These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

108 related articles for article (PubMed ID: 11922834)

  • 1. Homology modeling of falcipain-2: validation, de novo ligand design and synthesis of novel inhibitors.
    Sabnis Y; Rosenthal PJ; Desai P; Avery MA
    J Biomol Struct Dyn; 2002 Apr; 19(5):765-74. PubMed ID: 11922834
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Probing the structure of falcipain-3, a cysteine protease from Plasmodium falciparum: comparative protein modeling and docking studies.
    Sabnis YA; Desai PV; Rosenthal PJ; Avery MA
    Protein Sci; 2003 Mar; 12(3):501-9. PubMed ID: 12592020
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Plasmodium falciparum: biochemical characterization of the cysteine protease falcipain-2'.
    Singh N; Sijwali PS; Pandey KC; Rosenthal PJ
    Exp Parasitol; 2006 Mar; 112(3):187-92. PubMed ID: 16337629
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural features of falcipain-3 inhibitors: an in silico study.
    Wang J; Li F; Li Y; Yang Y; Zhang S; Yang L
    Mol Biosyst; 2013 Sep; 9(9):2296-310. PubMed ID: 23765034
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural characterization of vivapain-2 and vivapain-3, cysteine proteases from Plasmodium vivax: comparative protein modeling and docking studies.
    Desai PV; Avery MA
    J Biomol Struct Dyn; 2004 Jun; 21(6):781-90. PubMed ID: 15107000
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors.
    Verissimo E; Berry N; Gibbons P; Cristiano ML; Rosenthal PJ; Gut J; Ward SA; O'Neill PM
    Bioorg Med Chem Lett; 2008 Jul; 18(14):4210-4. PubMed ID: 18554905
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database.
    Desai PV; Patny A; Sabnis Y; Tekwani B; Gut J; Rosenthal P; Srivastava A; Avery M
    J Med Chem; 2004 Dec; 47(26):6609-15. PubMed ID: 15588096
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of novel parasitic cysteine protease inhibitors by use of virtual screening. 2. The available chemical directory.
    Desai PV; Patny A; Gut J; Rosenthal PJ; Tekwani B; Srivastava A; Avery M
    J Med Chem; 2006 Mar; 49(5):1576-84. PubMed ID: 16509575
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of protein-protein interaction mimics as Plasmodium falciparum cysteine protease, falcipain-2 inhibitors.
    Rizzi L; Sundararaman S; Cendic K; Vaiana N; Korde R; Sinha D; Mohmmed A; Malhotra P; Romeo S
    Eur J Med Chem; 2011 Jun; 46(6):2083-90. PubMed ID: 21429631
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of novel malarial cysteine protease inhibitors using structure-based virtual screening of a focused cysteine protease inhibitor library.
    Shah F; Mukherjee P; Gut J; Legac J; Rosenthal PJ; Tekwani BL; Avery MA
    J Chem Inf Model; 2011 Apr; 51(4):852-64. PubMed ID: 21428453
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors.
    Micale N; Ettari R; Schirmeister T; Evers A; Gelhaus C; Leippe M; Zappalà M; Grasso S
    Bioorg Med Chem; 2009 Sep; 17(18):6505-11. PubMed ID: 19709887
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Allosteric regulation of the Plasmodium falciparum cysteine protease falcipain-2 by heme.
    Marques AF; Gomes PS; Oliveira PL; Rosenthal PJ; Pascutti PG; Lima LM
    Arch Biochem Biophys; 2015 May; 573():92-9. PubMed ID: 25791019
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium.
    Hansen G; Heitmann A; Witt T; Li H; Jiang H; Shen X; Heussler VT; Rennenberg A; Hilgenfeld R
    Structure; 2011 Jul; 19(7):919-29. PubMed ID: 21742259
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selected gold compounds cause pronounced inhibition of Falcipain 2 and effectively block P. falciparum growth in vitro.
    Micale N; Cinellu MA; Maiore L; Sannella AR; Severini C; Schirmeister T; Gabbiani C; Messori L
    J Inorg Biochem; 2011 Dec; 105(12):1576-9. PubMed ID: 22071081
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selection of cysteine protease inhibitor-resistant malaria parasites is accompanied by amplification of falcipain genes and alteration in inhibitor transport.
    Singh A; Rosenthal PJ
    J Biol Chem; 2004 Aug; 279(34):35236-41. PubMed ID: 15192087
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Computation-based virtual screening for designing novel antimalarial drugs by targeting falcipain-III: a structure-based drug designing approach.
    Kesharwani RK; Singh DV; Misra K
    J Vector Borne Dis; 2013; 50(2):93-102. PubMed ID: 23995310
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A chimeric cysteine protease of Plasmodium berghei engineered to resemble the Plasmodium falciparum protease falcipain-2.
    Singh A; Walker KJ; Sijwali PS; Lau AL; Rosenthal PJ
    Protein Eng Des Sel; 2007 Apr; 20(4):171-7. PubMed ID: 17430972
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and antimalarial effects of phenothiazine inhibitors of a Plasmodium falciparum cysteine protease.
    Domínguez JN; López S; Charris J; Iarruso L; Lobo G; Semenov A; Olson JE; Rosenthal PJ
    J Med Chem; 1997 Aug; 40(17):2726-32. PubMed ID: 9276017
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cysteine proteases of malaria parasites.
    Rosenthal PJ
    Int J Parasitol; 2004 Dec; 34(13-14):1489-99. PubMed ID: 15582526
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Homology modeling and mutagenesis analyses of Plasmodium falciparum falcipain 2A: implications for rational drug design.
    Goh LL; Sim TS
    Biochem Biophys Res Commun; 2004 Oct; 323(2):565-72. PubMed ID: 15369788
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.