BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 11943860)

  • 1. Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues.
    Nekhaeva E; Bodyak ND; Kraytsberg Y; McGrath SB; Van Orsouw NJ; Pluzhnikov A; Wei JY; Vijg J; Khrapko K
    Proc Natl Acad Sci U S A; 2002 Apr; 99(8):5521-6. PubMed ID: 11943860
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms.
    Coller HA; Bodyak ND; Khrapko K
    Ann N Y Acad Sci; 2002 Apr; 959():434-47. PubMed ID: 11976216
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MtDNA point mutations are associated with deletion mutations in aged rat.
    Pak JW; Vang F; Johnson C; McKenzie D; Aiken JM
    Exp Gerontol; 2005 Mar; 40(3):209-18. PubMed ID: 15763398
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential occurrence of mutations in mitochondrial DNA of human skeletal muscle during aging.
    Zhang C; Liu VW; Addessi CL; Sheffield DA; Linnane AW; Nagley P
    Hum Mutat; 1998; 11(5):360-71. PubMed ID: 9600454
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial DNA deletions and the aging heart.
    Mohamed SA; Hanke T; Erasmi AW; Bechtel MJ; Scharfschwerdt M; Meissner C; Sievers HH; Gosslau A
    Exp Gerontol; 2006 May; 41(5):508-17. PubMed ID: 16632292
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutations in mitochondrial DNA accumulate differentially in three different human tissues during ageing.
    Liu VW; Zhang C; Nagley P
    Nucleic Acids Res; 1998 Mar; 26(5):1268-75. PubMed ID: 9469836
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection.
    Coller HA; Khrapko K; Bodyak ND; Nekhaeva E; Herrero-Jimenez P; Thilly WG
    Nat Genet; 2001 Jun; 28(2):147-50. PubMed ID: 11381261
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing.
    Greaves LC; Nooteboom M; Elson JL; Tuppen HA; Taylor GA; Commane DM; Arasaradnam RP; Khrapko K; Taylor RW; Kirkwood TB; Mathers JC; Turnbull DM
    PLoS Genet; 2014 Sep; 10(9):e1004620. PubMed ID: 25232829
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The low abundance of clonally expanded mitochondrial DNA point mutations in aged substantia nigra neurons.
    Reeve AK; Krishnan KJ; Taylor G; Elson JL; Bender A; Taylor RW; Morris CM; Turnbull DM
    Aging Cell; 2009 Aug; 8(4):496-8. PubMed ID: 19489744
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Detection of the ageing-associated 5-Kb common deletion of mitochondrial DNA in blood and bone marrow of hematologically normal adults. Absence of the deletion in clonal bone marrow disorders.
    Gattermann N; Berneburg M; Heinisch J; Aul C; Schneider W
    Leukemia; 1995 Oct; 9(10):1704-10. PubMed ID: 7564514
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quantification and sequencing of somatic deleted mtDNA in single cells: evidence for partially duplicated mtDNA in aged human tissues.
    Bodyak ND; Nekhaeva E; Wei JY; Khrapko K
    Hum Mol Genet; 2001 Jan; 10(1):17-24. PubMed ID: 11136709
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Independent occurrence of somatic mutations in mitochondrial DNA of human skin from subjects of various ages.
    Liu VW; Zhang C; Pang CY; Lee HC; Lu CY; Wei YH; Nagley P
    Hum Mutat; 1998; 11(3):191-6. PubMed ID: 9521419
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clonally expanded mitochondrial DNA mutations in epileptic individuals with mutated DNA polymerase gamma.
    Zsurka G; Baron M; Stewart JD; Kornblum C; Bös M; Sassen R; Taylor RW; Elger CE; Chinnery PF; Kunz WS
    J Neuropathol Exp Neurol; 2008 Sep; 67(9):857-66. PubMed ID: 18716558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors.
    Máximo V; Soares P; Lima J; Cameselle-Teijeiro J; Sobrinho-Simões M
    Am J Pathol; 2002 May; 160(5):1857-65. PubMed ID: 12000737
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Similar patterns of clonally expanded somatic mtDNA mutations in the colon of heterozygous mtDNA mutator mice and ageing humans.
    Baines HL; Stewart JB; Stamp C; Zupanic A; Kirkwood TB; Larsson NG; Turnbull DM; Greaves LC
    Mech Ageing Dev; 2014 Jul; 139():22-30. PubMed ID: 24915468
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Detection and quantification of the age-related point mutation A189G in the human mitochondrial DNA.
    Thèves C; Keyser-Tracqui C; Crubézy E; Salles JP; Ludes B; Telmon N
    J Forensic Sci; 2006 Jul; 51(4):865-73. PubMed ID: 16882231
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial DNA mutations and oxidative damage in aging and diseases: an emerging paradigm of gerontology and medicine.
    Wei YH
    Proc Natl Sci Counc Repub China B; 1998 Apr; 22(2):55-67. PubMed ID: 9615468
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication.
    Michikawa Y; Mazzucchelli F; Bresolin N; Scarlato G; Attardi G
    Science; 1999 Oct; 286(5440):774-9. PubMed ID: 10531063
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism?
    Chinnery PF; Samuels DC; Elson J; Turnbull DM
    Lancet; 2002 Oct; 360(9342):1323-5. PubMed ID: 12414225
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantitative allele-specific PCR: demonstration of age-associated accumulation in human tissues of the A-->G mutation at nucleotide 3243 in mitochondrial DNA.
    Liu VW; Zhang C; Linnane AW; Nagley P
    Hum Mutat; 1997; 9(3):265-71. PubMed ID: 9090530
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.