189 related articles for article (PubMed ID: 11846779)
1. Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17-21 for the oligomerization state and bioactivity of hCt.
Kazantzis A; Waldner M; Taylor JW; Kapurniotu A
Eur J Biochem; 2002 Feb; 269(3):780-91. PubMed ID: 11846779
[TBL] [Abstract][Full Text] [Related]
2. Rational design, conformational studies and bioactivity of highly potent conformationally constrained calcitonin analogues.
Kapurniotu A; Kayed R; Taylor JW; Voelter W
Eur J Biochem; 1999 Oct; 265(2):606-18. PubMed ID: 10504392
[TBL] [Abstract][Full Text] [Related]
3. Structural and conformational requirements for human calcitonin activity: design, synthesis, and study of lactam-bridged analogues.
Kapurniotu A; Taylor JW
J Med Chem; 1995 Mar; 38(5):836-47. PubMed ID: 7877149
[TBL] [Abstract][Full Text] [Related]
4. Side-chain lactam-bridge conformational constraints differentiate the activities of salmon and human calcitonins and reveal a new design concept for potent calcitonin analogues.
Taylor JW; Jin QK; Sbacchi M; Wang L; Belfiore P; Garnier M; Kazantzis A; Kapurniotu A; Zaratin PF; Scheideler MA
J Med Chem; 2002 Feb; 45(5):1108-21. PubMed ID: 11855991
[TBL] [Abstract][Full Text] [Related]
5. Divergent structural requirements exist for calcitonin receptor binding specificity and adenylate cyclase activation.
Houssami S; Findlay DM; Brady CL; Martin TJ; Epand RM; Moore EE; Murayama E; Tamura T; Orlowski RC; Sexton PM
Mol Pharmacol; 1995 Apr; 47(4):798-809. PubMed ID: 7723741
[TBL] [Abstract][Full Text] [Related]
6. Contribution of conformationally constrained calcitonin (Ct) analogs to the understanding of the structural and conformational requirements of calcitonin bioactivity and to the design of potent agonists.
Kapurniotu A
Curr Med Chem; 2004 Nov; 11(21):2845-65. PubMed ID: 15544479
[TBL] [Abstract][Full Text] [Related]
7. Mono- and bicyclic analogs of parathyroid hormone-related protein. 2. Conformational analysis of antagonists by CD, NMR, and distance geometry calculations.
Maretto S; Mammi S; Bissacco E; Peggion E; Bisello A; Rosenblatt M; Chorev M; Mierke DF
Biochemistry; 1997 Mar; 36(11):3300-7. PubMed ID: 9116008
[TBL] [Abstract][Full Text] [Related]
8. Structure-function studies of analogues of parathyroid hormone (PTH)-1-34 containing beta-amino acid residues in positions 11-13.
Peggion E; Mammi S; Schievano E; Silvestri L; Schiebler L; Bisello A; Rosenblatt M; Chorev M
Biochemistry; 2002 Jun; 41(25):8162-75. PubMed ID: 12069609
[TBL] [Abstract][Full Text] [Related]
9. Constrained corticotropin-releasing factor (CRF) agonists and antagonists with i-(i+3) Glu-Xaa-DXbb-Lys bridges.
Koerber SC; Gulyas J; Lahrichi SL; Corrigan A; Craig AG; Rivier C; Vale W; Rivier J
J Med Chem; 1998 Dec; 41(25):5002-11. PubMed ID: 9836618
[TBL] [Abstract][Full Text] [Related]
10. Structural determinants of salmon calcitonin bioactivity: the role of the Leu-based amphipathic alpha-helix.
Andreotti G; Méndez BL; Amodeo P; Morelli MA; Nakamuta H; Motta A
J Biol Chem; 2006 Aug; 281(34):24193-203. PubMed ID: 16766525
[TBL] [Abstract][Full Text] [Related]
11. Cyclic parathyroid hormone related protein antagonists: lysine 13 to aspartic acid 17 [i to (i + 4)] side chain to side chain lactamization.
Chorev M; Roubini E; McKee RL; Gibbons SW; Goldman ME; Caulfield MP; Rosenblatt M
Biochemistry; 1991 Jun; 30(24):5968-74. PubMed ID: 1646005
[TBL] [Abstract][Full Text] [Related]
12. NMR characterization of monomeric and oligomeric conformations of human calcitonin and its interaction with EGCG.
Huang R; Vivekanandan S; Brender JR; Abe Y; Naito A; Ramamoorthy A
J Mol Biol; 2012 Feb; 416(1):108-20. PubMed ID: 22200484
[TBL] [Abstract][Full Text] [Related]
13. Identification of key components in the irreversibility of salmon calcitonin binding to calcitonin receptors.
Hilton JM; Dowton M; Houssami S; Sexton PM
J Endocrinol; 2000 Jul; 166(1):213-26. PubMed ID: 10856900
[TBL] [Abstract][Full Text] [Related]
14. Conformationally restricted competitive antagonists of human/rat corticotropin-releasing factor.
Miranda A; Koerber SC; Gulyas J; Lahrichi SL; Craig AG; Corrigan A; Hagler A; Rivier C; Vale W; Rivier J
J Med Chem; 1994 May; 37(10):1450-9. PubMed ID: 8182703
[TBL] [Abstract][Full Text] [Related]
15. The glycine residue in cyclic lactam analogues of galanin(1-16)-NH2 is important for stabilizing an N-terminal helix.
Carpenter KA; Schmidt R; Yue SY; Hodzic L; Pou C; Payza K; Godbout C; Brown W; Roberts E
Biochemistry; 1999 Nov; 38(46):15295-304. PubMed ID: 10563815
[TBL] [Abstract][Full Text] [Related]
16. Insights into interactions between the alpha-helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling.
Pham V; Dong M; Wade JD; Miller LJ; Morton CJ; Ng HL; Parker MW; Sexton PM
J Biol Chem; 2005 Aug; 280(31):28610-22. PubMed ID: 15929987
[TBL] [Abstract][Full Text] [Related]
17. Toward parathyroid hormone minimization: conformational studies of cyclic PTH(1-14) analogues.
Tsomaia N; Pellegrini M; Hyde K; Gardella TJ; Mierke DF
Biochemistry; 2004 Jan; 43(3):690-9. PubMed ID: 14730973
[TBL] [Abstract][Full Text] [Related]
18. Effect of carbohydrate structure on biological activity of artificially N-glycosylated eel calcitonin.
Tagashira M; Tanaka A; Hisatani K; Isogai Y; Hori M; Takamatsu S; Fujibayashi Y; Yamamoto K; Haneda K; Inazu T; Toma K
Glycoconj J; 2001 Jun; 18(6):449-55. PubMed ID: 12084980
[TBL] [Abstract][Full Text] [Related]
19. Turn structures in CGRP C-terminal analogues promote stable arrangements of key residue side chains.
Carpenter KA; Schmidt R; von Mentzer B; Haglund U; Roberts E; Walpole C
Biochemistry; 2001 Jul; 40(28):8317-25. PubMed ID: 11444978
[TBL] [Abstract][Full Text] [Related]
20. Human growth hormone-releasing hormone hGHRH(1-29)-NH2: systematic structure-activity relationship studies.
Cervini LA; Donaldson CJ; Koerber SC; Vale WW; Rivier JE
J Med Chem; 1998 Feb; 41(5):717-27. PubMed ID: 9513600
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]