These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 11891276)

  • 41. The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment.
    Rothnie A; Storm J; McMahon R; Taylor A; Kerr ID; Callaghan R
    FEBS Lett; 2005 Jul; 579(18):3984-90. PubMed ID: 16004994
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Identification of putative binding sites of P-glycoprotein based on its homology model.
    Globisch C; Pajeva IK; Wiese M
    ChemMedChem; 2008 Feb; 3(2):280-95. PubMed ID: 18175303
    [TBL] [Abstract][Full Text] [Related]  

  • 43. The W232R suppressor mutation promotes maturation of a truncation mutant lacking both nucleotide-binding domains and restores interdomain assembly and activity of P-glycoprotein processing mutants.
    Loo TW; Bartlett MC; Clarke DM
    Biochemistry; 2011 Feb; 50(5):672-85. PubMed ID: 21182301
    [TBL] [Abstract][Full Text] [Related]  

  • 44. The "LSGGQ" motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing walker A sequence.
    Loo TW; Bartlett MC; Clarke DM
    J Biol Chem; 2002 Nov; 277(44):41303-6. PubMed ID: 12226074
    [TBL] [Abstract][Full Text] [Related]  

  • 45. P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site.
    Urbatsch IL; Sankaran B; Weber J; Senior AE
    J Biol Chem; 1995 Aug; 270(33):19383-90. PubMed ID: 7642618
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Molecular motions involved in Na-K-Cl cotransporter-mediated ion transport and transporter activation revealed by internal cross-linking between transmembrane domains 10 and 11/12.
    Monette MY; Somasekharan S; Forbush B
    J Biol Chem; 2014 Mar; 289(11):7569-79. PubMed ID: 24451383
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Kinetic validation of the models for P-glycoprotein ATP hydrolysis and vanadate-induced trapping. Proposal for additional steps.
    Lugo MR; Sharom FJ
    PLoS One; 2014; 9(6):e98804. PubMed ID: 24897122
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Predicting the three-dimensional structure of human P-glycoprotein in absence of ATP by computational techniques embodying crosslinking data: insight into the mechanism of ligand migration and binding sites.
    Vandevuer S; Van Bambeke F; Tulkens PM; Prévost M
    Proteins; 2006 May; 63(3):466-78. PubMed ID: 16463278
    [TBL] [Abstract][Full Text] [Related]  

  • 49. The flexibility of P-glycoprotein for its poly-specific drug binding from molecular dynamics simulations.
    Liu M; Hou T; Feng Z; Li Y
    J Biomol Struct Dyn; 2013; 31(6):612-29. PubMed ID: 22888853
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Transmembrane helix 12 modulates progression of the ATP catalytic cycle in ABCB1.
    Crowley E; O'Mara ML; Reynolds C; Tieleman DP; Storm J; Kerr ID; Callaghan R
    Biochemistry; 2009 Jul; 48(26):6249-58. PubMed ID: 19456124
    [TBL] [Abstract][Full Text] [Related]  

  • 51. The topography of transmembrane segment six is altered during the catalytic cycle of P-glycoprotein.
    Rothnie A; Storm J; Campbell J; Linton KJ; Kerr ID; Callaghan R
    J Biol Chem; 2004 Aug; 279(33):34913-21. PubMed ID: 15192095
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Nonequivalent nucleotide trapping in the two nucleotide binding folds of the human multidrug resistance protein MRP1.
    Nagata K; Nishitani M; Matsuo M; Kioka N; Amachi T; Ueda K
    J Biol Chem; 2000 Jun; 275(23):17626-30. PubMed ID: 10747957
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Conserved Walker A cysteines 431 and 1074 in human P-glycoprotein are accessible to thiol-specific agents in the apo and ADP-vanadate trapped conformations.
    Sim HM; Bhatnagar J; Chufan EE; Kapoor K; Ambudkar SV
    Biochemistry; 2013 Oct; 52(41):7327-38. PubMed ID: 24053441
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Evidence for modulatory sites at the lipid-protein interface of the human multidrug transporter P-glycoprotein.
    Mandal D; Moitra K; Ghosh D; Xia D; Dey S
    Biochemistry; 2012 Apr; 51(13):2852-66. PubMed ID: 22360349
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Exploiting reaction intermediates of the ATPase reaction to elucidate the mechanism of transport by P-glycoprotein (ABCB1).
    Sauna ZE; Nandigama K; Ambudkar SV
    J Biol Chem; 2006 Sep; 281(36):26501-11. PubMed ID: 16844693
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Identification of residues in the drug-binding site of human P-glycoprotein using a thiol-reactive substrate.
    Loo TW; Clarke DM
    J Biol Chem; 1997 Dec; 272(51):31945-8. PubMed ID: 9405384
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Identification of two different states of P-glycoprotein in its catalytic cycle: role of the linker region in the transition between these two states.
    Rao US; Nuti SL
    J Biol Chem; 2003 Nov; 278(47):46576-82. PubMed ID: 12968025
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Accessibility of substituted cysteines in TM2 and TM10 transmembrane segments in the
    Nishtala SN; Arora A; Reyes J; Akabas MH
    J Biol Chem; 2019 Feb; 294(6):1924-1935. PubMed ID: 30541922
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane.
    Carey Hulyer AR; Briggs DA; O'Mara ML; Kerr ID; Harmer JR; Callaghan R
    J Struct Biol; 2020 Jul; 211(1):107513. PubMed ID: 32339763
    [TBL] [Abstract][Full Text] [Related]  

  • 60. The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis.
    van Wonderen JH; McMahon RM; O'Mara ML; McDevitt CA; Thomson AJ; Kerr ID; MacMillan F; Callaghan R
    FEBS J; 2014 May; 281(9):2190-2201. PubMed ID: 24597976
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.