BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

909 related articles for article (PubMed ID: 11839681)

  • 1. Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia.
    Moon E; Lee R; Near R; Weintraub L; Wolda S; Lerner A
    Clin Cancer Res; 2002 Feb; 8(2):589-95. PubMed ID: 11839681
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Type 4 cAMP phosphodiesterase (PDE4) inhibitors augment glucocorticoid-mediated apoptosis in B cell chronic lymphocytic leukemia (B-CLL) in the absence of exogenous adenylyl cyclase stimulation.
    Tiwari S; Dong H; Kim EJ; Weintraub L; Epstein PM; Lerner A
    Biochem Pharmacol; 2005 Feb; 69(3):473-83. PubMed ID: 15652238
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PDE4 and PDE5 regulate cyclic nucleotides relaxing effects in human umbilical arteries.
    Santos-Silva AJ; Cairrão E; Morgado M; Alvarez E; Verde I
    Eur J Pharmacol; 2008 Mar; 582(1-3):102-9. PubMed ID: 18234184
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential effects of specific phosphodiesterase isoenzyme inhibitors on bovine oocyte meiotic maturation.
    Thomas RE; Armstrong DT; Gilchrist RB
    Dev Biol; 2002 Apr; 244(2):215-25. PubMed ID: 11944932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells.
    Dong H; Zitt C; Auriga C; Hatzelmann A; Epstein PM
    Biochem Pharmacol; 2010 Feb; 79(3):321-9. PubMed ID: 19737543
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modulation of cell adhesion molecule expression and function on human lung microvascular endothelial cells by inhibition of phosphodiesterases 3 and 4.
    Blease K; Burke-Gaffney A; Hellewell PG
    Br J Pharmacol; 1998 May; 124(1):229-37. PubMed ID: 9630364
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dexamethasone down-regulates cAMP-phosphodiesterase in human osteosarcoma cells.
    Ahlström M; Pekkinen M; Huttunen M; Lamberg-Allardt C
    Biochem Pharmacol; 2005 Jan; 69(2):267-75. PubMed ID: 15627479
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oocyte maturation involves compartmentalization and opposing changes of cAMP levels in follicular somatic and germ cells: studies using selective phosphodiesterase inhibitors.
    Tsafriri A; Chun SY; Zhang R; Hsueh AJ; Conti M
    Dev Biol; 1996 Sep; 178(2):393-402. PubMed ID: 8812137
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential regulation of human antigen-specific Th1 and Th2 lymphocyte responses by isozyme selective cyclic nucleotide phosphodiesterase inhibitors.
    Essayan DM; Kagey-Sobotka A; Lichtenstein LM; Huang SK
    J Pharmacol Exp Ther; 1997 Jul; 282(1):505-12. PubMed ID: 9223593
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Type 4 cyclic adenosine monophosphate phosphodiesterase as a therapeutic target in chronic lymphocytic leukemia.
    Kim DH; Lerner A
    Blood; 1998 Oct; 92(7):2484-94. PubMed ID: 9746789
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclic nucleotide phosphodiesterases (PDEs) in human osteoblastic cells; the effect of PDE inhibition on cAMP accumulation.
    Ahlström M; Pekkinen M; Huttunen M; Lamberg-Allardt C
    Cell Mol Biol Lett; 2005; 10(2):305-19. PubMed ID: 16010295
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of distinct cyclic AMP-specific phosphodiesterase (phosphodiesterase type 4) isozymes in human monocytic cells.
    Verghese MW; McConnell RT; Lenhard JM; Hamacher L; Jin SL
    Mol Pharmacol; 1995 Jun; 47(6):1164-71. PubMed ID: 7603456
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential expression of cyclic nucleotide phosphodiesterase 3 and 4 activities in human T cell clones specific for myelin basic protein.
    Ekholm D; Hemmer B; Gao G; Vergelli M; Martin R; Manganiello V
    J Immunol; 1997 Aug; 159(3):1520-9. PubMed ID: 9233651
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anti-inflammatory and utero-relaxant effects in human myometrium of new generation phosphodiesterase 4 inhibitors.
    Oger S; Méhats C; Barnette MS; Ferré F; Cabrol D; Leroy MJ
    Biol Reprod; 2004 Feb; 70(2):458-64. PubMed ID: 14561639
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B.
    Manning CD; McLaughlin MM; Livi GP; Cieslinski LB; Torphy TJ; Barnette MS
    J Pharmacol Exp Ther; 1996 Feb; 276(2):810-8. PubMed ID: 8632354
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphodiesterase 4 inhibitors augment levels of glucocorticoid receptor in B cell chronic lymphocytic leukemia but not in normal circulating hematopoietic cells.
    Meyers JA; Taverna J; Chaves J; Makkinje A; Lerner A
    Clin Cancer Res; 2007 Aug; 13(16):4920-7. PubMed ID: 17699872
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A role for cyclic nucleotide phosphodiesterase 4 in regulation of the growth of human malignant melanoma cells.
    Narita M; Murata T; Shimizu K; Nakagawa T; Sugiyama T; Inui M; Hiramoto K; Tagawa T
    Oncol Rep; 2007 May; 17(5):1133-9. PubMed ID: 17390056
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PDE4 inhibitors activate a mitochondrial apoptotic pathway in chronic lymphocytic leukemia cells that is regulated by protein phosphatase 2A.
    Moon EY; Lerner A
    Blood; 2003 May; 101(10):4122-30. PubMed ID: 12531792
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclic AMP-mediated regulation of vascular smooth muscle cell cyclic AMP phosphodiesterase activity.
    Rose RJ; Liu H; Palmer D; Maurice DH
    Br J Pharmacol; 1997 Sep; 122(2):233-40. PubMed ID: 9313930
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating PDE3 and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel PDE4A splice variant.
    Erdogan S; Houslay MD
    Biochem J; 1997 Jan; 321 ( Pt 1)(Pt 1):165-75. PubMed ID: 9003416
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 46.