BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 11856762)

  • 1. The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.
    van Aubel RAMH; Smeets PHE; Peters JGP; Bindels RJM; Russel FGM
    J Am Soc Nephrol; 2002 Mar; 13(3):595-603. PubMed ID: 11856762
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites.
    Van Aubel RA; Smeets PH; van den Heuvel JJ; Russel FG
    Am J Physiol Renal Physiol; 2005 Feb; 288(2):F327-33. PubMed ID: 15454390
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.
    Bai J; Lai L; Yeo HC; Goh BC; Tan TM
    Int J Biochem Cell Biol; 2004 Feb; 36(2):247-57. PubMed ID: 14643890
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter.
    Smeets PH; van Aubel RA; Wouterse AC; van den Heuvel JJ; Russel FG
    J Am Soc Nephrol; 2004 Nov; 15(11):2828-35. PubMed ID: 15504935
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Construction of triple-transfected cells [organic anion-transporting polypeptide (OATP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for analysis of the sinusoidal function of MRP3 and MRP4.
    Hirouchi M; Kusuhara H; Onuki R; Ogilvie BW; Parkinson A; Sugiyama Y
    Drug Metab Dispos; 2009 Oct; 37(10):2103-11. PubMed ID: 19628752
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4.
    El-Sheikh AA; Greupink R; Wortelboer HM; van den Heuvel JJ; Schreurs M; Koenderink JB; Masereeuw R; Russel FG
    Transl Res; 2013 Dec; 162(6):398-409. PubMed ID: 24036158
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transport of a fluorescent cAMP analog in teleost proximal tubules.
    Reichel V; Masereeuw R; van den Heuvel JJ; Miller DS; Fricker G
    Am J Physiol Regul Integr Comp Physiol; 2007 Dec; 293(6):R2382-9. PubMed ID: 17855498
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluation of the role of breast cancer resistance protein (BCRP/ABCG2) and multidrug resistance-associated protein 4 (MRP4/ABCC4) in the urinary excretion of sulfate and glucuronide metabolites of edaravone (MCI-186; 3-methyl-1-phenyl-2-pyrazolin-5-one).
    Mizuno N; Takahashi T; Kusuhara H; Schuetz JD; Niwa T; Sugiyama Y
    Drug Metab Dispos; 2007 Nov; 35(11):2045-52. PubMed ID: 17682070
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine.
    Chen ZS; Lee K; Kruh GD
    J Biol Chem; 2001 Sep; 276(36):33747-54. PubMed ID: 11447229
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/ABCC2- and MRP4/ABCC4-mediated methotrexate transport.
    El-Sheikh AA; van den Heuvel JJ; Koenderink JB; Russel FG
    J Pharmacol Exp Ther; 2007 Jan; 320(1):229-35. PubMed ID: 17005917
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells.
    Wielinga PR; van der Heijden I; Reid G; Beijnen JH; Wijnholds J; Borst P
    J Biol Chem; 2003 May; 278(20):17664-71. PubMed ID: 12637526
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Polymorphic variants of MRP4/ABCC4 differentially modulate the transport of methylated arsenic metabolites and physiological organic anions.
    Banerjee M; Marensi V; Conseil G; Le XC; Cole SP; Leslie EM
    Biochem Pharmacol; 2016 Nov; 120():72-82. PubMed ID: 27659809
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transport mechanism and affinity of [99mTc]Tc-mercaptoacetyltriglycine ([99mTc]MAG3) on the apical membrane of renal proximal tubule cells.
    Kobayashi M; Nishi K; Mizutani A; Okudaira H; Nakanishi T; Shikano N; Nishii R; Tamai I; Kawai K
    Nucl Med Biol; 2020; 84-85():33-37. PubMed ID: 31986465
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selectivity in the Efflux of Glucuronides by Human Transporters: MRP4 Is Highly Active toward 4-Methylumbelliferone and 1-Naphthol Glucuronides, while MRP3 Exhibits Stereoselective Propranolol Glucuronide Transport.
    Järvinen E; Troberg J; Kidron H; Finel M
    Mol Pharm; 2017 Oct; 14(10):3299-3311. PubMed ID: 28850245
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MRP4-mediated regulation of intracellular cAMP and cGMP levels in trabecular meshwork cells and homeostasis of intraocular pressure.
    Pattabiraman PP; Pecen PE; Rao PV
    Invest Ophthalmol Vis Sci; 2013 Mar; 54(3):1636-49. PubMed ID: 23385799
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multi-drug resistance protein 4 (MRP4)-mediated regulation of fibroblast cell migration reflects a dichotomous role of intracellular cyclic nucleotides.
    Sinha C; Ren A; Arora K; Moon CS; Yarlagadda S; Zhang W; Cheepala SB; Schuetz JD; Naren AP
    J Biol Chem; 2013 Feb; 288(6):3786-94. PubMed ID: 23264633
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.
    Chen ZS; Lee K; Walther S; Raftogianis RB; Kuwano M; Zeng H; Kruh GD
    Cancer Res; 2002 Jun; 62(11):3144-50. PubMed ID: 12036927
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism of active renal tubular efflux of tenofovir.
    Ray AS; Cihlar T; Robinson KL; Tong L; Vela JE; Fuller MD; Wieman LM; Eisenberg EJ; Rhodes GR
    Antimicrob Agents Chemother; 2006 Oct; 50(10):3297-304. PubMed ID: 17005808
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Up-regulation of Mrp4 expression in kidney of Mrp2-deficient TR- rats.
    Chen C; Slitt AL; Dieter MZ; Tanaka Y; Scheffer GL; Klaassen CD
    Biochem Pharmacol; 2005 Oct; 70(7):1088-95. PubMed ID: 16099435
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices.
    Nozaki Y; Kusuhara H; Kondo T; Iwaki M; Shiroyanagi Y; Nakayama H; Horita S; Nakazawa H; Okano T; Sugiyama Y
    J Pharmacol Exp Ther; 2007 Sep; 322(3):1162-70. PubMed ID: 17578901
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.