139 related articles for article (PubMed ID: 11896054)
1. X-ray structure of a serine protease acyl-enzyme complex at 0.95-A resolution.
Katona G; Wilmouth RC; Wright PA; Berglund GI; Hajdu J; Neutze R; Schofield CJ
J Biol Chem; 2002 Jun; 277(24):21962-70. PubMed ID: 11896054
[TBL] [Abstract][Full Text] [Related]
2. 'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexes.
Wright PA; Wilmouth RC; Clifton IJ; Schofield CJ
Biochem J; 2000 Oct; 351 Pt 2(Pt 2):335-40. PubMed ID: 11023818
[TBL] [Abstract][Full Text] [Related]
3. Kinetic and crystallographic analysis of complexes formed between elastase and peptides from beta-casein.
Wright PA; Wilmouth RC; Clifton IJ; Schofield CJ
Eur J Biochem; 2001 May; 268(10):2969-74. PubMed ID: 11358514
[TBL] [Abstract][Full Text] [Related]
4. Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase.
Wilmouth RC; Clifton IJ; Robinson CV; Roach PL; Aplin RT; Westwood NJ; Hajdu J; Schofield CJ
Nat Struct Biol; 1997 Jun; 4(6):456-62. PubMed ID: 9187653
[TBL] [Abstract][Full Text] [Related]
5. X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate.
Wilmouth RC; Edman K; Neutze R; Wright PA; Clifton IJ; Schneider TR; Schofield CJ; Hajdu J
Nat Struct Biol; 2001 Aug; 8(8):689-94. PubMed ID: 11473259
[TBL] [Abstract][Full Text] [Related]
6. Molecular dynamics simulations of the acyl-enzyme and the tetrahedral intermediate in the deacylation step of serine proteases.
Topf M; Várnai P; Schofield CJ; Richards WG
Proteins; 2002 May; 47(3):357-69. PubMed ID: 11948789
[TBL] [Abstract][Full Text] [Related]
7. Structural analyses on intermediates in serine protease catalysis.
Liu B; Schofield CJ; Wilmouth RC
J Biol Chem; 2006 Aug; 281(33):24024-35. PubMed ID: 16754679
[TBL] [Abstract][Full Text] [Related]
8. Direct crystallographic observation of an acyl-enzyme intermediate in the elastase-catalyzed hydrolysis of a peptidyl ester substrate: Exploiting the "glass transition" in protein dynamics.
Ding X; Rasmussen BF; Petsko GA; Ringe D
Bioorg Chem; 2006 Dec; 34(6):410-23. PubMed ID: 17083959
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex.
Wilmouth RC; Westwood NJ; Anderson K; Brownlee W; Claridge TD; Clifton IJ; Pritchard GJ; Aplin RT; Schofield CJ
Biochemistry; 1998 Dec; 37(50):17506-13. PubMed ID: 9860865
[TBL] [Abstract][Full Text] [Related]
10. Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.
Tsunemi M; Matsuura Y; Sakakibara S; Katsube Y
Biochemistry; 1996 Sep; 35(36):11570-6. PubMed ID: 8794736
[TBL] [Abstract][Full Text] [Related]
11. Enzyme:substrate hydrogen bond shortening during the acylation phase of serine protease catalysis.
Fodor K; Harmat V; Neutze R; Szilágyi L; Gráf L; Katona G
Biochemistry; 2006 Feb; 45(7):2114-21. PubMed ID: 16475800
[TBL] [Abstract][Full Text] [Related]
12. Three-dimensional Structure of a Kunitz-type Inhibitor in Complex with an Elastase-like Enzyme.
García-Fernández R; Perbandt M; Rehders D; Ziegelmüller P; Piganeau N; Hahn U; Betzel C; Chávez Mde L; Redecke L
J Biol Chem; 2015 May; 290(22):14154-65. PubMed ID: 25878249
[TBL] [Abstract][Full Text] [Related]
13. Ab initio QM/MM dynamics simulation of the tetrahedral intermediate of serine proteases: insights into the active site hydrogen-bonding network.
Topf M; Várnai P; Richards WG
J Am Chem Soc; 2002 Dec; 124(49):14780-8. PubMed ID: 12465991
[TBL] [Abstract][Full Text] [Related]
14. Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase.
Ding X; Rasmussen BF; Petsko GA; Ringe D
Biochemistry; 1994 Aug; 33(31):9285-93. PubMed ID: 8049229
[TBL] [Abstract][Full Text] [Related]
15. Atomic resolution structure of native porcine pancreatic elastase at 1.1 A.
Würtele M; Hahn M; Hilpert K; Höhne W
Acta Crystallogr D Biol Crystallogr; 2000 Apr; 56(Pt 4):520-3. PubMed ID: 10739939
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.
Lee J; Feldman AR; Delmas B; Paetzel M
J Biol Chem; 2007 Aug; 282(34):24928-37. PubMed ID: 17553791
[TBL] [Abstract][Full Text] [Related]
17. Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.
Wilmouth RC; Kassamally S; Westwood NJ; Sheppard RJ; Claridge TD; Aplin RT; Wright PA; Pritchard GJ; Schofield CJ
Biochemistry; 1999 Jun; 38(25):7989-98. PubMed ID: 10387042
[TBL] [Abstract][Full Text] [Related]
18. Additivity-based design of the strongest possible turkey ovomucoid third domain inhibitors for porcine pancreatic elastase (PPE) and Streptomyces griseus protease B (SGPB).
Qasim MA; Wang L; Qasim S; Lu S; Lu W; Wynn R; Yi ZP; Laskowski M
FEBS Lett; 2013 Sep; 587(18):3021-6. PubMed ID: 23892073
[TBL] [Abstract][Full Text] [Related]
19. Combined high-resolution neutron and X-ray analysis of inhibited elastase confirms the active-site oxyanion hole but rules against a low-barrier hydrogen bond.
Tamada T; Kinoshita T; Kurihara K; Adachi M; Ohhara T; Imai K; Kuroki R; Tada T
J Am Chem Soc; 2009 Aug; 131(31):11033-40. PubMed ID: 19603802
[TBL] [Abstract][Full Text] [Related]
20. Heterogeneity in serpin-protease complexes as demonstrated by differences in the mechanism of complex breakdown.
Plotnick MI; Samakur M; Wang ZM; Liu X; Rubin H; Schechter NM; Selwood T
Biochemistry; 2002 Jan; 41(1):334-42. PubMed ID: 11772033
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]