
    Luo M; Kelley MR
    Anticancer Res; 2004; 24(4):2127-34. PubMed ID: 15330152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Determinants in nuclease specificity of Ape1 and Ape2, human homologues of Escherichia coli exonuclease III.
    Hadi MZ; Ginalski K; Nguyen LH; Wilson DM
    J Mol Biol; 2002 Feb; 316(3):853-66. PubMed ID: 11866537
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation.
    Robertson KA; Bullock HA; Xu Y; Tritt R; Zimmerman E; Ulbright TM; Foster RS; Einhorn LH; Kelley MR
    Cancer Res; 2001 Mar; 61(5):2220-5. PubMed ID: 11280790
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Probing conformational changes in Ape1 during the progression of base excision repair.
    Yu E; Gaucher SP; Hadi MZ
    Biochemistry; 2010 May; 49(18):3786-96. PubMed ID: 20377204
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer.
    Kelley MR; Cheng L; Foster R; Tritt R; Jiang J; Broshears J; Koch M
    Clin Cancer Res; 2001 Apr; 7(4):824-30. PubMed ID: 11309329
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The exonuclease activity of human apurinic/apyrimidinic endonuclease (APE1). Biochemical properties and inhibition by the natural dinucleotide Gp4G.
    Chou KM; Cheng YC
    J Biol Chem; 2003 May; 278(20):18289-96. PubMed ID: 12624104
    [TBL] [Abstract][Full Text] [Related]  

  • 11. XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions.
    Vidal AE; Boiteux S; Hickson ID; Radicella JP
    EMBO J; 2001 Nov; 20(22):6530-9. PubMed ID: 11707423
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway.
    Daviet S; Couvé-Privat S; Gros L; Shinozuka K; Ide H; Saparbaev M; Ishchenko AA
    DNA Repair (Amst); 2007 Jan; 6(1):8-18. PubMed ID: 16978929
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Properties of and substrate determinants for the exonuclease activity of human apurinic endonuclease Ape1.
    Wilson DM
    J Mol Biol; 2003 Jul; 330(5):1027-37. PubMed ID: 12860125
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 3'-5' exonuclease activity of human apurinic/apyrimidinic endonuclease 1 towards DNAs containing dNMP and their modified analogs at the 3 end of single strand DNA break.
    Dyrkheeva NS; Khodyreva SN; Sukhanova MV; Safronov IV; Dezhurov SV; Lavrik OI
    Biochemistry (Mosc); 2006 Feb; 71(2):200-10. PubMed ID: 16489926
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase beta and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activity.
    Sukhanova MV; Khodyreva SN; Lebedeva NA; Prasad R; Wilson SH; Lavrik OI
    Nucleic Acids Res; 2005; 33(4):1222-9. PubMed ID: 15731342
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Efficiency of exonucleolytic action of apurinic/apyrimidinic endonuclease 1 towards matched and mismatched dNMP at the 3' terminus of different oligomeric DNA structures correlates with thermal stability of DNA duplexes.
    Dyrkheeva NS; Lomzov AA; Pyshnyi DV; Khodyreva SN; Lavrik OI
    Biochim Biophys Acta; 2006 Apr; 1764(4):699-706. PubMed ID: 16481227
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human AP endonuclease (APE1) demonstrates endonucleolytic activity against AP sites in single-stranded DNA.
    Marenstein DR; Wilson DM; Teebor GW
    DNA Repair (Amst); 2004 May; 3(5):527-33. PubMed ID: 15084314
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors.
    Zawahir Z; Dayam R; Deng J; Pereira C; Neamati N
    J Med Chem; 2009 Jan; 52(1):20-32. PubMed ID: 19072053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species.
    Izumi T; Hazra TK; Boldogh I; Tomkinson AE; Park MS; Ikeda S; Mitra S
    Carcinogenesis; 2000 Jul; 21(7):1329-34. PubMed ID: 10874010
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of the 3'-->5'-exonuclease activity of human apurinic endonuclease (Ape1) by its 5'-incised Abasic DNA product.
    Wong D; DeMott MS; Demple B
    J Biol Chem; 2003 Sep; 278(38):36242-9. PubMed ID: 12857737
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.