BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 11877419)

  • 1. Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulum.
    Wu S; Hu Y; Wang JL; Chatterjee M; Shi Y; Kaufman RJ
    J Biol Chem; 2002 May; 277(20):18077-83. PubMed ID: 11877419
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.
    Koumenis C; Naczki C; Koritzinsky M; Rastani S; Diehl A; Sonenberg N; Koromilas A; Wouters BG
    Mol Cell Biol; 2002 Nov; 22(21):7405-16. PubMed ID: 12370288
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
    Shi J; Li Z; Xu R; Zhang J; Zhou Q; Gao R; Lu H; Lan Y; Zhao K; He H; Gao F; He W
    J Virol; 2022 Jan; 96(1):e0169521. PubMed ID: 34643429
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway.
    Hamanaka RB; Bennett BS; Cullinan SB; Diehl JA
    Mol Biol Cell; 2005 Dec; 16(12):5493-501. PubMed ID: 16176978
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GCN2 phosphorylation of eIF2alpha activates NF-kappaB in response to UV irradiation.
    Jiang HY; Wek RC
    Biochem J; 2005 Jan; 385(Pt 2):371-80. PubMed ID: 15355306
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of nitric-oxide synthase in the regulation of UVB light-induced phosphorylation of the alpha subunit of eukaryotic initiation factor 2.
    Lu W; László CF; Miao Z; Chen H; Wu S
    J Biol Chem; 2009 Sep; 284(36):24281-8. PubMed ID: 19586904
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The roles of translation initiation regulation in ultraviolet light-induced apoptosis.
    Parker SH; Parker TA; George KS; Wu S
    Mol Cell Biochem; 2006 Dec; 293(1-2):173-81. PubMed ID: 16786187
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oxidative stress mediated Ca(2+) release manifests endoplasmic reticulum stress leading to unfolded protein response in UV-B irradiated human skin cells.
    Farrukh MR; Nissar UA; Afnan Q; Rafiq RA; Sharma L; Amin S; Kaiser P; Sharma PR; Tasduq SA
    J Dermatol Sci; 2014 Jul; 75(1):24-35. PubMed ID: 24794973
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PERK-eIF2α-ATF4 pathway mediated by endoplasmic reticulum stress response is involved in osteodifferentiation of human periodontal ligament cells under cyclic mechanical force.
    Yang SY; Wei FL; Hu LH; Wang CL
    Cell Signal; 2016 Aug; 28(8):880-6. PubMed ID: 27079961
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ultraviolet light activates NFkappaB through translational inhibition of IkappaBalpha synthesis.
    Wu S; Tan M; Hu Y; Wang JL; Scheuner D; Kaufman RJ
    J Biol Chem; 2004 Aug; 279(33):34898-902. PubMed ID: 15184376
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2.
    Lu PD; Jousse C; Marciniak SJ; Zhang Y; Novoa I; Scheuner D; Kaufman RJ; Ron D; Harding HP
    EMBO J; 2004 Jan; 23(1):169-79. PubMed ID: 14713949
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A decrease in cellular energy status stimulates PERK-dependent eIF2alpha phosphorylation and regulates protein synthesis in pancreatic beta-cells.
    Gomez E; Powell ML; Bevington A; Herbert TP
    Biochem J; 2008 Mar; 410(3):485-93. PubMed ID: 18052927
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PKR-like endoplasmic reticulum kinase (PERK) activation following brain ischemia is independent of unfolded nascent proteins.
    Sanderson TH; Deogracias MP; Nangia KK; Wang J; Krause GS; Kumar R
    Neuroscience; 2010 Sep; 169(3):1307-14. PubMed ID: 20538047
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Human Cytomegalovirus Endoplasmic Reticulum-Resident Glycoprotein UL148 Activates the Unfolded Protein Response.
    Siddiquey MNA; Zhang H; Nguyen CC; Domma AJ; Kamil JP
    J Virol; 2018 Oct; 92(20):. PubMed ID: 30045994
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of the eukaryotic initiation factor 2 alpha-subunit kinase PERK by tyrosine phosphorylation.
    Su Q; Wang S; Gao HQ; Kazemi S; Harding HP; Ron D; Koromilas AE
    J Biol Chem; 2008 Jan; 283(1):469-475. PubMed ID: 17998206
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Salicylates trigger protein synthesis inhibition in a protein kinase R-like endoplasmic reticulum kinase-dependent manner.
    Silva AM; Wang D; Komar AA; Castilho BA; Williams BR
    J Biol Chem; 2007 Apr; 282(14):10164-71. PubMed ID: 17284450
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The PERK Arm of the Unfolded Protein Response Negatively Regulates Transmissible Gastroenteritis Virus Replication by Suppressing Protein Translation and Promoting Type I Interferon Production.
    Xue M; Fu F; Ma Y; Zhang X; Li L; Feng L; Liu P
    J Virol; 2018 Aug; 92(15):. PubMed ID: 29769338
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha.
    Novoa I; Zeng H; Harding HP; Ron D
    J Cell Biol; 2001 May; 153(5):1011-22. PubMed ID: 11381086
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PKR and PKR-like endoplasmic reticulum kinase induce the proteasome-dependent degradation of cyclin D1 via a mechanism requiring eukaryotic initiation factor 2alpha phosphorylation.
    Raven JF; Baltzis D; Wang S; Mounir Z; Papadakis AI; Gao HQ; Koromilas AE
    J Biol Chem; 2008 Feb; 283(6):3097-3108. PubMed ID: 18063576
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Promastigote to amastigote differentiation of Leishmania is markedly delayed in the absence of PERK eIF2alpha kinase-dependent eIF2alpha phosphorylation.
    Chow C; Cloutier S; Dumas C; Chou MN; Papadopoulou B
    Cell Microbiol; 2011 Jul; 13(7):1059-77. PubMed ID: 21624030
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.