386 related articles for article (PubMed ID: 11906281)
1. Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models.
Palomer A; Cabré F; Pascual J; Campos J; Trujillo MA; Entrena A; Gallo MA; García L; Mauleón D; Espinosa A
J Med Chem; 2002 Mar; 45(7):1402-11. PubMed ID: 11906281
[TBL] [Abstract][Full Text] [Related]
2. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
Riendeau D; Percival MD; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Falgueyret JP; Ford-Hutchinson AW; Gordon R; Greig G; Gresser M; Guay J; Kargman S; Léger S; Mancini JA; O'Neill G; Ouellet M; Rodger IW; Thérien M; Wang Z; Webb JK; Wong E; Chan CC
Br J Pharmacol; 1997 May; 121(1):105-17. PubMed ID: 9146894
[TBL] [Abstract][Full Text] [Related]
3. Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation.
Pinheiro RM; Calixto JB
Inflamm Res; 2002 Dec; 51(12):603-10. PubMed ID: 12558194
[TBL] [Abstract][Full Text] [Related]
4. Design and synthesis of celecoxib and rofecoxib analogues as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of sulfonamide and methylsulfonyl pharmacophores by an azido bioisostere.
Habeeb AG; Praveen Rao PN; Knaus EE
J Med Chem; 2001 Aug; 44(18):3039-42. PubMed ID: 11520213
[TBL] [Abstract][Full Text] [Related]
5. A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin.
Ouellet M; Riendeau D; Percival MD
Proc Natl Acad Sci U S A; 2001 Dec; 98(25):14583-8. PubMed ID: 11717412
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.
Praveen Rao PN; Amini M; Li H; Habeeb AG; Knaus EE
J Med Chem; 2003 Nov; 46(23):4872-82. PubMed ID: 14584938
[TBL] [Abstract][Full Text] [Related]
7. Involvement of cyclooxygenase-derived prostaglandin E2 and nitric oxide in the protection of rat pancreas afforded by low dose of lipopolysaccharide.
Jaworek J; Bonior J; Tomaszewska R; Jachimczak B; Kot M; Bielański W; Pawlik WW; Sendur R; Stachura J; Konturek PC; Konturek SJ
J Physiol Pharmacol; 2001 Mar; 52(1):107-26. PubMed ID: 11321505
[TBL] [Abstract][Full Text] [Related]
8. Up-regulation of cyclooxygenase-2 by inhibition of cyclooxygenase-1: a key to nonsteroidal anti-inflammatory drug-induced intestinal damage.
Tanaka A; Hase S; Miyazawa T; Takeuchi K
J Pharmacol Exp Ther; 2002 Mar; 300(3):754-61. PubMed ID: 11861778
[TBL] [Abstract][Full Text] [Related]
9. Up-regulation of COX-2 by inhibition of COX-1 in the rat: a key to NSAID-induced gastric injury.
Tanaka A; Araki H; Hase S; Komoike Y; Takeuchi K
Aliment Pharmacol Ther; 2002 Apr; 16 Suppl 2():90-101. PubMed ID: 11966529
[TBL] [Abstract][Full Text] [Related]
10. Cyclooxygenase-2, player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells.
Song X; Lin HP; Johnson AJ; Tseng PH; Yang YT; Kulp SK; Chen CS
J Natl Cancer Inst; 2002 Apr; 94(8):585-91. PubMed ID: 11959891
[TBL] [Abstract][Full Text] [Related]
11. Cyclooxygenase-1 vs. cyclooxygenase-2 inhibitors in the induction of antinociception in rodent withdrawal reflexes.
Mazario J; Gaitan G; Herrero JF
Neuropharmacology; 2001 Jun; 40(7):937-46. PubMed ID: 11378164
[TBL] [Abstract][Full Text] [Related]
12. COX-2-Specific inhibitors--the emergence of a new class of analgesic and anti-inflammatory drugs.
Everts B; Währborg P; Hedner T
Clin Rheumatol; 2000; 19(5):331-43. PubMed ID: 11055820
[TBL] [Abstract][Full Text] [Related]
13. Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors.
Kalgutkar AS; Marnett AB; Crews BC; Remmel RP; Marnett LJ
J Med Chem; 2000 Jul; 43(15):2860-70. PubMed ID: 10956194
[TBL] [Abstract][Full Text] [Related]
14. Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.
Weber A; Casini A; Heine A; Kuhn D; Supuran CT; Scozzafava A; Klebe G
J Med Chem; 2004 Jan; 47(3):550-7. PubMed ID: 14736236
[TBL] [Abstract][Full Text] [Related]
15. NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2.
Wallace JL; McKnight W; Reuter BK; Vergnolle N
Gastroenterology; 2000 Sep; 119(3):706-14. PubMed ID: 10982765
[TBL] [Abstract][Full Text] [Related]
16. The new COX-2 inhibitors: rofecoxib (Vioxx) and celecoxib (Celebrex).
Wynn RL
Gen Dent; 2000; 48(1):16-20. PubMed ID: 11199547
[No Abstract] [Full Text] [Related]
17. [Specific inhibitors of cyclooxygenase-2 (COX-2): current knowledge and perspectives].
Rioda WT; Nervetti A
Acta Biomed Ateneo Parmense; 2001; 72(3-4):55-64. PubMed ID: 11889908
[TBL] [Abstract][Full Text] [Related]
18. Structure-based design of cyclooxygenase-2 selectivity into ketoprofen.
Palomer A; Pascual J; Cabré M; Borràs L; González G; Aparici M; Carabaza A; Cabré F; García ML; Mauleón D
Bioorg Med Chem Lett; 2002 Feb; 12(4):533-7. PubMed ID: 11844666
[TBL] [Abstract][Full Text] [Related]
19. [Selective cyclooxygenase 2 inhibitors (COX-2)].
Mejza F; Nizankowska E
Postepy Hig Med Dosw; 2001; 55(2):287-302. PubMed ID: 11468975
[TBL] [Abstract][Full Text] [Related]
20. COX-2 inhibitors.
Hawkey CJ
Lancet; 1999 Jan; 353(9149):307-14. PubMed ID: 9929039
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
