BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 11865061)

  • 1. Hypoxia links ATR and p53 through replication arrest.
    Hammond EM; Denko NC; Dorie MJ; Abraham RT; Giaccia AJ
    Mol Cell Biol; 2002 Mar; 22(6):1834-43. PubMed ID: 11865061
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest.
    Hammond EM; Green SL; Giaccia AJ
    Mutat Res; 2003 Nov; 532(1-2):205-13. PubMed ID: 14643437
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting radiation-resistant hypoxic tumour cells through ATR inhibition.
    Pires IM; Olcina MM; Anbalagan S; Pollard JR; Reaper PM; Charlton PA; McKenna WG; Hammond EM
    Br J Cancer; 2012 Jul; 107(2):291-9. PubMed ID: 22713662
    [TBL] [Abstract][Full Text] [Related]  

  • 4. S-phase sensing of DNA-protein crosslinks triggers TopBP1-independent ATR activation and p53-mediated cell death by formaldehyde.
    Wong VC; Cash HL; Morse JL; Lu S; Zhitkovich A
    Cell Cycle; 2012 Jul; 11(13):2526-37. PubMed ID: 22722496
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation.
    Hammond EM; Dorie MJ; Giaccia AJ
    J Biol Chem; 2003 Apr; 278(14):12207-13. PubMed ID: 12519769
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.
    Demidova AR; Aau MY; Zhuang L; Yu Q
    J Biol Chem; 2009 Feb; 284(7):4132-9. PubMed ID: 19060337
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional role of Mdm2 phosphorylation by ATR in attenuation of p53 nuclear export.
    Shinozaki T; Nota A; Taya Y; Okamoto K
    Oncogene; 2003 Dec; 22(55):8870-80. PubMed ID: 14654783
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of ATR leads to increased sensitivity to hypoxia/reoxygenation.
    Hammond EM; Dorie MJ; Giaccia AJ
    Cancer Res; 2004 Sep; 64(18):6556-62. PubMed ID: 15374968
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATR controls cellular adaptation to hypoxia through positive regulation of hypoxia-inducible factor 1 (HIF-1) expression.
    Fallone F; Britton S; Nieto L; Salles B; Muller C
    Oncogene; 2013 Sep; 32(37):4387-96. PubMed ID: 23085754
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage.
    Fabbro M; Savage K; Hobson K; Deans AJ; Powell SN; McArthur GA; Khanna KK
    J Biol Chem; 2004 Jul; 279(30):31251-8. PubMed ID: 15159397
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage.
    Helt CE; Cliby WA; Keng PC; Bambara RA; O'Reilly MA
    J Biol Chem; 2005 Jan; 280(2):1186-92. PubMed ID: 15533933
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin.
    Zimmermann M; Arachchige-Don AS; Donaldson MS; Dallapiazza RF; Cowan CE; Horne MC
    J Biol Chem; 2012 Jun; 287(27):22838-53. PubMed ID: 22589537
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.
    Lee AY; Chiba T; Truong LN; Cheng AN; Do J; Cho MJ; Chen L; Wu X
    J Biol Chem; 2012 Jan; 287(4):2531-43. PubMed ID: 22123827
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cadmium-induced DNA damage triggers G(2)/M arrest via chk1/2 and cdc2 in p53-deficient kidney proximal tubule cells.
    Bork U; Lee WK; Kuchler A; Dittmar T; Thévenod F
    Am J Physiol Renal Physiol; 2010 Feb; 298(2):F255-65. PubMed ID: 19923412
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.
    Caporali S; Falcinelli S; Starace G; Russo MT; Bonmassar E; Jiricny J; D'Atri S
    Mol Pharmacol; 2004 Sep; 66(3):478-91. PubMed ID: 15322239
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites.
    Das KC; Dashnamoorthy R
    Am J Physiol Lung Cell Mol Physiol; 2004 Jan; 286(1):L87-97. PubMed ID: 12959929
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress.
    Myers K; Gagou ME; Zuazua-Villar P; Rodriguez R; Meuth M
    PLoS Genet; 2009 Jan; 5(1):e1000324. PubMed ID: 19119425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint.
    Nghiem P; Park PK; Kim Ys YS; Desai BN; Schreiber SL
    J Biol Chem; 2002 Feb; 277(6):4428-34. PubMed ID: 11711532
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reduction of HIF-1α/PD-L1 by Catalytic Topoisomerase Inhibitor Induces Cell Death Through Caspase Activation in Cancer Cells Under Hypoxia.
    Miyata S; Ishii T; Kitanaka S
    Anticancer Res; 2024 Jan; 44(1):49-59. PubMed ID: 38159998
    [TBL] [Abstract][Full Text] [Related]  

  • 20. mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.
    Cam H; Easton JB; High A; Houghton PJ
    Mol Cell; 2010 Nov; 40(4):509-20. PubMed ID: 21095582
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.