BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 11901094)

  • 1. Development of an in vitro screening model for the biosynthesis of acyl glucuronide metabolites and the assessment of their reactivity toward human serum albumin.
    Bolze S; Bromet N; Gay-Feutry C; Massiere F; Boulieu R; Hulot T
    Drug Metab Dispos; 2002 Apr; 30(4):404-13. PubMed ID: 11901094
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Significantly Different Covalent Binding of Oxidative Metabolites, Acyl Glucuronides, and S-Acyl CoA Conjugates Formed from Xenobiotic Carboxylic Acids in Human Liver Microsomes.
    Darnell M; Breitholtz K; Isin EM; Jurva U; Weidolf L
    Chem Res Toxicol; 2015 May; 28(5):886-96. PubMed ID: 25803559
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel approach for predicting acyl glucuronide reactivity via Schiff base formation: development of rapidly formed peptide adducts for LC/MS/MS measurements.
    Wang J; Davis M; Li F; Azam F; Scatina J; Talaat R
    Chem Res Toxicol; 2004 Sep; 17(9):1206-16. PubMed ID: 15377154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acyl glucuronide reactivity in perspective: biological consequences.
    Bailey MJ; Dickinson RG
    Chem Biol Interact; 2003 May; 145(2):117-37. PubMed ID: 12686489
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.
    Walker GS; Atherton J; Bauman J; Kohl C; Lam W; Reily M; Lou Z; Mutlib A
    Chem Res Toxicol; 2007 Jun; 20(6):876-86. PubMed ID: 17536843
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A New Rapid In Vitro Assay for Assessing Reactivity of Acyl Glucuronides.
    Zhong S; Jones R; Lu W; Schadt S; Ottaviani G
    Drug Metab Dispos; 2015 Nov; 43(11):1711-7. PubMed ID: 26276581
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro regioselective stability of beta-1-O- and 2-O-acyl glucuronides of naproxen and their covalent binding to human serum albumin.
    Iwaki M; Ogiso T; Inagawa S; Kakehi K
    J Pharm Sci; 1999 Jan; 88(1):52-7. PubMed ID: 9874702
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acyl glucuronide metabolites: Implications for drug safety assessment.
    Van Vleet TR; Liu H; Lee A; Blomme EAG
    Toxicol Lett; 2017 Apr; 272():1-7. PubMed ID: 28286018
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chemical and immunochemical comparison of protein adduct formation of four carboxylate drugs in rat liver and plasma.
    Bailey MJ; Dickinson RG
    Chem Res Toxicol; 1996; 9(3):659-66. PubMed ID: 8728513
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Predictability of idiosyncratic drug toxicity risk for carboxylic acid-containing drugs based on the chemical stability of acyl glucuronide.
    Sawamura R; Okudaira N; Watanabe K; Murai T; Kobayashi Y; Tachibana M; Ohnuki T; Masuda K; Honma H; Kurihara A; Okazaki O
    Drug Metab Dispos; 2010 Oct; 38(10):1857-64. PubMed ID: 20606003
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Safety Assessment of Acyl Glucuronides-A Simplified Paradigm.
    Smith DA; Hammond T; Baillie TA
    Drug Metab Dispos; 2018 Jun; 46(6):908-912. PubMed ID: 29559442
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of proliferation of HT-29 colon adenocarcinoma cells by carboxylate NSAIDs and their acyl glucuronides.
    Cannell GR; Vesey DA; Dickinson RG
    Life Sci; 2001 Nov; 70(1):37-48. PubMed ID: 11764005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Covalent binding of acidic drugs via reactive intermediates: detection of benoxaprofen and flunoxaprofen protein adducts in biological material.
    Dahms M; Spahn-Langguth H
    Pharmazie; 1996 Nov; 51(11):874-81. PubMed ID: 8985978
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cysteine amide adduct formation from carboxylic acid drugs via UGT-mediated bioactivation in human liver microsomes.
    Harada H; Toyoda Y; Endo T; Kobayashi M
    Pharmazie; 2015 Oct; 70(10):678-83. PubMed ID: 26601426
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro stereoselective degradation of carprofen glucuronide by human serum albumin. Characterization of sites and reactive amino acids.
    Georges H; Presle N; Buronfosse T; Fournel-Gigleux S; Netter P; Magdalou J; Lapicque F
    Chirality; 2000 Feb; 12(2):53-62. PubMed ID: 10637410
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of benoxaprofen and flunoxaprofen acyl glucuronides in covalent binding to rat plasma and liver proteins in vivo.
    Dong JQ; Liu J; Smith PC
    Biochem Pharmacol; 2005 Sep; 70(6):937-48. PubMed ID: 16046212
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HPLC/1H NMR spectroscopic studies of the reactive alpha-1-O-acyl isomer formed during acyl migration of S-naproxen beta-1-O-acyl glucuronide.
    Corcoran O; Mortensen RW; Hansen SH; Troke J; Nicholson JK
    Chem Res Toxicol; 2001 Oct; 14(10):1363-70. PubMed ID: 11599927
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albumin.
    Castillo M; Smith PC
    Drug Metab Dispos; 1995 May; 23(5):566-72. PubMed ID: 7587932
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Acyl glucuronides: the good, the bad and the ugly.
    Regan SL; Maggs JL; Hammond TG; Lambert C; Williams DP; Park BK
    Biopharm Drug Dispos; 2010 Oct; 31(7):367-95. PubMed ID: 20830700
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Studies on the chemical reactivity of 2-phenylpropionic acid 1-O-acyl glucuronide and S-acyl-CoA thioester metabolites.
    Li C; Benet LZ; Grillo MP
    Chem Res Toxicol; 2002 Oct; 15(10):1309-17. PubMed ID: 12387630
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.