BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 11856756)

  • 21. MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis.
    Maki H; Sekiguchi M
    Nature; 1992 Jan; 355(6357):273-5. PubMed ID: 1309939
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: sanitization of nucleotide pool.
    Mo JY; Maki H; Sekiguchi M
    Proc Natl Acad Sci U S A; 1992 Nov; 89(22):11021-5. PubMed ID: 1332067
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Transient state kinetic studies of the MutT-catalyzed nucleoside triphosphate pyrophosphohydrolase reaction.
    Xia Z; Azurmendi HF; Mildvan AS
    Biochemistry; 2005 Nov; 44(46):15334-44. PubMed ID: 16285737
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Analysis of mutant frequencies and mutation spectra in hMTH1 knockdown TK6 cells exposed to UV radiation.
    Fotouhi A; Hagos WW; Ilic M; Wojcik A; Harms-Ringdahl M; de Gruijl F; Mullenders L; Jansen JG; Haghdoost S
    Mutat Res; 2013; 751-752():8-14. PubMed ID: 24144844
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Sensitivity of Escherichia coli (MutT) and human (MTH1) 8-oxo-dGTPases to in vitro inhibition by the carcinogenic metals, nickel(II), copper(II), cobalt(II) and cadmium(II).
    Porter DW; Yakushiji H; Nakabeppu Y; Sekiguchi M; Fivash MJ; Kasprzak KS
    Carcinogenesis; 1997 Sep; 18(9):1785-91. PubMed ID: 9328176
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base.
    Nakamura T; Meshitsuka S; Kitagawa S; Abe N; Yamada J; Ishino T; Nakano H; Tsuzuki T; Doi T; Kobayashi Y; Fujii S; Sekiguchi M; Yamagata Y
    J Biol Chem; 2010 Jan; 285(1):444-52. PubMed ID: 19864691
    [TBL] [Abstract][Full Text] [Related]  

  • 27. DNA polymerases involved in the incorporation of oxidized nucleotides into DNA: their efficiency and template base preference.
    Katafuchi A; Nohmi T
    Mutat Res; 2010 Nov; 703(1):24-31. PubMed ID: 20542140
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Suppression of mutagenesis by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate (7,8-dihydro-8-oxo-2'-deoxyguanosine 5'-triphosphate) by human MTH1, MTH2, and NUDT5.
    Hori M; Satou K; Harashima H; Kamiya H
    Free Radic Biol Med; 2010 May; 48(9):1197-201. PubMed ID: 20144704
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A novel Nudix hydrolase for oxidized purine nucleoside triphosphates encoded by ORFYLR151c (PCD1 gene) in Saccharomyces cerevisiae.
    Nunoshiba T; Ishida R; Sasaki M; Iwai S; Nakabeppu Y; Yamamoto K
    Nucleic Acids Res; 2004; 32(18):5339-48. PubMed ID: 15475388
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mycobacterium tuberculosis MutT1 (Rv2985) and ADPRase (Rv1700) proteins constitute a two-stage mechanism of 8-oxo-dGTP and 8-oxo-GTP detoxification and adenosine to cytidine mutation avoidance.
    Patil AG; Sang PB; Govindan A; Varshney U
    J Biol Chem; 2013 Apr; 288(16):11252-62. PubMed ID: 23463507
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Interactions of the products, 8-oxo-dGMP, dGMP, and pyrophosphate with the MutT nucleoside triphosphate pyrophosphohydrolase.
    Saraswat V; Massiah MA; Lopez G; Amzel LM; Mildvan AS
    Biochemistry; 2002 Dec; 41(52):15566-77. PubMed ID: 12501185
    [TBL] [Abstract][Full Text] [Related]  

  • 32. AtNUDX1, an 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase, is responsible for eliminating oxidized nucleotides in Arabidopsis.
    Yoshimura K; Ogawa T; Ueda Y; Shigeoka S
    Plant Cell Physiol; 2007 Oct; 48(10):1438-49. PubMed ID: 17804481
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis.
    Sakumi K; Furuichi M; Tsuzuki T; Kakuma T; Kawabata S; Maki H; Sekiguchi M
    J Biol Chem; 1993 Nov; 268(31):23524-30. PubMed ID: 8226881
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein.
    Shimokawa H; Fujii Y; Furuichi M; Sekiguchi M; Nakabeppu Y
    Nucleic Acids Res; 2000 Sep; 28(17):3240-9. PubMed ID: 10954591
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools.
    Ito R; Hayakawa H; Sekiguchi M; Ishibashi T
    Biochemistry; 2005 May; 44(17):6670-4. PubMed ID: 15850400
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 8-Chloro-dGTP, a hypochlorous acid-modified nucleotide, is hydrolyzed by hMTH1, the human MutT homolog.
    Fujikawa K; Yakushiji H; Nakabeppu Y; Suzuki T; Masuda M; Ohshima H; Kasai H
    FEBS Lett; 2002 Feb; 512(1-3):149-51. PubMed ID: 11852070
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Solution structure and NH exchange studies of the MutT pyrophosphohydrolase complexed with Mg(2+) and 8-oxo-dGMP, a tightly bound product.
    Massiah MA; Saraswat V; Azurmendi HF; Mildvan AS
    Biochemistry; 2003 Sep; 42(34):10140-54. PubMed ID: 12939141
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase.
    Nakabeppu Y; Oka S; Sheng Z; Tsuchimoto D; Sakumi K
    Mutat Res; 2010 Nov; 703(1):51-8. PubMed ID: 20542142
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein.
    Fujikawa K; Kamiya H; Yakushiji H; Fujii Y; Nakabeppu Y; Kasai H
    J Biol Chem; 1999 Jun; 274(26):18201-5. PubMed ID: 10373420
    [TBL] [Abstract][Full Text] [Related]  

  • 40. An increase of oxidised nucleotides activates DNA damage checkpoint pathway that regulates post-embryonic development in Caenorhabditis elegans.
    Sanada Y; Zhang-Akiyama QM
    Mutagenesis; 2014 Mar; 29(2):107-14. PubMed ID: 24435662
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.