These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 11851421)

  • 1. Substrate binding determinants of Trypanosoma brucei gamma-glutamylcysteine synthetase.
    Abbott JJ; Ford JL; Phillips MA
    Biochemistry; 2002 Feb; 41(8):2741-50. PubMed ID: 11851421
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Trypanosoma brucei gamma-glutamylcysteine synthetase. Characterization of the kinetic mechanism and the role of Cys-319 in cystamine inactivation.
    Brekken DL; Phillips MA
    J Biol Chem; 1998 Oct; 273(41):26317-22. PubMed ID: 9756861
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of Trypanosoma brucei gamma-glutamylcysteine synthetase, an essential enzyme in the biosynthesis of trypanothione (diglutathionylspermidine).
    Lueder DV; Phillips MA
    J Biol Chem; 1996 Jul; 271(29):17485-90. PubMed ID: 8663359
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure prediction and active site analysis of the metal binding determinants in gamma -glutamylcysteine synthetase.
    Abbott JJ; Pei J; Ford JL; Qi Y; Grishin VN; Pitcher LA; Phillips MA; Grishin NV
    J Biol Chem; 2001 Nov; 276(45):42099-107. PubMed ID: 11527962
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gamma-glutamylcysteine synthetase-glutathione synthetase: domain structure and identification of residues important in substrate and glutathione binding.
    Janowiak BE; Hayward MA; Peterson FC; Volkman BF; Griffith OW
    Biochemistry; 2006 Sep; 45(35):10461-73. PubMed ID: 16939198
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gene knockdown of gamma-glutamylcysteine synthetase by RNAi in the parasitic protozoa Trypanosoma brucei demonstrates that it is an essential enzyme.
    Huynh TT; Huynh VT; Harmon MA; Phillips MA
    J Biol Chem; 2003 Oct; 278(41):39794-800. PubMed ID: 12888552
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glutathione synthesis in Streptococcus agalactiae. One protein accounts for gamma-glutamylcysteine synthetase and glutathione synthetase activities.
    Janowiak BE; Griffith OW
    J Biol Chem; 2005 Mar; 280(12):11829-39. PubMed ID: 15642737
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase.
    Harris TK; Wu G; Massiah MA; Mildvan AS
    Biochemistry; 2000 Feb; 39(7):1655-74. PubMed ID: 10677214
    [TBL] [Abstract][Full Text] [Related]  

  • 9. YbdK is a carboxylate-amine ligase with a gamma-glutamyl:Cysteine ligase activity: crystal structure and enzymatic assays.
    Lehmann C; Doseeva V; Pullalarevu S; Krajewski W; Howard A; Herzberg O
    Proteins; 2004 Aug; 56(2):376-83. PubMed ID: 15211520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Redox-dependent stability of the γ-glutamylcysteine synthetase enzyme of Escherichia coli: a novel means of redox regulation.
    Kumar S; Kasturia N; Sharma A; Datt M; Bachhawat AK
    Biochem J; 2013 Feb; 449(3):783-94. PubMed ID: 23126248
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altering the reaction specificity of eukaryotic ornithine decarboxylase.
    Jackson LK; Brooks HB; Osterman AL; Goldsmith EJ; Phillips MA
    Biochemistry; 2000 Sep; 39(37):11247-57. PubMed ID: 10985770
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lysine-69 plays a key role in catalysis by ornithine decarboxylase through acceleration of the Schiff base formation, decarboxylation, and product release steps.
    Osterman AL; Brooks HB; Jackson L; Abbott JJ; Phillips MA
    Biochemistry; 1999 Sep; 38(36):11814-26. PubMed ID: 10512638
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cloning, biochemical and phylogenetic characterizations of gamma-glutamylcysteine synthetase from Anabaena sp. PCC 7120.
    Ashida H; Sawa Y; Shibata H
    Plant Cell Physiol; 2005 Apr; 46(4):557-62. PubMed ID: 15695431
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and characterization of a tyramine-glutamate ligase (MfnD) involved in methanofuran biosynthesis.
    Wang Y; Xu H; Harich KC; White RH
    Biochemistry; 2014 Oct; 53(39):6220-30. PubMed ID: 25211225
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reaction mechanism of glutathione synthetase from Arabidopsis thaliana: site-directed mutagenesis of active site residues.
    Herrera K; Cahoon RE; Kumaran S; Jez J
    J Biol Chem; 2007 Jun; 282(23):17157-65. PubMed ID: 17452339
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Escherichia coli gamma-glutamylcysteine synthetase. Two active site metal ions affect substrate and inhibitor binding.
    Kelly BS; Antholine WE; Griffith OW
    J Biol Chem; 2002 Jan; 277(1):50-8. PubMed ID: 11675389
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence for a glutathionyl-enzyme intermediate in the amidase activity of the bifunctional glutathionylspermidine synthetase/amidase from Escherichia coli.
    Lin CH; Kwon DS; Bollinger JM; Walsh CT
    Biochemistry; 1997 Dec; 36(48):14930-8. PubMed ID: 9398217
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Glucose phosphorylation. Site-directed mutations which impair the catalytic function of hexokinase.
    Arora KK; Filburn CR; Pedersen PL
    J Biol Chem; 1991 Mar; 266(9):5359-62. PubMed ID: 2005085
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kinetic, stereochemical, and structural effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase.
    Harris TK; Czerwinski RM; Johnson WH; Legler PM; Abeygunawardana C; Massiah MA; Stivers JT; Whitman CP; Mildvan AS
    Biochemistry; 1999 Sep; 38(38):12343-57. PubMed ID: 10493802
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Site-directed mutagenesis of glutathione synthetase from Escherichia coli B: mapping of the gamma-L-glutamyl-L-cysteine-binding site.
    Hara T; Tanaka T; Kato H; Nishioka T; Oda J
    Protein Eng; 1995 Jul; 8(7):711-6. PubMed ID: 8577699
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.