BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

327 related articles for article (PubMed ID: 11900542)

  • 1. Molecular features of the copper binding sites in the octarepeat domain of the prion protein.
    Burns CS; Aronoff-Spencer E; Dunham CM; Lario P; Avdievich NI; Antholine WE; Olmstead MM; Vrielink A; Gerfen GJ; Peisach J; Scott WG; Millhauser GL
    Biochemistry; 2002 Mar; 41(12):3991-4001. PubMed ID: 11900542
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Copper coordination in the full-length, recombinant prion protein.
    Burns CS; Aronoff-Spencer E; Legname G; Prusiner SB; Antholine WE; Gerfen GJ; Peisach J; Millhauser GL
    Biochemistry; 2003 Jun; 42(22):6794-803. PubMed ID: 12779334
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy.
    Aronoff-Spencer E; Burns CS; Avdievich NI; Gerfen GJ; Peisach J; Antholine WE; Ball HL; Cohen FE; Prusiner SB; Millhauser GL
    Biochemistry; 2000 Nov; 39(45):13760-71. PubMed ID: 11076515
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational studies of Cu(II)[peptide] binding motifs: Cu[HGGG] and Cu[HG] as models for Cu(II) binding to the prion protein octarepeat region.
    Pushie MJ; Rauk A
    J Biol Inorg Chem; 2003 Jan; 8(1-2):53-65. PubMed ID: 12459899
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Copper binding to the prion protein: structural implications of four identical cooperative binding sites.
    Viles JH; Cohen FE; Prusiner SB; Goodin DB; Wright PE; Dyson HJ
    Proc Natl Acad Sci U S A; 1999 Mar; 96(5):2042-7. PubMed ID: 10051591
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4.
    Chattopadhyay M; Walter ED; Newell DJ; Jackson PJ; Aronoff-Spencer E; Peisach J; Gerfen GJ; Bennett B; Antholine WE; Millhauser GL
    J Am Chem Soc; 2005 Sep; 127(36):12647-56. PubMed ID: 16144413
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry.
    Whittal RM; Ball HL; Cohen FE; Burlingame AL; Prusiner SB; Baldwin MA
    Protein Sci; 2000 Feb; 9(2):332-43. PubMed ID: 10716185
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The affinity of copper binding to the prion protein octarepeat domain: evidence for negative cooperativity.
    Walter ED; Chattopadhyay M; Millhauser GL
    Biochemistry; 2006 Oct; 45(43):13083-92. PubMed ID: 17059225
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion.
    Giachin G; Mai PT; Tran TH; Salzano G; Benetti F; Migliorati V; Arcovito A; Della Longa S; Mancini G; D'Angelo P; Legname G
    Sci Rep; 2015 Oct; 5():15253. PubMed ID: 26482532
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New insights into metal interactions with the prion protein: EXAFS analysis and structure calculations of copper binding to a single octarepeat from the prion protein.
    McDonald A; Pushie MJ; Millhauser GL; George GN
    J Phys Chem B; 2013 Nov; 117(44):13822-41. PubMed ID: 24102071
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Early onset prion disease from octarepeat expansion correlates with copper binding properties.
    Stevens DJ; Walter ED; Rodríguez A; Draper D; Davies P; Brown DR; Millhauser GL
    PLoS Pathog; 2009 Apr; 5(4):e1000390. PubMed ID: 19381258
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modeling by assembly and molecular dynamics simulations of the low Cu2+ occupancy form of the mammalian prion protein octarepeat region: gaining insight into Cu2+-mediated beta-cleavage.
    Pushie MJ; Vogel HJ
    Biophys J; 2008 Dec; 95(11):5084-91. PubMed ID: 18790846
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Preferential Cu2+ coordination by His96 and His111 induces beta-sheet formation in the unstructured amyloidogenic region of the prion protein.
    Jones CE; Abdelraheim SR; Brown DR; Viles JH
    J Biol Chem; 2004 Jul; 279(31):32018-27. PubMed ID: 15145944
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prion protein selectively binds copper(II) ions.
    Stöckel J; Safar J; Wallace AC; Cohen FE; Prusiner SB
    Biochemistry; 1998 May; 37(20):7185-93. PubMed ID: 9585530
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ab initio simulations of Cu binding sites on the N-terminal region of prion protein.
    Furlan S; La Penna G; Guerrieri F; Morante S; Rossi GC
    J Biol Inorg Chem; 2007 May; 12(4):571-83. PubMed ID: 17333299
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site.
    D'Angelo P; Della Longa S; Arcovito A; Mancini G; Zitolo A; Chillemi G; Giachin G; Legname G; Benetti F
    Biochemistry; 2012 Aug; 51(31):6068-79. PubMed ID: 22788868
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The octapeptide repeats in mammalian prion protein constitute a pH-dependent folding and aggregation site.
    Zahn R
    J Mol Biol; 2003 Nov; 334(3):477-88. PubMed ID: 14623188
    [TBL] [Abstract][Full Text] [Related]  

  • 18. De novo design of a copper(II)-binding helix-turn-helix chimera: the prion octarepeat motif in a new context.
    Shields SB; Franklin SJ
    Biochemistry; 2004 Dec; 43(51):16086-91. PubMed ID: 15610003
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Difference in redox behaviors between copper-binding octarepeat and nonoctarepeat sites in prion protein.
    Yamamoto N; Kuwata K
    J Biol Inorg Chem; 2009 Nov; 14(8):1209-18. PubMed ID: 19585160
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural, EPR superhyperfine, and NMR hyperfine properties of the Cu-octarepeat binding site in the prion protein.
    Ling Y; Khade RL; Zhang Y
    J Phys Chem B; 2011 Mar; 115(11):2663-70. PubMed ID: 21355614
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.