BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 11884228)

  • 1. Signaling pathways of D3-phosphoinositide-binding kinases in T cells and their regulation by PTEN.
    Seminario MC; Wange RL
    Semin Immunol; 2002 Feb; 14(1):27-36. PubMed ID: 11884228
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors.
    Freeburn RW; Wright KL; Burgess SJ; Astoul E; Cantrell DA; Ward SG
    J Immunol; 2002 Nov; 169(10):5441-50. PubMed ID: 12421919
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PTEN permits acute increases in D3-phosphoinositide levels following TCR stimulation but inhibits distal signaling events by reducing the basal activity of Akt.
    Seminario MC; Precht P; Bunnell SC; Warren SE; Morris CM; Taub D; Wange RL
    Eur J Immunol; 2004 Nov; 34(11):3165-75. PubMed ID: 15468057
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the PI3K/Akt pathway in Jurkat T cells.
    Xu Z; Stokoe D; Kane LP; Weiss A
    Cell Growth Differ; 2002 Jul; 13(7):285-96. PubMed ID: 12133897
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase.
    Wang X; Gjörloff-Wingren A; Saxena M; Pathan N; Reed JC; Mustelin T
    J Immunol; 2000 Feb; 164(4):1934-9. PubMed ID: 10657643
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation.
    Shan X; Czar MJ; Bunnell SC; Liu P; Liu Y; Schwartzberg PL; Wange RL
    Mol Cell Biol; 2000 Sep; 20(18):6945-57. PubMed ID: 10958690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lipid phosphatases in the regulation of T cell activation: living up to their PTEN-tial.
    Seminario MC; Wange RL
    Immunol Rev; 2003 Apr; 192():80-97. PubMed ID: 12670397
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells.
    Choi Y; Zhang J; Murga C; Yu H; Koller E; Monia BP; Gutkind JS; Li W
    Oncogene; 2002 Aug; 21(34):5289-300. PubMed ID: 12149650
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
    Vazquez F; Sellers WR
    Biochim Biophys Acta; 2000 Feb; 1470(1):M21-35. PubMed ID: 10656987
    [No Abstract]   [Full Text] [Related]  

  • 10. Heterologous regulation of chemokine receptor signaling by the lipid phosphatase SHIP in lymphocytes.
    Wain CM; Westwick J; Ward SG
    Cell Signal; 2005 Oct; 17(10):1194-202. PubMed ID: 16038794
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
    Ono H; Katagiri H; Funaki M; Anai M; Inukai K; Fukushima Y; Sakoda H; Ogihara T; Onishi Y; Fujishiro M; Kikuchi M; Oka Y; Asano T
    Mol Endocrinol; 2001 Aug; 15(8):1411-22. PubMed ID: 11463863
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells.
    Asano T; Yao Y; Zhu J; Li D; Abbruzzese JL; Reddy SA
    Oncogene; 2004 Nov; 23(53):8571-80. PubMed ID: 15467756
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways.
    Gao X; Neufeld TP; Pan D
    Dev Biol; 2000 May; 221(2):404-18. PubMed ID: 10790335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON; Akca H; Mayo LD; Gustin JA; Maehama T; Dixon JE; Donner DB
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4640-5. PubMed ID: 11287630
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.
    Paramio JM; Navarro M; Segrelles C; Gómez-Casero E; Jorcano JL
    Oncogene; 1999 Dec; 18(52):7462-8. PubMed ID: 10602505
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells.
    Yi HK; Kim SY; Hwang PH; Kim CY; Yang DH; Oh Y; Lee DY
    Biochem Biophys Res Commun; 2005 May; 330(3):760-7. PubMed ID: 15809062
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antagonism of PI 3-kinase-dependent signalling pathways by the tumour suppressor protein, PTEN.
    Downes CP; Bennett D; McConnachie G; Leslie NR; Pass I; MacPhee C; Patel L; Gray A
    Biochem Soc Trans; 2001 Nov; 29(Pt 6):846-51. PubMed ID: 11709086
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Open heart surgery of PI-3 kinase signaling.
    Woodgett JR
    Cell Cycle; 2002; 1(6):404-5. PubMed ID: 12548014
    [No Abstract]   [Full Text] [Related]  

  • 19. Abnormal PTEN expression in portal hypertensive gastric mucosa: a key to impaired PI 3-kinase/Akt activation and delayed injury healing?
    Tsugawa K; Jones MK; Akahoshi T; Moon WS; Maehara Y; Hashizume M; Sarfeh IJ; Tarnawski AS
    FASEB J; 2003 Dec; 17(15):2316-8. PubMed ID: 14525948
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways.
    Merlot S; Firtel RA
    J Cell Sci; 2003 Sep; 116(Pt 17):3471-8. PubMed ID: 12893811
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.