BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 11849052)

  • 1. Synthesis and characterization of site-specific and stereoisomeric fjord dibenzo[a,l]pyrene diol epoxide-N(6)-adenine adducts: unusual thermal stabilization of modified DNA duplexes.
    Ruan Q; Kolbanovskiy A; Zhuang P; Chen J; Krzeminski J; Amin S; Geacintov NE
    Chem Res Toxicol; 2002 Feb; 15(2):249-61. PubMed ID: 11849052
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Spectral and conformational analysis of deoxyadenosine adducts derived from syn- and anti-Dibenzo[a,l]pyrene diol epoxides: fluorescence studies.
    Jankowiak R; Lin CH; Zamzow D; Roberts KP; Li KM; Small GJ
    Chem Res Toxicol; 1999 Sep; 12(9):768-77. PubMed ID: 10490497
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intercalative conformations of the 14R (+)- and 14S (-)-trans-anti-DB[a,l]P-N⁶-dA adducts: molecular modeling and MD simulations.
    Cai Y; Ding S; Geacintov NE; Broyde S
    Chem Res Toxicol; 2011 Apr; 24(4):522-31. PubMed ID: 21361377
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unrepaired fjord region polycyclic aromatic hydrocarbon-DNA adducts in ras codon 61 mutational hot spots.
    Buterin T; Hess MT; Luneva N; Geacintov NE; Amin S; Kroth H; Seidel A; Naegeli H
    Cancer Res; 2000 Apr; 60(7):1849-56. PubMed ID: 10766171
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic activation of racemic and enantiomeric trans-8, 9-dihydroxy-8,9-dihydrodibenzo[a,l]pyrene (dibenzo[def,p]chrysene) to dibenzo[a,l]pyrene-bis-dihydrodiols by induced rat liver microsomes and a recombinant human P450 1A1 system: the role of the K-region-derived metabolic intermediates in the formation of dibenzo[a,l]pyrene-DNA adducts.
    Nesnow S; Davis C; Padgett W; George M; Lambert G; Meyers F; Allison J; Adams L; King LC
    Chem Res Toxicol; 1998 Dec; 11(12):1596-607. PubMed ID: 9860506
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure elucidation of the adducts formed by fjord-region Dibenzo[a,l]pyrene 11,12-dihydrodiol 13,14-epoxides and deoxyadenosine.
    Li KM; George M; Gross ML; Seidel A; Luch A; Rogan EG; Cavalieri EL
    Chem Res Toxicol; 1999 Sep; 12(9):758-67. PubMed ID: 10490496
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability.
    Wu M; Yan S; Patel DJ; Geacintov NE; Broyde S
    Nucleic Acids Res; 2002 Aug; 30(15):3422-32. PubMed ID: 12140327
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tumorigenicity in newborn mice of fjord region and other sterically hindered diol epoxides of benzo[g]chrysene, dibenzo[a,l]pyrene (dibenzo[def,p]chrysene), 4H-cyclopenta[def]chrysene and fluoranthene.
    Amin S; Desai D; Dai W; Harvey RG; Hecht SS
    Carcinogenesis; 1995 Nov; 16(11):2813-7. PubMed ID: 7586203
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stereochemical, structural, and thermodynamic origins of stability differences between stereoisomeric benzo[a]pyrene diol epoxide deoxyadenosine adducts in a DNA mutational hot spot sequence.
    Yan S; Shapiro R; Geacintov NE; Broyde S
    J Am Chem Soc; 2001 Jul; 123(29):7054-66. PubMed ID: 11459484
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclohexene ring and Fjord region twist inversion in stereoisomeric DNA adducts of enantiomeric benzo[c]phenanthrene diol epoxides.
    Wu M; Yan S; Patel DJ; Geacintov NE; Broyde S
    Chem Res Toxicol; 2001 Dec; 14(12):1629-42. PubMed ID: 11743746
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nuclear magnetic resonance studies of an N2-guanine adduct derived from the tumorigen dibenzo[a,l]pyrene in DNA: impact of adduct stereochemistry, size, and local DNA sequence on solution conformations.
    Rodríguez FA; Liu Z; Lin CH; Ding S; Cai Y; Kolbanovskiy A; Kolbanovskiy M; Amin S; Broyde S; Geacintov NE
    Biochemistry; 2014 Mar; 53(11):1827-41. PubMed ID: 24617538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thermodynamic and structural factors in the removal of bulky DNA adducts by the nucleotide excision repair machinery.
    Geacintov NE; Broyde S; Buterin T; Naegeli H; Wu M; Yan S; Patel DJ
    Biopolymers; 2002 Nov; 65(3):202-10. PubMed ID: 12228925
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stereoselective activation of dibenzo[a,l]pyrene and its trans-11,12-dihydrodiol to fjord region 11,12-diol 13,14-epoxides in a human mammary carcinoma MCF-7 cell-mediated V79 cell mutation assay.
    Ralston SL; Coffing SL; Seidel A; Luch A; Platt KL; Baird WM
    Chem Res Toxicol; 1997 Jun; 10(6):687-93. PubMed ID: 9208176
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparison of the morphological transforming activities of dibenzo[a,l]pyrene and benzo[a]pyrene in C3H10T1/2CL8 cells and characterization of the dibenzo[a,l]pyrene-DNA adducts.
    Nesnow S; Davis C; Nelson G; Ross JA; Allison J; Adams L; King LC
    Carcinogenesis; 1997 Oct; 18(10):1973-8. PubMed ID: 9364008
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA damage, repair, and mutation induction by (+)-Syn and (-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxides in mouse cells.
    Yoon JH; Besaratinia A; Feng Z; Tang MS; Amin S; Luch A; Pfeifer GP
    Cancer Res; 2004 Oct; 64(20):7321-8. PubMed ID: 15492252
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Preparation, isolation, and characterization of Dibenzo[a,l]pyrene diol epoxide-deoxyribonucleoside monophosphate adducts by HPLC and fluorescence line-narrowing spectroscopy.
    Devanesan P; Ariese F; Jankowiak R; Small GJ; Rogan EG; Cavalieri EL
    Chem Res Toxicol; 1999 Sep; 12(9):789-95. PubMed ID: 10490499
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mammary carcinogenicity in female CD rats of fjord region diol epoxides of benzo[c]phenanthrene, benzo[g]chrysene and dibenzo[a,l]pyrene.
    Amin S; Krzeminski J; Rivenson A; Kurtzke C; Hecht SS; el-Bayoumy K
    Carcinogenesis; 1995 Aug; 16(8):1971-4. PubMed ID: 7634428
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Site-specific adducts derived from the binding of anti-5-methylchrysene diol epoxide enantiomers to DNA: synthesis and characteristics.
    Xu R; Dwarakanath S; Cosman M; Amin S; Geacintov NE
    Carcinogenesis; 1996 Sep; 17(9):2035-42. PubMed ID: 8824532
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure elucidation of the adducts formed by fjord region Dibenzo[a,l]pyrene-11,12-dihydrodiol 13,14-epoxides with deoxyguanosine.
    Li KM; George M; Gross ML; Lin CH; Jankowiak R; Small GJ; Seidel A; Kroth H; Rogan EG; Cavalieri EL
    Chem Res Toxicol; 1999 Sep; 12(9):778-88. PubMed ID: 10490498
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.
    Mao B; Gu Z; Gorin A; Chen J; Hingerty BE; Amin S; Broyde S; Geacintov NE; Patel DJ
    Biochemistry; 1999 Aug; 38(33):10831-42. PubMed ID: 10451380
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.