BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 11849043)

  • 1. Glutathione conjugation and DNA adduct formation of dibenzo[a,l]pyrene and benzo[a]pyrene diol epoxides in V79 cells stably expressing different human glutathione transferases.
    Sundberg K; Dreij K; Seidel A; Jernström B
    Chem Res Toxicol; 2002 Feb; 15(2):170-9. PubMed ID: 11849043
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catalytic activities of human alpha class glutathione transferases toward carcinogenic dibenzo[a,l]pyrene diol epoxides.
    Dreij K; Sundberg K; Johansson AS; Nordling E; Seidel A; Persson B; Mannervik B; Jernström B
    Chem Res Toxicol; 2002 Jun; 15(6):825-31. PubMed ID: 12067250
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glutathione conjugation of bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferases M1-1 and P1-1.
    Sundberg K; Widersten M; Seidel A; Mannervik B; Jernström B
    Chem Res Toxicol; 1997 Nov; 10(11):1221-7. PubMed ID: 9403173
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential removal of DNA adducts derived from anti-diol epoxides of dibenzo[a,l]pyrene and benzo[a]pyrene in human cells.
    Dreij K; Seidel A; Jernström B
    Chem Res Toxicol; 2005 Apr; 18(4):655-64. PubMed ID: 15833025
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of the mRNA sequences for Pi class glutathione transferases in different hamster species and the corresponding enzyme activities with anti-benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide.
    Swedmark S; Jernström B; Jenssen D
    Biochem J; 1996 Sep; 318 ( Pt 2)(Pt 2):533-8. PubMed ID: 8809043
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of microsomes and liposomes on glutathione transferase catalysed conjugation of benzo[a]pyrene diol epoxide with glutathione.
    Ooi SG; Jernström B; Ahokas J
    Chem Biol Interact; 1994 Apr; 91(1):15-27. PubMed ID: 8194122
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
    Kushman ME; Kabler SL; Fleming MH; Ravoori S; Gupta RC; Doehmer J; Morrow CS; Townsend AJ
    Carcinogenesis; 2007 Jan; 28(1):207-14. PubMed ID: 16885195
    [TBL] [Abstract][Full Text] [Related]  

  • 8. H2AX phosphorylation in A549 cells induced by the bulky and stable DNA adducts of benzo[a]pyrene and dibenzo[a,l]pyrene diol epoxides.
    Mattsson A; Jernström B; Cotgreave IA; Bajak E
    Chem Biol Interact; 2009 Jan; 177(1):40-7. PubMed ID: 18848825
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glutathione S-transferase A1-1-catalysed conjugation of bay and fjord region diol epoxides or polycyclic aromatic hydrocarbons with glutathione.
    Jernstrom B; Funk M; Frank H; Mannervik B; Seidel A
    Carcinogenesis; 1996 Jul; 17(7):1491-8. PubMed ID: 8706254
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide.
    Lagerqvist A; Håkansson D; Prochazka G; Lundin C; Dreij K; Segerbäck D; Jernström B; Törnqvist M; Seidel A; Erixon K; Jenssen D
    DNA Repair (Amst); 2008 Aug; 7(8):1202-12. PubMed ID: 18479980
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons.
    Sundberg K; Johansson AS; Stenberg G; Widersten M; Seidel A; Mannervik B; Jernström B
    Carcinogenesis; 1998 Mar; 19(3):433-6. PubMed ID: 9525277
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of stably transfected human glutathione S-transferase P1-1 protects against DNA damage by benzo[a]pyrene diol-epoxide in human T47D cells.
    Fields WR; Morrow CS; Doss AJ; Sundberg K; Jernström B; Townsend AJ
    Mol Pharmacol; 1998 Aug; 54(2):298-304. PubMed ID: 9687571
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for catalytic differences between alpha class human glutathione transferases hGSTA1-1 and hGSTA2-2 for glutathione conjugation of environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide.
    Singh SV; Varma V; Zimniak P; Srivastava SK; Marynowski SW; Desai D; Amin S; Ji X
    Biochemistry; 2004 Aug; 43(30):9708-15. PubMed ID: 15274625
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of arginine 216 in catalytic activity of murine Alpha class glutathione transferases mGSTAl-1 and mGSTA2-2 toward carcinogenic diol epoxides of polycyclic aromatic hydrocarbons.
    Pal A; Gu Y; Herzog C; Srivastava SK; Zimniak P; Ji X; Singh SV
    Carcinogenesis; 2001 Aug; 22(8):1301-5. PubMed ID: 11470762
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BPDE-DNA adduct formation and alterations of mRNA, protein, and DNA methylation of CYP1A1, GSTP1, and GSTM1 induced by benzo[a]pyrene and the intervention of aspirin in mice.
    Liu A; Li X; Zhou L; Yan X; Xia N; Song Z; Cao J; Hao Z; Zhang Z; Liang R; Zhang H
    Environ Sci Pollut Res Int; 2023 Oct; 30(48):106549-106561. PubMed ID: 37730975
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anti-diol epoxide of benzo[a]pyrene induces transient Mdm2 and p53 Ser15 phosphorylation, while anti-diol epoxide of dibenzo[a,l]pyrene induces a nontransient p53 Ser15 phosphorylation.
    Pääjärvi G; Jernström B; Seidel A; Stenius U
    Mol Carcinog; 2008 Apr; 47(4):301-9. PubMed ID: 17932951
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase.
    Hu X; Herzog C; Zimniak P; Singh SV
    Cancer Res; 1999 May; 59(10):2358-62. PubMed ID: 10344744
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of glutathione conjugate efflux in cellular protection against benzo[a]pyrene-7,8-diol-9,10-epoxide-induced DNA damage.
    Srivastava SK; Watkins SC; Schuetz E; Singh SV
    Mol Carcinog; 2002 Mar; 33(3):156-62. PubMed ID: 11870881
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An alpha class mouse glutathione S-transferase with exceptional catalytic efficiency in the conjugation of glutathione with 7beta, 8alpha-dihydroxy-9alpha,10alpha-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Hu X; Srivastava SK; Xia H; Awasthi YC; Singh SV
    J Biol Chem; 1996 Dec; 271(51):32684-8. PubMed ID: 8955099
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Hu X; O'Donnell R; Srivastava SK; Xia H; Zimniak P; Nanduri B; Bleicher RJ; Awasthi S; Awasthi YC; Ji X; Singh SV
    Biochem Biophys Res Commun; 1997 Jun; 235(2):424-8. PubMed ID: 9199210
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.