138 related articles for article (PubMed ID: 11880385)
1. Evidence for distinct cation and calcimimetic compound (NPS 568) recognition domains in the transmembrane regions of the human Ca2+ receptor.
Ray K; Northup J
J Biol Chem; 2002 May; 277(21):18908-13. PubMed ID: 11880385
[TBL] [Abstract][Full Text] [Related]
2. Calindol, a positive allosteric modulator of the human Ca(2+) receptor, activates an extracellular ligand-binding domain-deleted rhodopsin-like seven-transmembrane structure in the absence of Ca(2+).
Ray K; Tisdale J; Dodd RH; Dauban P; Ruat M; Northup JK
J Biol Chem; 2005 Nov; 280(44):37013-20. PubMed ID: 16135510
[TBL] [Abstract][Full Text] [Related]
3. Effects of a calcimimetic compound and naturally activating mutations on the human Ca2+ receptor and on Ca2+ receptor/metabotropic glutamate chimeric receptors.
Hauache OM; Hu J; Ray K; Xie R; Jacobson KA; Spiegel AM
Endocrinology; 2000 Nov; 141(11):4156-63. PubMed ID: 11089548
[TBL] [Abstract][Full Text] [Related]
4. Identification of acidic residues in the extracellular loops of the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+ and a positive allosteric modulator.
Hu J; Reyes-Cruz G; Chen W; Jacobson KA; Spiegel AM
J Biol Chem; 2002 Nov; 277(48):46622-31. PubMed ID: 12297503
[TBL] [Abstract][Full Text] [Related]
5. Functional interactions between the extracellular domain and the seven-transmembrane domain in Ca2+ receptor activation.
Hauache OM; Hu J; Ray K; Spiegel AM
Endocrine; 2000 Aug; 13(1):63-70. PubMed ID: 11051048
[TBL] [Abstract][Full Text] [Related]
6. Calcium sensing receptor activation by a calcimimetic suggests a link between cooperativity and intracellular calcium oscillations.
Miedlich S; Gama L; Breitwieser GE
J Biol Chem; 2002 Dec; 277(51):49691-9. PubMed ID: 12399473
[TBL] [Abstract][Full Text] [Related]
7. Allosteric activation of the Ca2+ receptor expressed in Xenopus laevis oocytes by NPS 467 or NPS 568.
Hammerland LG; Garrett JE; Hung BC; Levinthal C; Nemeth EF
Mol Pharmacol; 1998 Jun; 53(6):1083-8. PubMed ID: 9614212
[TBL] [Abstract][Full Text] [Related]
8. Calcimimetics with potent and selective activity on the parathyroid calcium receptor.
Nemeth EF; Steffey ME; Hammerland LG; Hung BC; Van Wagenen BC; DelMar EG; Balandrin MF
Proc Natl Acad Sci U S A; 1998 Mar; 95(7):4040-5. PubMed ID: 9520489
[TBL] [Abstract][Full Text] [Related]
9. 7TM Domain Structure of Adhesion GPCRs.
de Graaf C; Nijmeijer S; Wolf S; Ernst OP
Handb Exp Pharmacol; 2016; 234():43-66. PubMed ID: 27832483
[TBL] [Abstract][Full Text] [Related]
10. Novel inactivating mutations of the calcium-sensing receptor: the calcimimetic NPS R-568 improves signal transduction of mutant receptors.
Rus R; Haag C; Bumke-Vogt C; Bähr V; Mayr B; Möhlig M; Schulze E; Frank-Raue K; Raue F; Schöfl C
J Clin Endocrinol Metab; 2008 Dec; 93(12):4797-803. PubMed ID: 18796518
[TBL] [Abstract][Full Text] [Related]
11. Positive and negative allosteric modulators promote biased signaling at the calcium-sensing receptor.
Davey AE; Leach K; Valant C; Conigrave AD; Sexton PM; Christopoulos A
Endocrinology; 2012 Mar; 153(3):1232-41. PubMed ID: 22210744
[TBL] [Abstract][Full Text] [Related]
12. A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+.
Hu J; McLarnon SJ; Mora S; Jiang J; Thomas C; Jacobson KA; Spiegel AM
J Biol Chem; 2005 Feb; 280(6):5113-20. PubMed ID: 15591042
[TBL] [Abstract][Full Text] [Related]
13. An acquired hypocalciuric hypercalcemia autoantibody induces allosteric transition among active human Ca-sensing receptor conformations.
Makita N; Sato J; Manaka K; Shoji Y; Oishi A; Hashimoto M; Fujita T; Iiri T
Proc Natl Acad Sci U S A; 2007 Mar; 104(13):5443-8. PubMed ID: 17372216
[TBL] [Abstract][Full Text] [Related]
14. The Venus Fly Trap domain of the extracellular Ca2+ -sensing receptor is required for L-amino acid sensing.
Mun HC; Franks AH; Culverston EL; Krapcho K; Nemeth EF; Conigrave AD
J Biol Chem; 2004 Dec; 279(50):51739-44. PubMed ID: 15579475
[TBL] [Abstract][Full Text] [Related]
15. NPS R-568: a type II calcimimetic compound that acts on parathyroid cell calcium receptor of rats to reduce plasma levels of parathyroid hormone and calcium.
Fox J; Lowe SH; Petty BA; Nemeth EF
J Pharmacol Exp Ther; 1999 Aug; 290(2):473-9. PubMed ID: 10411552
[TBL] [Abstract][Full Text] [Related]
16. Effects of divalent cations and of a calcimimetic on adrenocorticotropic hormone release in pituitary tumor cells.
Ferry S; Chatel B; Dodd RH; Lair C; Gully D; Maffrand JP; Ruat M
Biochem Biophys Res Commun; 1997 Sep; 238(3):866-73. PubMed ID: 9325183
[TBL] [Abstract][Full Text] [Related]
17. Calcyclin mediates serum response element (SRE) activation by an osteoblastic extracellular cation-sensing mechanism.
Tu Q; Pi M; Quarles LD
J Bone Miner Res; 2003 Oct; 18(10):1825-33. PubMed ID: 14584893
[TBL] [Abstract][Full Text] [Related]
18. Domains determining ligand specificity for Ca2+ receptors.
Hammerland LG; Krapcho KJ; Garrett JE; Alasti N; Hung BC; Simin RT; Levinthal C; Nemeth EF; Fuller FH
Mol Pharmacol; 1999 Apr; 55(4):642-8. PubMed ID: 10101021
[TBL] [Abstract][Full Text] [Related]
19. Residue 826 in the calcium-sensing receptor is implicated in the response to calcium and to R-568 calcimimetic compound.
Alvarez-Hernández D; González-Suárez I; Fernández-Martín JL; Rodríguez I; Santamaría I; Coto E; Cannata-Andía JB
Calcif Tissue Int; 2010 Mar; 86(3):227-33. PubMed ID: 20130845
[TBL] [Abstract][Full Text] [Related]
20. A novel cation-sensing mechanism in osteoblasts is a molecular target for strontium.
Pi M; Quarles LD
J Bone Miner Res; 2004 May; 19(5):862-9. PubMed ID: 15068510
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
