131 related articles for article (PubMed ID: 11844685)
1. A novel series of hybrid compounds derived by combining 2-aminotetralin and piperazine fragments: binding activity at D2 and D3 receptors.
Dutta AK; Fei XS; Reith ME
Bioorg Med Chem Lett; 2002 Feb; 12(4):619-22. PubMed ID: 11844685
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological characterization of novel hybrid 7-[[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol and their heterocyclic bioisosteric analogues for dopamine D2 and D3 receptors.
Dutta AK; Venkataraman SK; Fei XS; Kolhatkar R; Zhang S; Reith ME
Bioorg Med Chem; 2004 Aug; 12(16):4361-73. PubMed ID: 15265488
[TBL] [Abstract][Full Text] [Related]
3. Further structure-activity relationships study of hybrid 7-{[2-(4-phenylpiperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol analogues: identification of a high-affinity D3-preferring agonist with potent in vivo activity with long duration of action.
Biswas S; Zhang S; Fernandez F; Ghosh B; Zhen J; Kuzhikandathil E; Reith ME; Dutta AK
J Med Chem; 2008 Jan; 51(1):101-17. PubMed ID: 18072730
[TBL] [Abstract][Full Text] [Related]
4. 2-aminotetralin-derived substituted benzamides with mixed dopamine D2, D3, and serotonin 5-HT1A receptor binding properties: a novel class of potential atypical antipsychotic agents.
Homan EJ; Copinga S; Elfström L; van der Veen T; Hallema JP; Mohell N; Unelius L; Johansson R; Wikström HV; Grol CJ
Bioorg Med Chem; 1998 Nov; 6(11):2111-26. PubMed ID: 9881101
[TBL] [Abstract][Full Text] [Related]
5. Analogues of Arylamide Phenylpiperazine Ligands To Investigate the Factors Influencing D3 Dopamine Receptor Bitropic Binding and Receptor Subtype Selectivity.
Hayatshahi HS; Xu K; Griffin SA; Taylor M; Mach RH; Liu J; Luedtke RR
ACS Chem Neurosci; 2018 Dec; 9(12):2972-2983. PubMed ID: 30010318
[TBL] [Abstract][Full Text] [Related]
6. Investigation of various N-heterocyclic substituted piperazine versions of 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol: effect on affinity and selectivity for dopamine D3 receptor.
Brown DA; Mishra M; Zhang S; Biswas S; Parrington I; Antonio T; Reith ME; Dutta AK
Bioorg Med Chem; 2009 Jun; 17(11):3923-33. PubMed ID: 19427222
[TBL] [Abstract][Full Text] [Related]
7. Design and synthesis of [(2,3-dichlorophenyl)piperazin-1-yl]alkylfluorenylcarboxamides as novel ligands selective for the dopamine D3 receptor subtype.
Robarge MJ; Husbands SM; Kieltyka A; Brodbeck R; Thurkauf A; Newman AH
J Med Chem; 2001 Sep; 44(19):3175-86. PubMed ID: 11543687
[TBL] [Abstract][Full Text] [Related]
8. Further delineation of hydrophobic binding sites in dopamine D(2)/D(3) receptors for N-4 substituents on the piperazine ring of the hybrid template 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol.
Ghosh B; Antonio T; Gopishetty B; Reith M; Dutta A
Bioorg Med Chem; 2010 Aug; 18(15):5661-74. PubMed ID: 20605099
[TBL] [Abstract][Full Text] [Related]
9. Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor.
Grundt P; Carlson EE; Cao J; Bennett CJ; McElveen E; Taylor M; Luedtke RR; Newman AH
J Med Chem; 2005 Feb; 48(3):839-48. PubMed ID: 15689168
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands.
Li A; Mishra Y; Malik M; Wang Q; Li S; Taylor M; Reichert DE; Luedtke RR; Mach RH
Bioorg Med Chem; 2013 Jun; 21(11):2988-98. PubMed ID: 23618707
[TBL] [Abstract][Full Text] [Related]
11. Molecular basis for the binding of 2-aminotetralins to human dopamine D2A and D3 receptors.
Malmberg A; Nordvall G; Johansson AM; Mohell N; Hacksell U
Mol Pharmacol; 1994 Aug; 46(2):299-312. PubMed ID: 8078492
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and biological evaluation of structurally constrained hybrid analogues containing ropinirole moiety as a novel class of potent and selective dopamine D3 receptor ligands.
Zhou B; Hong KH; Ji M; Cai J
Chem Biol Drug Des; 2018 Sep; 92(3):1597-1609. PubMed ID: 29710404
[TBL] [Abstract][Full Text] [Related]
13. Affinity for dopamine D2, D3, and D4 receptors of 2-aminotetralins. Relevance of D2 agonist binding for determination of receptor subtype selectivity.
van Vliet LA; Tepper PG; Dijkstra D; Damsma G; Wikström H; Pugsley TA; Akunne HC; Heffner TG; Glase SA; Wise LD
J Med Chem; 1996 Oct; 39(21):4233-7. PubMed ID: 8863800
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and structure-activity relationships of naphthamides as dopamine D3 receptor ligands.
Huang Y; Luedtke RR; Freeman RA; Wu L; Mach RH
J Med Chem; 2001 May; 44(11):1815-26. PubMed ID: 11356115
[TBL] [Abstract][Full Text] [Related]
15. Structural analogues of 5-OMe-BPAT: synthesis and interactions with dopamine D2, D3, and serotonin 5-HT1A receptors.
Homan EJ; Kroodsma E; Copinga S; Unelius L; Mohell N; Wikström HV; Grol CJ
Bioorg Med Chem; 1999 Jun; 7(6):1111-21. PubMed ID: 10428381
[TBL] [Abstract][Full Text] [Related]
16. Examining the Effects of Sodium Ions on the Binding of Antagonists to Dopamine D2 and D3 Receptors.
Newton CL; Wood MD; Strange PG
PLoS One; 2016; 11(7):e0158808. PubMed ID: 27379794
[TBL] [Abstract][Full Text] [Related]
17. Lack of discrimination by agonists for D2 and D3 dopamine receptors.
Burris KD; Pacheco MA; Filtz TM; Kung MP; Kung HF; Molinoff PB
Neuropsychopharmacology; 1995 Jul; 12(4):335-45. PubMed ID: 7576010
[TBL] [Abstract][Full Text] [Related]
18. Iodinated 2-aminotetralins and 3-amino-1-benzopyrans: ligands for dopamine D2 and D3 receptors.
Chumpradit S; Kung MP; Vessotskie J; Foulon C; Mu M; Kung HF
J Med Chem; 1994 Nov; 37(24):4245-50. PubMed ID: 7990123
[TBL] [Abstract][Full Text] [Related]
19. 1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5.
Perrone R; Berardi F; Colabufo NA; Leopoldo M; Tortorella V
J Med Chem; 1999 Feb; 42(3):490-6. PubMed ID: 9986719
[TBL] [Abstract][Full Text] [Related]
20. Bioisosteric heterocyclic versions of 7-{[2-(4-phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: identification of highly potent and selective agonists for dopamine D3 receptor with potent in vivo activity.
Biswas S; Hazeldine S; Ghosh B; Parrington I; Kuzhikandathil E; Reith ME; Dutta AK
J Med Chem; 2008 May; 51(10):3005-19. PubMed ID: 18410082
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
