BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

414 related articles for article (PubMed ID: 11901092)

  • 1. Interaction of irinotecan (CPT-11) and its active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38) with human cytochrome P450 enzymes.
    Hanioka N; Ozawa S; Jinno H; Tanaka-Kagawa T; Nishimura T; Ando M; Sawada Ji J
    Drug Metab Dispos; 2002 Apr; 30(4):391-6. PubMed ID: 11901092
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds.
    Nakajima M; Suzuki M; Yamaji R; Takashina H; Shimada N; Yamazaki H; Yokoi T
    Xenobiotica; 1999 Dec; 29(12):1191-202. PubMed ID: 10647906
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
    Wen X; Wang JS; Kivistö KT; Neuvonen PJ; Backman JT
    Br J Clin Pharmacol; 2001 Nov; 52(5):547-53. PubMed ID: 11736863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9.
    Wen X; Wang JS; Backman JT; Kivistö KT; Neuvonen PJ
    Drug Metab Dispos; 2001 Nov; 29(11):1359-61. PubMed ID: 11602509
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes.
    Wen X; Wang JS; Neuvonen PJ; Backman JT
    Eur J Clin Pharmacol; 2002 Jan; 57(11):799-804. PubMed ID: 11868802
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new metabolite of irinotecan in which formation is mediated by human hepatic cytochrome P-450 3A4.
    Sai K; Kaniwa N; Ozawa S; Sawada JI
    Drug Metab Dispos; 2001 Nov; 29(11):1505-13. PubMed ID: 11602529
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism of irinotecan (CPT-11) by CYP3A4 and CYP3A5 in humans.
    Santos A; Zanetta S; Cresteil T; Deroussent A; Pein F; Raymond E; Vernillet L; Risse ML; Boige V; Gouyette A; Vassal G
    Clin Cancer Res; 2000 May; 6(5):2012-20. PubMed ID: 10815927
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition and inactivation of human cytochrome P450 isoforms by phenethyl isothiocyanate.
    Nakajima M; Yoshida R; Shimada N; Yamazaki H; Yokoi T
    Drug Metab Dispos; 2001 Aug; 29(8):1110-3. PubMed ID: 11454729
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: prediction of in vivo drug-drug interactions.
    Katoh M; Nakajima M; Shimada N; Yamazaki H; Yokoi T
    Eur J Clin Pharmacol; 2000; 55(11-12):843-52. PubMed ID: 10805063
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolism of irinotecan (CPT-11) by human hepatic microsomes: participation of cytochrome P-450 3A and drug interactions.
    Haaz MC; Rivory L; Riché C; Vernillet L; Robert J
    Cancer Res; 1998 Feb; 58(3):468-72. PubMed ID: 9458091
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes).
    Palacharla VRC; Chunduru P; Ajjala DR; Bhyrapuneni G; Nirogi R; Li AP
    Drug Metab Dispos; 2019 Oct; 47(10):1032-1039. PubMed ID: 31375472
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biosynthesis of an aminopiperidino metabolite of irinotecan [7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecine] by human hepatic microsomes.
    Haaz MC; Riché C; Rivory LP; Robert J
    Drug Metab Dispos; 1998 Aug; 26(8):769-74. PubMed ID: 9698291
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitory effects of azelastine and its metabolites on drug oxidation catalyzed by human cytochrome P-450 enzymes.
    Nakajima M; Ohyama K; Nakamura S; Shimada N; Yamazaki H; Yokoi T
    Drug Metab Dispos; 1999 Jul; 27(7):792-7. PubMed ID: 10383922
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes.
    Yao HT; Chang YW; Lan SJ; Chen CT; Hsu JT; Yeh TK
    Life Sci; 2006 Nov; 79(26):2432-40. PubMed ID: 16978661
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of coumarin 7-hydroxylase activity in human liver microsomes.
    Draper AJ; Madan A; Parkinson A
    Arch Biochem Biophys; 1997 May; 341(1):47-61. PubMed ID: 9143352
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition selectivity of grapefruit juice components on human cytochromes P450.
    Tassaneeyakul W; Guo LQ; Fukuda K; Ohta T; Yamazoe Y
    Arch Biochem Biophys; 2000 Jun; 378(2):356-63. PubMed ID: 10860553
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro.
    Zhang W; Kilicarslan T; Tyndale RF; Sellers EM
    Drug Metab Dispos; 2001 Jun; 29(6):897-902. PubMed ID: 11353760
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Determination of drug interactions occurring with the metabolic pathways of irinotecan.
    Charasson V; Haaz MC; Robert J
    Drug Metab Dispos; 2002 Jun; 30(6):731-3. PubMed ID: 12019202
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of irsogladine on P450-isoform specific activities in human hepatic microsomes.
    Nakamura A; Tougou K; Kitazumi H; Yamada T; Honjou K; Nonaka K; Mukai H
    Arzneimittelforschung; 2006; 56(7):547-52. PubMed ID: 16927538
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes.
    Kim JH; Kwon SS; Jeong HU; Lee HS
    Int J Mol Sci; 2017 May; 18(5):. PubMed ID: 28468305
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.