BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 11931840)

  • 1. Relative importance of maternal and embryonic microsomal epoxide hydrolase in 7,12-dimethylbenz[a]anthracene-induced developmental toxicity.
    Miyata M; Motoki K; Tamura E; Furukawa M; Gonzalez FJ; Yamazoe Y
    Biochem Pharmacol; 2002 Mar; 63(6):1077-84. PubMed ID: 11931840
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene.
    Miyata M; Kudo G; Lee YH; Yang TJ; Gelboin HV; Fernandez-Salguero P; Kimura S; Gonzalez FJ
    J Biol Chem; 1999 Aug; 274(34):23963-8. PubMed ID: 10446164
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Microsomal expoxide hydrolase is required for 7,12-dimethylbenz[a]anthracene (DMBA)-induced immunotoxicity in mice.
    Gao J; Lauer FT; Mitchell LA; Burchiel SW
    Toxicol Sci; 2007 Jul; 98(1):137-44. PubMed ID: 17442664
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of 7,12-dimethylbenz[a]anthracene-induced immunotoxicity: role of metabolic activation at the target organ.
    Miyata M; Furukawa M; Takahashi K; Gonzalez FJ; Yamazoe Y
    Jpn J Pharmacol; 2001 Jul; 86(3):302-9. PubMed ID: 11488430
    [TBL] [Abstract][Full Text] [Related]  

  • 5. involvement of microsomal epoxide hydrolase enzyme in ovotoxicity caused by 7,12-dimethylbenz[a]anthracene.
    Rajapaksa KS; Sipes IG; Hoyer PB
    Toxicol Sci; 2007 Apr; 96(2):327-34. PubMed ID: 17204581
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of ovotoxicity induced by 7, 12-dimethylbenz[a]anthracene and its 3,4-diol metabolite utilizing a rat in vitro ovarian culture system.
    Igawa Y; Keating AF; Rajapaksa KS; Sipes IG; Hoyer PB
    Toxicol Appl Pharmacol; 2009 Feb; 234(3):361-9. PubMed ID: 19027032
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure.
    Keating AF; Rajapaksa KS; Sipes IG; Hoyer PB
    Toxicol Sci; 2008 Oct; 105(2):351-9. PubMed ID: 18622027
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mouse endometrium stromal cells express a polycyclic aromatic hydrocarbon-inducible cytochrome P450 that closely resembles the novel P450 in mouse embryo fibroblasts (P450EF).
    Savas U; Christou M; Jefcoate CR
    Carcinogenesis; 1993 Oct; 14(10):2013-8. PubMed ID: 8222047
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Functional analysis of drug metabolizing enzymes using gene knockout animals].
    Miyata M
    Yakugaku Zasshi; 2003 Jul; 123(7):569-76. PubMed ID: 12875239
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p53 and ATM/ATR regulate 7,12-dimethylbenz[a]anthracene-induced immunosuppression.
    Gao J; Mitchell LA; Lauer FT; Burchiel SW
    Mol Pharmacol; 2008 Jan; 73(1):137-46. PubMed ID: 17925458
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Variation in route of microsomal activation of 7,12-dimethylbenz [a]anthracene with substrate concentration +.
    Bigger CA; Tomaszewski JE; Dipple A
    Carcinogenesis; 1980 Jan; 1(1):15-20. PubMed ID: 22282975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Covalent binding of 7,12-dimethylbenz(a)anthracene and 10-fluoro-7,12-dimethylbenz(a)anthracene to mouse epidermal DNA and its relationship to tumor-initiating activity.
    DiGiovanni J; Fisher EP; Aalfs KK; Prichett WP
    Cancer Res; 1985 Feb; 45(2):591-7. PubMed ID: 3917851
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of rat liver microsomal epoxide hydrolase by thiazole and pyrazine: hydrolysis of 2-cyanoethylene oxide.
    Kim SG; Kedderis GL; Batra R; Novak RF
    Carcinogenesis; 1993 Aug; 14(8):1665-70. PubMed ID: 7689039
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Resolution and absolute configuration of 7,12-dimethylbenz[a]anthracene 5,6-epoxide enantiomers.
    Mushtaq M; Weems HB; Yang SK
    Biochem Biophys Res Commun; 1984 Dec; 125(2):539-45. PubMed ID: 6440560
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Influence of beta-naphthoflavone on 7,12-dimethylbenz(a)anthracene metabolism, DNA adduction, and tumorigenicity in rainbow trout.
    Weimer TL; Reddy AP; Harttig U; Alexander D; Stamm SC; Miller MR; Baird W; Hendricks J; Bailey G
    Toxicol Sci; 2000 Oct; 57(2):217-28. PubMed ID: 11006352
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison of metabolism-mediated binding to DNA of 7-hydroxymethyl-12-methylbenz(a)anthracene and 7, 12-dimethylbenz(a)anthracene.
    Dipple A; Tomaszewski JE; Moschel RC; Bigger CA; Nebzydoski JA; Egan M
    Cancer Res; 1979 Apr; 39(4):1154-8. PubMed ID: 105803
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity.
    Buters J; Quintanilla-Martinez L; Schober W; Soballa VJ; Hintermair J; Wolff T; Gonzalez FJ; Greim H
    Carcinogenesis; 2003 Feb; 24(2):327-34. PubMed ID: 12584184
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Correlation between formation of a specific hydrocarbon-deoxyribonucleoside adduct and tumor-initiating activity of 7,12-dimethylbenz(a)anthracene and its 9- and 10-monofluoroderivatives in mice.
    DiGiovanni J; Sawyer TW; Fisher EP
    Cancer Res; 1986 Sep; 46(9):4336-41. PubMed ID: 3089589
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P450 1B1 is required for 7,12-dimethylbenz(a)-anthracene (DMBA) induced spleen cell immunotoxicity.
    Gao J; Lauer FT; Dunaway S; Burchiel SW
    Toxicol Sci; 2005 Jul; 86(1):68-74. PubMed ID: 15843505
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Both (+/-)syn- and (+/-)anti-7,12-dimethylbenz[a]anthracene-3,4-diol-1,2-epoxides initiate tumors in mouse skin that possess -CAA- to -CTA- mutations at Codon 61 of c-H-ras.
    Tang MS; Vulimiri SV; Viaje A; Chen JX; Bilolikar DS; Morris RJ; Harvey RG; Slaga TJ; DiGiovanni J
    Cancer Res; 2000 Oct; 60(20):5688-95. PubMed ID: 11059761
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.