These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

321 related articles for article (PubMed ID: 11861912)

  • 21. Interplay between symmetric arginine dimethylation and ubiquitylation regulates TDP1 proteostasis for the repair of topoisomerase I-DNA adducts.
    Bhattacharjee S; Rehman I; Basu S; Nandy S; Richardson JM; Das BB
    Cell Rep; 2022 Jun; 39(11):110940. PubMed ID: 35705029
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents.
    Zhang XR; Wang HW; Tang WL; Zhang Y; Yang H; Hu DX; Ravji A; Marchand C; Kiselev E; Ofori-Atta K; Agama K; Pommier Y; An LK
    J Med Chem; 2018 Nov; 61(22):9908-9930. PubMed ID: 30336023
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Epigenetic and genetic inactivation of tyrosyl-DNA-phosphodiesterase 1 (TDP1) in human lung cancer cells from the NCI-60 panel.
    Gao R; Das BB; Chatterjee R; Abaan OD; Agama K; Matuo R; Vinson C; Meltzer PS; Pommier Y
    DNA Repair (Amst); 2014 Jan; 13():1-9. PubMed ID: 24355542
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.
    Perego P; Cossa G; Tinelli S; Corna E; Carenini N; Gatti L; De Cesare M; Ciusani E; Zunino F; Luison E; Canevari S; Zaffaroni N; Beretta GL
    Biochem Pharmacol; 2012 Jan; 83(1):27-36. PubMed ID: 21978643
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Insights into substrate binding and catalytic mechanism of human tyrosyl-DNA phosphodiesterase (Tdp1) from vanadate and tungstate-inhibited structures.
    Davies DR; Interthal H; Champoux JJ; Hol WG
    J Mol Biol; 2002 Dec; 324(5):917-32. PubMed ID: 12470949
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
    Davies DR; Interthal H; Champoux JJ; Hol WG
    J Med Chem; 2004 Feb; 47(4):829-37. PubMed ID: 14761185
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Inhibition of human tyrosyl-DNA phosphodiesterase by aminoglycoside antibiotics and ribosome inhibitors.
    Liao Z; Thibaut L; Jobson A; Pommier Y
    Mol Pharmacol; 2006 Jul; 70(1):366-72. PubMed ID: 16618796
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Post-translational regulation of Tyrosyl-DNA phosphodiesterase (TDP1 and TDP2) for the repair of the trapped topoisomerase-DNA covalent complex.
    Bhattacharjee S; Rehman I; Nandy S; Das BB
    DNA Repair (Amst); 2022 Mar; 111():103277. PubMed ID: 35101776
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Tyrosyl-DNA-phosphodiesterase I (TDP1) participates in the removal and repair of stabilized-Top2α cleavage complexes in human cells.
    Borda MA; Palmitelli M; Verón G; González-Cid M; de Campos Nebel M
    Mutat Res; 2015 Nov; 781():37-48. PubMed ID: 26421495
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The role of TDP1 from budding yeast in the repair of DNA damage.
    Liu C; Pouliot JJ; Nash HA
    DNA Repair (Amst); 2004 Jun; 3(6):593-601. PubMed ID: 15135727
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage.
    Vance JR; Wilson TE
    Proc Natl Acad Sci U S A; 2002 Oct; 99(21):13669-74. PubMed ID: 12368472
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Structural basis for DNA 3'-end processing by human tyrosyl-DNA phosphodiesterase 1.
    Flett FJ; Ruksenaite E; Armstrong LA; Bharati S; Carloni R; Morris ER; Mackay CL; Interthal H; Richardson JM
    Nat Commun; 2018 Jan; 9(1):24. PubMed ID: 29295983
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Dysregulated human Tyrosyl-DNA phosphodiesterase I acts as cellular toxin.
    Cuya SM; Comeaux EQ; Wanzeck K; Yoon KJ; van Waardenburg RC
    Oncotarget; 2016 Dec; 7(52):86660-86674. PubMed ID: 27893431
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Tyrosyl-DNA phosphodiesterases: rescuing the genome from the risks of relaxation.
    Kawale AS; Povirk LF
    Nucleic Acids Res; 2018 Jan; 46(2):520-537. PubMed ID: 29216365
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.
    Das BB; Dexheimer TS; Maddali K; Pommier Y
    Proc Natl Acad Sci U S A; 2010 Nov; 107(46):19790-5. PubMed ID: 21041670
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Pre-steady state kinetics of DNA binding and abasic site hydrolysis by tyrosyl-DNA phosphodiesterase 1.
    Kuznetsov NA; Lebedeva NA; Kuznetsova AA; Rechkunova NI; Dyrkheeva NS; Kupryushkin MS; Stetsenko DA; Pyshnyi DV; Fedorova OS; Lavrik OI
    J Biomol Struct Dyn; 2017 Aug; 35(11):2314-2327. PubMed ID: 27687298
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions.
    Plo I; Liao ZY; Barceló JM; Kohlhagen G; Caldecott KW; Weinfeld M; Pommier Y
    DNA Repair (Amst); 2003 Oct; 2(10):1087-100. PubMed ID: 13679147
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells.
    Nakano T; Shoulkamy MI; Tsuda M; Sasanuma H; Hirota K; Takata M; Masunaga SI; Takeda S; Ide H; Bessho T; Tano K
    PLoS One; 2020; 15(6):e0234859. PubMed ID: 32589683
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The DNA binding and 3'-end preferential activity of human tyrosyl-DNA phosphodiesterase.
    Dexheimer TS; Stephen AG; Fivash MJ; Fisher RJ; Pommier Y
    Nucleic Acids Res; 2010 Apr; 38(7):2444-52. PubMed ID: 20097655
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and Biological Activities of 11- and 12-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.
    Yang H; Qin C; Wu M; Wang FT; Wang W; Agama K; Pommier Y; Hu DX; An LK
    ChemMedChem; 2023 May; 18(10):e202200593. PubMed ID: 36932053
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.