BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 11927604)

  • 1. The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites.
    Silke J; Hawkins CJ; Ekert PG; Chew J; Day CL; Pakusch M; Verhagen AM; Vaux DL
    J Cell Biol; 2002 Apr; 157(1):115-24. PubMed ID: 11927604
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.
    Silke J; Ekert PG; Day CL; Hawkins CJ; Baca M; Chew J; Pakusch M; Verhagen AM; Vaux DL
    EMBO J; 2001 Jun; 20(12):3114-23. PubMed ID: 11406588
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria.
    Zhang XD; Zhang XY; Gray CP; Nguyen T; Hersey P
    Cancer Res; 2001 Oct; 61(19):7339-48. PubMed ID: 11585775
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia.
    Saito A; Hayashi T; Okuno S; Ferrand-Drake M; Chan PH
    J Cereb Blood Flow Metab; 2003 Sep; 23(9):1010-9. PubMed ID: 12973017
    [TBL] [Abstract][Full Text] [Related]  

  • 5. X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO.
    Morizane Y; Honda R; Fukami K; Yasuda H
    J Biochem; 2005 Feb; 137(2):125-32. PubMed ID: 15749826
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substrate cleavage by caspases generates protein fragments with Smac/Diablo-like activities.
    Hell K; Saleh M; Crescenzo GD; O'Connor-McCourt MD; Nicholson DW
    Cell Death Differ; 2003 Nov; 10(11):1234-9. PubMed ID: 14576775
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.
    Srinivasula SM; Hegde R; Saleh A; Datta P; Shiozaki E; Chai J; Lee RA; Robbins PD; Fernandes-Alnemri T; Shi Y; Alnemri ES
    Nature; 2001 Mar; 410(6824):112-6. PubMed ID: 11242052
    [TBL] [Abstract][Full Text] [Related]  

  • 8. XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.
    Bratton SB; Lewis J; Butterworth M; Duckett CS; Cohen GM
    Cell Death Differ; 2002 Sep; 9(9):881-92. PubMed ID: 12181739
    [TBL] [Abstract][Full Text] [Related]  

  • 9. X-linked inhibitor regulating TRAIL-induced apoptosis in chemoresistant human primary glioblastoma cells.
    Roa WH; Chen H; Fulton D; Gulavita S; Shaw A; Th'ng J; Farr-Jones M; Moore R; Petruk K
    Clin Invest Med; 2003 Oct; 26(5):231-42. PubMed ID: 14596484
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Upstream regulatory role for XIAP in receptor-mediated apoptosis.
    Wilkinson JC; Cepero E; Boise LH; Duckett CS
    Mol Cell Biol; 2004 Aug; 24(16):7003-14. PubMed ID: 15282301
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein.
    Fu J; Jin Y; Arend LJ
    J Biol Chem; 2003 Dec; 278(52):52660-72. PubMed ID: 14523016
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis.
    Yang QH; Church-Hajduk R; Ren J; Newton ML; Du C
    Genes Dev; 2003 Jun; 17(12):1487-96. PubMed ID: 12815069
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of XIAP and Smac/DIABLO in the rat hippocampus following transient forebrain ischemia.
    Siegelin MD; Kossatz LS; Winckler J; Rami A
    Neurochem Int; 2005 Jan; 46(1):41-51. PubMed ID: 15567514
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.
    Vucic D; Franklin MC; Wallweber HJ; Das K; Eckelman BP; Shin H; Elliott LO; Kadkhodayan S; Deshayes K; Salvesen GS; Fairbrother WJ
    Biochem J; 2005 Jan; 385(Pt 1):11-20. PubMed ID: 15485396
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways.
    Suzuki Y; Takahashi-Niki K; Akagi T; Hashikawa T; Takahashi R
    Cell Death Differ; 2004 Feb; 11(2):208-16. PubMed ID: 14605674
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Opposite regulation of XIAP and Smac/DIABLO in the rat endometrium in response to 17beta-estradiol at estrus.
    Leblanc V; Dery MC; Shooner C; Asselin E
    Reprod Biol Endocrinol; 2003 Aug; 1():59. PubMed ID: 12967350
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria.
    Zhang XD; Borrow JM; Zhang XY; Nguyen T; Hersey P
    Oncogene; 2003 May; 22(19):2869-81. PubMed ID: 12771938
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.
    Checinska A; Hoogeland BS; Rodriguez JA; Giaccone G; Kruyt FA
    Exp Cell Res; 2007 Apr; 313(6):1215-24. PubMed ID: 17291493
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo.
    Gao Z; Tian Y; Wang J; Yin Q; Wu H; Li YM; Jiang X
    J Biol Chem; 2007 Oct; 282(42):30718-27. PubMed ID: 17724022
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Unlike Diablo/smac, Grim promotes global ubiquitination and specific degradation of X chromosome-linked inhibitor of apoptosis (XIAP) and neither cause apoptosis.
    Silke J; Kratina T; Ekert PG; Pakusch M; Vaux DL
    J Biol Chem; 2004 Feb; 279(6):4313-21. PubMed ID: 14570909
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.