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4. Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma. Amin HM; Medeiros LJ; Ma Y; Feretzaki M; Das P; Leventaki V; Rassidakis GZ; O'Connor SL; McDonnell TJ; Lai R Oncogene; 2003 Aug; 22(35):5399-407. PubMed ID: 12934099 [TBL] [Abstract][Full Text] [Related]
5. Signal transducer and activator of transcription-3 activation contributes to high tissue inhibitor of metalloproteinase-1 expression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Lai R; Rassidakis GZ; Medeiros LJ; Ramdas L; Goy AH; Cutler C; Fujio Y; Kunisada K; Amin HM; Gilles F Am J Pathol; 2004 Jun; 164(6):2251-8. PubMed ID: 15161657 [TBL] [Abstract][Full Text] [Related]
6. Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma. Amin HM; McDonnell TJ; Ma Y; Lin Q; Fujio Y; Kunisada K; Leventaki V; Das P; Rassidakis GZ; Cutler C; Medeiros LJ; Lai R Oncogene; 2004 Jul; 23(32):5426-34. PubMed ID: 15184887 [TBL] [Abstract][Full Text] [Related]
7. Constitutive activation of Jak2 contributes to proliferation and resistance to apoptosis in NPM/ALK-transformed cells. Ruchatz H; Coluccia AM; Stano P; Marchesi E; Gambacorti-Passerini C Exp Hematol; 2003 Apr; 31(4):309-15. PubMed ID: 12691918 [TBL] [Abstract][Full Text] [Related]
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9. Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma. Han Y; Amin HM; Frantz C; Franko B; Lee J; Lin Q; Lai R Leukemia; 2006 Sep; 20(9):1602-9. PubMed ID: 16871283 [TBL] [Abstract][Full Text] [Related]
10. STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma. Wu C; Molavi O; Zhang H; Gupta N; Alshareef A; Bone KM; Gopal K; Wu F; Lewis JT; Douglas DN; Kneteman NM; Lai R Blood; 2015 Jul; 126(3):336-45. PubMed ID: 25921060 [TBL] [Abstract][Full Text] [Related]
11. Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity. Cussac D; Greenland C; Roche S; Bai RY; Duyster J; Morris SW; Delsol G; Allouche M; Payrastre B Blood; 2004 Feb; 103(4):1464-71. PubMed ID: 14563642 [TBL] [Abstract][Full Text] [Related]
12. Jak3 activation is significantly associated with ALK expression in anaplastic large cell lymphoma. Lai R; Rassidakis GZ; Lin Q; Atwell C; Medeiros LJ; Amin HM Hum Pathol; 2005 Sep; 36(9):939-44. PubMed ID: 16153455 [TBL] [Abstract][Full Text] [Related]
14. Activation of Rac1 and the exchange factor Vav3 are involved in NPM-ALK signaling in anaplastic large cell lymphomas. Colomba A; Courilleau D; Ramel D; Billadeau DD; Espinos E; Delsol G; Payrastre B; Gaits-Iacovoni F Oncogene; 2008 Apr; 27(19):2728-36. PubMed ID: 17998938 [TBL] [Abstract][Full Text] [Related]
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17. Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes. Piva R; Pellegrino E; Mattioli M; Agnelli L; Lombardi L; Boccalatte F; Costa G; Ruggeri BA; Cheng M; Chiarle R; Palestro G; Neri A; Inghirami G J Clin Invest; 2006 Dec; 116(12):3171-82. PubMed ID: 17111047 [TBL] [Abstract][Full Text] [Related]
18. Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis. Slupianek A; Nieborowska-Skorska M; Hoser G; Morrione A; Majewski M; Xue L; Morris SW; Wasik MA; Skorski T Cancer Res; 2001 Mar; 61(5):2194-9. PubMed ID: 11280786 [TBL] [Abstract][Full Text] [Related]
19. Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target. Chiarle R; Simmons WJ; Cai H; Dhall G; Zamo A; Raz R; Karras JG; Levy DE; Inghirami G Nat Med; 2005 Jun; 11(6):623-9. PubMed ID: 15895073 [TBL] [Abstract][Full Text] [Related]
20. Role of signal transducer and activator of transcription 5 in nucleophosmin/ anaplastic lymphoma kinase-mediated malignant transformation of lymphoid cells. Nieborowska-Skorska M; Slupianek A; Xue L; Zhang Q; Raghunath PN; Hoser G; Wasik MA; Morris SW; Skorski T Cancer Res; 2001 Sep; 61(17):6517-23. PubMed ID: 11522649 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]