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6. Alzheimer's disease-linked mutation of presenilin 2 (N141I-PS2) drastically lowers APPalpha secretion: control by the proteasome. Marambaud P; Alves da Costa C; Ancolio K; Checler F Biochem Biophys Res Commun; 1998 Nov; 252(1):134-8. PubMed ID: 9813158 [TBL] [Abstract][Full Text] [Related]
7. The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue. Tomita T; Maruyama K; Saido TC; Kume H; Shinozaki K; Tokuhiro S; Capell A; Walter J; Grünberg J; Haass C; Iwatsubo T; Obata K Proc Natl Acad Sci U S A; 1997 Mar; 94(5):2025-30. PubMed ID: 9050898 [TBL] [Abstract][Full Text] [Related]
8. Pro-apoptotic effect of presenilin 2 (PS2) overexpression is associated with down-regulation of Bcl-2 in cultured neurons. Araki W; Yuasa K; Takeda S; Takeda K; Shirotani K; Takahashi K; Tabira T J Neurochem; 2001 Dec; 79(6):1161-8. PubMed ID: 11752057 [TBL] [Abstract][Full Text] [Related]
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11. Overexpression of wild-type presenilin 2 or its familial Alzheimer's disease-associated mutant does not induce or increase susceptibility to apoptosis in different cell lines. Gamliel A; Teicher C; Hartmann T; Beyreuther K; Stein R Neuroscience; 2003; 117(1):19-28. PubMed ID: 12605888 [TBL] [Abstract][Full Text] [Related]
12. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease. Kim TW; Pettingell WH; Jung YK; Kovacs DM; Tanzi RE Science; 1997 Jul; 277(5324):373-6. PubMed ID: 9219695 [TBL] [Abstract][Full Text] [Related]
13. Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease. Mathews PM; Cataldo AM; Kao BH; Rudnicki AG; Qin X; Yang JL; Jiang Y; Picciano M; Hulette C; Lippa CF; Bird TD; Nochlin D; Walter J; Haass C; Lévesque L; Fraser PE; Andreadis A; Nixon RA Mol Med; 2000 Oct; 6(10):878-91. PubMed ID: 11126202 [TBL] [Abstract][Full Text] [Related]
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17. Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2. Choi EK; Zaidi NF; Miller JS; Crowley AC; Merriam DE; Lilliehook C; Buxbaum JD; Wasco W J Biol Chem; 2001 Jun; 276(22):19197-204. PubMed ID: 11278424 [TBL] [Abstract][Full Text] [Related]
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