BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

83 related articles for article (PubMed ID: 11916138)

  • 1. Quantitative structure-activity relationship study of novel alpha1a-selective adrenoceptor antagonists.
    Singh P; Kumar R
    J Enzyme Inhib; 2001 Oct; 16(4):331-8. PubMed ID: 11916138
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacophore-based design, synthesis, biological evaluation, and 3D-QSAR studies of aryl-piperazines as alpha(1)-adrenoceptor antagonists.
    Li MY; Fang H; Xia L
    Bioorg Med Chem Lett; 2005 Jul; 15(13):3216-9. PubMed ID: 15935663
    [TBL] [Abstract][Full Text] [Related]  

  • 3. QSAR analyses of 3-(4-benzylpiperidin-1-yl)-N-phenylpropylamine derivatives as potent CCR5 antagonists.
    Roy K; Leonard JT
    J Chem Inf Model; 2005; 45(5):1352-68. PubMed ID: 16180912
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
    Kolhatkar RB; Ghorai SK; George C; Reith ME; Dutta AK
    J Med Chem; 2003 May; 46(11):2205-15. PubMed ID: 12747792
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Design, synthesis and vasorelaxant activity of R, S-1-(substituted phenyl)-4-[3-(naphtha-1-yl-oxy)-2-hydroxypropyl]-piperazine derivatives].
    Fu XZ; Tang L; Yuan M; Shi JS
    Yao Xue Xue Bao; 2007 Jul; 42(7):735-40. PubMed ID: 17882957
    [TBL] [Abstract][Full Text] [Related]  

  • 6. (Phenylpiperidinyl)cyclohexylsulfonamides: development of alpha1a/1d-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).
    Chiu G; Li S; Connolly PJ; Pulito V; Liu J; Middleton SA
    Bioorg Med Chem Lett; 2007 Jul; 17(14):3930-4. PubMed ID: 17517507
    [TBL] [Abstract][Full Text] [Related]  

  • 7. QSAR study for a novel series of ortho disubstituted phenoxy analogues of alpha1-adrenoceptor antagonist WB4101.
    Pallavicini M; Fumagalli L; Gobbi M; Bolchi C; Colleoni S; Moroni B; Pedretti A; Rusconi C; Vistoli G; Valoti E
    Eur J Med Chem; 2006 Sep; 41(9):1025-40. PubMed ID: 16737760
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantitative structure-activity relationship study of new potent and selective antagonists at the 5-HT(1A) and adrenergic alpha(1d) receptors: Derivatives of spiroethyl phenyl(substituted)piperazine.
    Sharma BK; Singh P; Sharma S
    J Enzyme Inhib Med Chem; 2006 Oct; 21(5):601-7. PubMed ID: 17194034
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
    Bojarski AJ; Paluchowska MH; Duszyńska B; Kłodzińska A; Tatarczyńska E; Chojnacka-Wójcik E
    Bioorg Med Chem; 2005 Mar; 13(6):2293-303. PubMed ID: 15727878
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies.
    Mor M; Rivara S; Lodola A; Plazzi PV; Tarzia G; Duranti A; Tontini A; Piersanti G; Kathuria S; Piomelli D
    J Med Chem; 2004 Oct; 47(21):4998-5008. PubMed ID: 15456244
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Computational study of antagonist/alpha1A adrenoceptor complexes--observations of conformational variations on the formation of ligand/receptor complexes.
    Kinsella GK; Rozas I; Watson GW
    J Med Chem; 2006 Jan; 49(2):501-10. PubMed ID: 16420037
    [TBL] [Abstract][Full Text] [Related]  

  • 12. (Phenylpiperazinyl)cyclohexylureas: discovery of alpha1a/1d-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).
    Chiu G; Li S; Connolly PJ; Pulito V; Liu J; Middleton SA
    Bioorg Med Chem Lett; 2008 Jan; 18(2):640-4. PubMed ID: 18055202
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potent 4-aryl- or 4-arylalkyl-substituted 3-isoxazolol GABA(A) antagonists: synthesis, pharmacology, and molecular modeling.
    Frølund B; Jensen LS; Guandalini L; Canillo C; Vestergaard HT; Kristiansen U; Nielsen B; Stensbøl TB; Madsen C; Krogsgaard-Larsen P; Liljefors T
    J Med Chem; 2005 Jan; 48(2):427-39. PubMed ID: 15658856
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, alpha 1-adrenoceptor antagonist activity, and SAR study of novel arylpiperazine derivatives of phenytoin.
    Handzlik J; Maciag D; Kubacka M; Mogilski S; Filipek B; Stadnicka K; Kieć-Kononowicz K
    Bioorg Med Chem; 2008 Jun; 16(11):5982-98. PubMed ID: 18490167
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of alpha1-adrenoceptor subtype mRNA as a predictor of the efficacy of subtype selective alpha1-adrenoceptor antagonists in the management of benign prostatic hyperplasia.
    Kojima Y; Sasaki S; Kubota Y; Hayase M; Hayashi Y; Shinoura H; Tsujimoto G; Kohri K
    J Urol; 2008 Mar; 179(3):1040-6. PubMed ID: 18206918
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of new non-imidazole H3-receptor antagonists of the 2-aminobenzimidazole series.
    Rivara M; Zuliani V; Cocconcelli G; Morini G; Comini M; Rivara S; Mor M; Bordi F; Barocelli E; Ballabeni V; Bertoni S; Plazzi PV
    Bioorg Med Chem; 2006 Mar; 14(5):1413-24. PubMed ID: 16263297
    [TBL] [Abstract][Full Text] [Related]  

  • 17. (Arylpiperazinyl)cyclohexylsufonamides: discovery of alpha(1a/1d)-selective adrenergic receptor antagonists for the treatment of Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms (BPH/LUTS).
    Chiu G; Li S; Connolly PJ; Pulito V; Liu J; Middleton SA
    Bioorg Med Chem Lett; 2007 Jun; 17(12):3292-7. PubMed ID: 17452102
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RBx 6198: a novel alpha1-adrenoceptor antagonist for the treatment of benign prostatic hyperplasia.
    Nanda K; Naruganahalli KS; Gupta S; Malhotra S; Tiwari A; Hegde LG; Jain S; Sinha N; Gupta JB; Chugh A; Anand N; Ray A
    Eur J Pharmacol; 2009 Apr; 607(1-3):213-9. PubMed ID: 19239913
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alpha(1) adrenoceptor subtype selectivity. 3D-QSAR models for a new class of alpha(1) adrenoceptor antagonists derived from the novel antipsychotic sertindole.
    Balle T; Andersen K; Søby KK; Liljefors T
    J Mol Graph Model; 2003 Jun; 21(6):523-34. PubMed ID: 12676239
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors.
    López-Rodríguez ML; Morcillo MJ; Fernández E; Benhamú B; Tejada I; Ayala D; Viso A; Campillo M; Pardo L; Delgado M; Manzanares J; Fuentes JA
    J Med Chem; 2005 Apr; 48(7):2548-58. PubMed ID: 15801844
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.