BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

753 related articles for article (PubMed ID: 11861422)

  • 1. Sphingosine-1-phosphate, a platelet-derived lysophospholipid mediator, negatively regulates cellular Rac activity and cell migration in vascular smooth muscle cells.
    Ryu Y; Takuwa N; Sugimoto N; Sakurada S; Usui S; Okamoto H; Matsui O; Takuwa Y
    Circ Res; 2002 Feb; 90(3):325-32. PubMed ID: 11861422
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3.
    Okamoto H; Takuwa N; Yokomizo T; Sugimoto N; Sakurada S; Shigematsu H; Takuwa Y
    Mol Cell Biol; 2000 Dec; 20(24):9247-61. PubMed ID: 11094076
    [TBL] [Abstract][Full Text] [Related]  

  • 3. G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.
    Takashima S; Sugimoto N; Takuwa N; Okamoto Y; Yoshioka K; Takamura M; Takata S; Kaneko S; Takuwa Y
    Cardiovasc Res; 2008 Sep; 79(4):689-97. PubMed ID: 18480127
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Extracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cells.
    Tamama K; Kon J; Sato K; Tomura H; Kuwabara A; Kimura T; Kanda T; Ohta H; Ui M; Kobayashi I; Okajima F
    Biochem J; 2001 Jan; 353(Pt 1):139-146. PubMed ID: 11115407
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration.
    Kluk MJ; Hla T
    Circ Res; 2001 Sep; 89(6):496-502. PubMed ID: 11557736
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity.
    Arikawa K; Takuwa N; Yamaguchi H; Sugimoto N; Kitayama J; Nagawa H; Takehara K; Takuwa Y
    J Biol Chem; 2003 Aug; 278(35):32841-51. PubMed ID: 12810709
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility.
    Hobson JP; Rosenfeldt HM; Barak LS; Olivera A; Poulton S; Caron MG; Milstien S; Spiegel S
    Science; 2001 Mar; 291(5509):1800-3. PubMed ID: 11230698
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist.
    Osada M; Yatomi Y; Ohmori T; Ikeda H; Ozaki Y
    Biochem Biophys Res Commun; 2002 Dec; 299(3):483-7. PubMed ID: 12445827
    [TBL] [Abstract][Full Text] [Related]  

  • 9. EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration.
    Rosenfeldt HM; Hobson JP; Maceyka M; Olivera A; Nava VE; Milstien S; Spiegel S
    FASEB J; 2001 Dec; 15(14):2649-59. PubMed ID: 11726541
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3.
    Kimura T; Watanabe T; Sato K; Kon J; Tomura H; Tamama K; Kuwabara A; Kanda T; Kobayashi I; Ohta H; Ui M; Okajima F
    Biochem J; 2000 May; 348 Pt 1(Pt 1):71-6. PubMed ID: 10794715
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The sphingosine-1-phosphate receptor EDG-1 is essential for platelet-derived growth factor-induced cell motility.
    Rosenfeldt HM; Hobson JP; Milstien S; Spiegel S
    Biochem Soc Trans; 2001 Nov; 29(Pt 6):836-9. PubMed ID: 11709084
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis.
    Wang F; Van Brocklyn JR; Hobson JP; Movafagh S; Zukowska-Grojec Z; Milstien S; Spiegel S
    J Biol Chem; 1999 Dec; 274(50):35343-50. PubMed ID: 10585401
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Blood lipid mediator sphingosine 1-phosphate potently stimulates platelet-derived growth factor-A and -B chain expression through S1P1-Gi-Ras-MAPK-dependent induction of Kruppel-like factor 5.
    Usui S; Sugimoto N; Takuwa N; Sakagami S; Takata S; Kaneko S; Takuwa Y
    J Biol Chem; 2004 Mar; 279(13):12300-11. PubMed ID: 14711826
    [TBL] [Abstract][Full Text] [Related]  

  • 14. EphrinA1 inactivates integrin-mediated vascular smooth muscle cell spreading via the Rac/PAK pathway.
    Deroanne C; Vouret-Craviari V; Wang B; Pouysségur J
    J Cell Sci; 2003 Apr; 116(Pt 7):1367-76. PubMed ID: 12615978
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis.
    Lee MJ; Thangada S; Paik JH; Sapkota GP; Ancellin N; Chae SS; Wu M; Morales-Ruiz M; Sessa WC; Alessi DR; Hla T
    Mol Cell; 2001 Sep; 8(3):693-704. PubMed ID: 11583630
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis.
    English D; Kovala AT; Welch Z; Harvey KA; Siddiqui RA; Brindley DN; Garcia JG
    J Hematother Stem Cell Res; 1999 Dec; 8(6):627-34. PubMed ID: 10645770
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Platelet-derived growth factor (PDGF)-induced chemotaxis does not require the G protein-coupled receptor S1P1 in murine embryonic fibroblasts and vascular smooth muscle cells.
    Kluk MJ; Colmont C; Wu MT; Hla T
    FEBS Lett; 2003 Jan; 533(1-3):25-8. PubMed ID: 12505153
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison of sphingosine 1-phosphate-induced intracellular signaling pathways in vascular smooth muscles: differential role in vasoconstriction.
    Coussin F; Scott RH; Wise A; Nixon GF
    Circ Res; 2002 Jul; 91(2):151-7. PubMed ID: 12142348
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sphingosine 1-phosphate transactivates the platelet-derived growth factor beta receptor and epidermal growth factor receptor in vascular smooth muscle cells.
    Tanimoto T; Lungu AO; Berk BC
    Circ Res; 2004 Apr; 94(8):1050-8. PubMed ID: 15044318
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical regulation of breast cancer cell expression of S1P2 (Edg-5) and S1P3 (Edg-3) G protein-coupled receptors for sphingosine 1-phosphate.
    Dolezalova H; Shankar G; Huang MC; Bikle DD; Goetzl EJ
    J Cell Biochem; 2003 Mar; 88(4):732-43. PubMed ID: 12577307
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 38.