BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

263 related articles for article (PubMed ID: 11884607)

  • 1. ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells.
    Muraoka RS; Lenferink AE; Law B; Hamilton E; Brantley DM; Roebuck LR; Arteaga CL
    Mol Cell Biol; 2002 Apr; 22(7):2204-19. PubMed ID: 11884607
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice.
    Lenferink AE; Simpson JF; Shawver LK; Coffey RJ; Forbes JT; Arteaga CL
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9609-14. PubMed ID: 10931950
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclin-dependent kinase inhibitor p27(Kip1) is required for mouse mammary gland morphogenesis and function.
    Muraoka RS; Lenferink AE; Simpson J; Brantley DM; Roebuck LR; Yakes FM; Arteaga CL
    J Cell Biol; 2001 May; 153(5):917-32. PubMed ID: 11381079
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
    Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway.
    Lee RJ; Albanese C; Fu M; D'Amico M; Lin B; Watanabe G; Haines GK; Siegel PM; Hung MC; Yarden Y; Horowitz JM; Muller WJ; Pestell RG
    Mol Cell Biol; 2000 Jan; 20(2):672-83. PubMed ID: 10611246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cell transformation by the E5/E8 protein of bovine papillomavirus type 4. p27(Kip1), Elevated through increased protein synthesis is sequestered by cyclin D1-CDK4 complexes.
    O'Brien V; Grindlay GJ; Campo MS
    J Biol Chem; 2001 Sep; 276(36):33861-8. PubMed ID: 11448948
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sustained trophism of the mammary gland is sufficient to accelerate and synchronize development of ErbB2/Neu-induced tumors.
    Landis MD; Seachrist DD; Abdul-Karim FW; Keri RA
    Oncogene; 2006 Jun; 25(23):3325-34. PubMed ID: 16434967
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms of energy restriction: effects of corticosterone on cell growth, cell cycle machinery, and apoptosis.
    Jiang W; Zhu Z; Bhatia N; Agarwal R; Thompson HJ
    Cancer Res; 2002 Sep; 62(18):5280-7. PubMed ID: 12234997
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mouse mammary hyperplasias and neoplasias exhibit different patterns of cyclins D1 and D2 binding to cdk4.
    Said TK; Luo L; Medina D
    Carcinogenesis; 1995 Oct; 16(10):2507-13. PubMed ID: 7586159
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling.
    Brantley-Sieders DM; Zhuang G; Hicks D; Fang WB; Hwang Y; Cates JM; Coffman K; Jackson D; Bruckheimer E; Muraoka-Cook RS; Chen J
    J Clin Invest; 2008 Jan; 118(1):64-78. PubMed ID: 18079969
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclin-dependent kinase (cdk) inhibitors/cdk4/cdk2 complexes in early stages of mouse mammary preneoplasia.
    Said TK; Moraes RC; Singh U; Kittrell FS; Medina D
    Cell Growth Differ; 2001 Jun; 12(6):285-95. PubMed ID: 11432803
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells.
    Ryo A; Liou YC; Wulf G; Nakamura M; Lee SW; Lu KP
    Mol Cell Biol; 2002 Aug; 22(15):5281-95. PubMed ID: 12101225
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.
    Cabodi S; Tinnirello A; Di Stefano P; BisarĂ² B; Ambrosino E; Castellano I; Sapino A; Arisio R; Cavallo F; Forni G; Glukhova M; Silengo L; Altruda F; Turco E; Tarone G; Defilippi P
    Cancer Res; 2006 May; 66(9):4672-80. PubMed ID: 16651418
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The cyclin-dependent kinase inhibitor p27 (Kip1) regulates both DNA synthesis and apoptosis in mammary epithelium but is not required for its functional development during pregnancy.
    Davison EA; Lee CS; Naylor MJ; Oakes SR; Sutherland RL; Hennighausen L; Ormandy CJ; Musgrove EA
    Mol Endocrinol; 2003 Dec; 17(12):2436-47. PubMed ID: 12933906
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of the CDK inhibitor p27 (Kip1) in mammary development and carcinogenesis: insights from knockout mice.
    Musgrove EA; Davison EA; Ormandy CJ
    J Mammary Gland Biol Neoplasia; 2004 Jan; 9(1):55-66. PubMed ID: 15082918
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Progesterone inhibits estrogen-induced cyclin D1 and cdk4 nuclear translocation, cyclin E- and cyclin A-cdk2 kinase activation, and cell proliferation in uterine epithelial cells in mice.
    Tong W; Pollard JW
    Mol Cell Biol; 1999 Mar; 19(3):2251-64. PubMed ID: 10022912
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Down-regulation of p27Kip1 promotes cell proliferation of rat neonatal cardiomyocytes induced by nuclear expression of cyclin D1 and CDK4. Evidence for impaired Skp2-dependent degradation of p27 in terminal differentiation.
    Tamamori-Adachi M; Hayashida K; Nobori K; Omizu C; Yamada K; Sakamoto N; Kamura T; Fukuda K; Ogawa S; Nakayama KI; Kitajima S
    J Biol Chem; 2004 Nov; 279(48):50429-36. PubMed ID: 15371458
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional analysis of cyclin D2 and p27(Kip1) in cyclin D2 transgenic mouse mammary gland during development.
    Kong G; Chua SS; Yijun Y; Kittrell F; Moraes RC; Medina D; Said TK
    Oncogene; 2002 Oct; 21(47):7214-25. PubMed ID: 12370811
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice.
    Geng Y; Yu Q; Sicinska E; Das M; Bronson RT; Sicinski P
    Proc Natl Acad Sci U S A; 2001 Jan; 98(1):194-9. PubMed ID: 11134518
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New functional activities for the p21 family of CDK inhibitors.
    LaBaer J; Garrett MD; Stevenson LF; Slingerland JM; Sandhu C; Chou HS; Fattaey A; Harlow E
    Genes Dev; 1997 Apr; 11(7):847-62. PubMed ID: 9106657
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.