BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 11909939)

  • 1. Mutation of mouse p53 Ser23 and the response to DNA damage.
    Wu Z; Earle J; Saito S; Anderson CW; Appella E; Xu Y
    Mol Cell Biol; 2002 Apr; 22(8):2441-9. PubMed ID: 11909939
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.
    Unger T; Juven-Gershon T; Moallem E; Berger M; Vogt Sionov R; Lozano G; Oren M; Haupt Y
    EMBO J; 1999 Apr; 18(7):1805-14. PubMed ID: 10202144
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA damage-induced phosphorylation of p53 at serine 20 correlates with p21 and Mdm-2 induction in vivo.
    Jabbur JR; Huang P; Zhang W
    Oncogene; 2000 Dec; 19(54):6203-8. PubMed ID: 11175334
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhancement of the antiproliferative function of p53 by phosphorylation at serine 20: an inference from site-directed mutagenesis studies.
    Jabbur JR; Huang P; Zhang W
    Int J Mol Med; 2001 Feb; 7(2):163-8. PubMed ID: 11172619
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
    Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
    Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage.
    Chehab NH; Malikzay A; Stavridi ES; Halazonetis TD
    Proc Natl Acad Sci U S A; 1999 Nov; 96(24):13777-82. PubMed ID: 10570149
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.
    Okamoto K; Kashima K; Pereg Y; Ishida M; Yamazaki S; Nota A; Teunisse A; Migliorini D; Kitabayashi I; Marine JC; Prives C; Shiloh Y; Jochemsen AG; Taya Y
    Mol Cell Biol; 2005 Nov; 25(21):9608-20. PubMed ID: 16227609
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Defective p53 post-translational modification required for wild type p53 inactivation in malignant epithelial cells with mdm2 gene amplification.
    Knights CD; Liu Y; Appella E; Kulesz-Martin M
    J Biol Chem; 2003 Dec; 278(52):52890-900. PubMed ID: 14555661
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover.
    Dumaz N; Milne DM; Jardine LJ; Meek DW
    Biochem J; 2001 Oct; 359(Pt 2):459-64. PubMed ID: 11583595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.
    Iwakuma T; Parant JM; Fasulo M; Zwart E; Jacks T; de Vries A; Lozano G
    Oncogene; 2004 Oct; 23(46):7644-50. PubMed ID: 15361844
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of serine 18 regulates distinct p53 functions in mice.
    Sluss HK; Armata H; Gallant J; Jones SN
    Mol Cell Biol; 2004 Feb; 24(3):976-84. PubMed ID: 14729946
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage.
    Chao C; Saito S; Kang J; Anderson CW; Appella E; Xu Y
    EMBO J; 2000 Sep; 19(18):4967-75. PubMed ID: 10990460
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at serine 15 or 20 or MDM2 binding.
    Wang W; Takimoto R; Rastinejad F; El-Deiry WS
    Mol Cell Biol; 2003 Mar; 23(6):2171-81. PubMed ID: 12612087
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphorylation of murine p53 at ser-18 regulates the p53 responses to DNA damage.
    Chao C; Saito S; Anderson CW; Appella E; Xu Y
    Proc Natl Acad Sci U S A; 2000 Oct; 97(22):11936-41. PubMed ID: 11035798
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
    Hirao A; Kong YY; Matsuoka S; Wakeham A; Ruland J; Yoshida H; Liu D; Elledge SJ; Mak TW
    Science; 2000 Mar; 287(5459):1824-7. PubMed ID: 10710310
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.
    MacPherson D; Kim J; Kim T; Rhee BK; Van Oostrom CT; DiTullio RA; Venere M; Halazonetis TD; Bronson R; De Vries A; Fleming M; Jacks T
    EMBO J; 2004 Sep; 23(18):3689-99. PubMed ID: 15343266
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation.
    Zhang Y; Xiong Y
    Science; 2001 Jun; 292(5523):1910-5. PubMed ID: 11397945
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1/2 MAP kinase.
    Melnikova VO; Santamaria AB; Bolshakov SV; Ananthaswamy HN
    Oncogene; 2003 Sep; 22(38):5958-66. PubMed ID: 12955074
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA damage induces phosphorylation of the amino terminus of p53.
    Siliciano JD; Canman CE; Taya Y; Sakaguchi K; Appella E; Kastan MB
    Genes Dev; 1997 Dec; 11(24):3471-81. PubMed ID: 9407038
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation.
    de Toledo SM; Azzam EI; Dahlberg WK; Gooding TB; Little JB
    Oncogene; 2000 Dec; 19(54):6185-93. PubMed ID: 11175332
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.