BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 11889117)

  • 1. Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export.
    Ishida N; Hara T; Kamura T; Yoshida M; Nakayama K; Nakayama KI
    J Biol Chem; 2002 Apr; 277(17):14355-8. PubMed ID: 11889117
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis.
    Connor MK; Kotchetkov R; Cariou S; Resch A; Lupetti R; Beniston RG; Melchior F; Hengst L; Slingerland JM
    Mol Biol Cell; 2003 Jan; 14(1):201-13. PubMed ID: 12529437
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase.
    Kamura T; Hara T; Matsumoto M; Ishida N; Okumura F; Hatakeyama S; Yoshida M; Nakayama K; Nakayama KI
    Nat Cell Biol; 2004 Dec; 6(12):1229-35. PubMed ID: 15531880
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability.
    Ishida N; Kitagawa M; Hatakeyama S; Nakayama K
    J Biol Chem; 2000 Aug; 275(33):25146-54. PubMed ID: 10831586
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex.
    Tomoda K; Kubota Y; Arata Y; Mori S; Maeda M; Tanaka T; Yoshida M; Yoneda-Kato N; Kato JY
    J Biol Chem; 2002 Jan; 277(3):2302-10. PubMed ID: 11704659
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway.
    Foster JS; Fernando RI; Ishida N; Nakayama KI; Wimalasena J
    J Biol Chem; 2003 Oct; 278(42):41355-66. PubMed ID: 12904306
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway.
    Hara T; Kamura T; Nakayama K; Oshikawa K; Hatakeyama S; Nakayama K
    J Biol Chem; 2001 Dec; 276(52):48937-43. PubMed ID: 11682478
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry.
    Shin I; Rotty J; Wu FY; Arteaga CL
    J Biol Chem; 2005 Feb; 280(7):6055-63. PubMed ID: 15579463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.
    Boehm M; Yoshimoto T; Crook MF; Nallamshetty S; True A; Nabel GJ; Nabel EG
    EMBO J; 2002 Jul; 21(13):3390-401. PubMed ID: 12093740
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis.
    Rodier G; Montagnoli A; Di Marcotullio L; Coulombe P; Draetta GF; Pagano M; Meloche S
    EMBO J; 2001 Dec; 20(23):6672-82. PubMed ID: 11726503
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutations of phosphorylation sites Ser10 and Thr187 of p27Kip1 abolish cytoplasmic redistribution but do not abrogate G0/1 phase arrest in the HepG2 cell line.
    Guan X; Chen L; Wang J; Geng H; Chu X; Zhang Q; Du L; De W
    Biochem Biophys Res Commun; 2006 Sep; 347(3):601-7. PubMed ID: 16842750
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation.
    Kotake Y; Nakayama K; Ishida N; Nakayama KI
    J Biol Chem; 2005 Jan; 280(2):1095-102. PubMed ID: 15528185
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.
    Lin R; Wang TT; Miller WH; White JH
    Endocrinology; 2003 Mar; 144(3):749-53. PubMed ID: 12586749
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kip1, a potential role for elevated Skp2 expression.
    Zhang L; Wang C
    J Biol Chem; 2003 Jan; 278(1):27-36. PubMed ID: 12401804
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement of two distinct ubiquitin E3 ligase systems for p27 degradation in corneal endothelial cells.
    Lee JG; Kay EP
    Invest Ophthalmol Vis Sci; 2008 Jan; 49(1):189-96. PubMed ID: 18172092
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1.
    Chopra S; Fernandez De Mattos S; Lam EW; Mann DJ
    J Biol Chem; 2002 Sep; 277(36):32413-6. PubMed ID: 12119282
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p27(Kip1) signaling: Transcriptional and post-translational regulation.
    Hnit SS; Xie C; Yao M; Holst J; Bensoussan A; De Souza P; Li Z; Dong Q
    Int J Biochem Cell Biol; 2015 Nov; 68():9-14. PubMed ID: 26279144
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase.
    Deng X; Mercer SE; Shah S; Ewton DZ; Friedman E
    J Biol Chem; 2004 May; 279(21):22498-504. PubMed ID: 15010468
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization.
    Fujita N; Sato S; Katayama K; Tsuruo T
    J Biol Chem; 2002 Aug; 277(32):28706-13. PubMed ID: 12042314
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.
    Koga H; Harada M; Ohtsubo M; Shishido S; Kumemura H; Hanada S; Taniguchi E; Yamashita K; Kumashiro R; Ueno T; Sata M
    Hepatology; 2003 May; 37(5):1086-96. PubMed ID: 12717389
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.