169 related articles for article (PubMed ID: 11948421)
1. The mdm2 proto-oncogene sensitizes human medullary thyroid carcinoma cells to ionizing radiation.
Dilla T; Romero J; Sanstisteban P; Velasco JA
Oncogene; 2002 Apr; 21(15):2376-86. PubMed ID: 11948421
[TBL] [Abstract][Full Text] [Related]
2. The MDM2 oncoprotein promotes apoptosis in p53-deficient human medullary thyroid carcinoma cells.
Dilla T; Velasco JA; Medina DL; González-Palacios JF; Santisteban P
Endocrinology; 2000 Jan; 141(1):420-9. PubMed ID: 10614665
[TBL] [Abstract][Full Text] [Related]
3. Mdm2 inhibition of p53 induces E2F1 transactivation via p21.
Wunderlich M; Berberich SJ
Oncogene; 2002 Jun; 21(28):4414-21. PubMed ID: 12080472
[TBL] [Abstract][Full Text] [Related]
4. Adenovirus-mediated E2F-1 gene transfer inhibits MDM2 expression and efficiently induces apoptosis in MDM2-overexpressing tumor cells.
Yang HL; Dong YB; Elliott MJ; Liu TJ; Atienza C; Stilwell A; McMasters KM
Clin Cancer Res; 1999 Aug; 5(8):2242-50. PubMed ID: 10473112
[TBL] [Abstract][Full Text] [Related]
5. Induction of apoptosis in human esophageal cancer cells by sequential transfer of the wild-type p53 and E2F-1 genes: involvement of p53 accumulation via ARF-mediated MDM2 down-regulation.
Itoshima T; Fujiwara T; Waku T; Shao J; Kataoka M; Yarbrough WG; Liu TJ; Roth JA; Tanaka N; Kodama M
Clin Cancer Res; 2000 Jul; 6(7):2851-9. PubMed ID: 10914734
[TBL] [Abstract][Full Text] [Related]
6. Additive effect of adenovirus-mediated E2F-1 gene transfer and topoisomerase II inhibitors on apoptosis in human osteosarcoma cells.
Yang HL; Dong YB; Elliott MJ; Wong SL; McMasters KM
Cancer Gene Ther; 2001 Apr; 8(4):241-51. PubMed ID: 11393276
[TBL] [Abstract][Full Text] [Related]
7. E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines.
Kitagawa M; Aonuma M; Lee SH; Fukutake S; McCormick F
Oncogene; 2008 Sep; 27(40):5303-14. PubMed ID: 18521084
[TBL] [Abstract][Full Text] [Related]
8. E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis.
Rogoff HA; Pickering MT; Debatis ME; Jones S; Kowalik TF
Mol Cell Biol; 2002 Aug; 22(15):5308-18. PubMed ID: 12101227
[TBL] [Abstract][Full Text] [Related]
9. p14(ARF) regulates E2F activity.
Mason SL; Loughran O; La Thangue NB
Oncogene; 2002 Jun; 21(27):4220-30. PubMed ID: 12082609
[TBL] [Abstract][Full Text] [Related]
10. Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53.
Blattner C; Sparks A; Lane D
Mol Cell Biol; 1999 May; 19(5):3704-13. PubMed ID: 10207094
[TBL] [Abstract][Full Text] [Related]
11. The E2F-family proteins induce distinct cell cycle regulatory factors in p16-arrested, U343 astrocytoma cells.
Dirks PB; Rutka JT; Hubbard SL; Mondal S; Hamel PA
Oncogene; 1998 Aug; 17(7):867-76. PubMed ID: 9780003
[TBL] [Abstract][Full Text] [Related]
12. E2F-1 up-regulates c-Myc and p14(ARF) and induces apoptosis in colon cancer cells.
Elliott MJ; Dong YB; Yang H; McMasters KM
Clin Cancer Res; 2001 Nov; 7(11):3590-7. PubMed ID: 11705881
[TBL] [Abstract][Full Text] [Related]
13. E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2.
Kowalik TF; DeGregori J; Leone G; Jakoi L; Nevins JR
Cell Growth Differ; 1998 Feb; 9(2):113-8. PubMed ID: 9486847
[TBL] [Abstract][Full Text] [Related]
14. E2F activity is essential for survival of Myc-overexpressing human cancer cells.
Santoni-Rugiu E; Duro D; Farkas T; Mathiasen IS; Jäättelä M; Bartek J; Lukas J
Oncogene; 2002 Sep; 21(42):6498-509. PubMed ID: 12226753
[TBL] [Abstract][Full Text] [Related]
15. Regulation of the retinoblastoma-dependent Mdm2 and E2F-1 signaling pathways during neuronal apoptosis.
Trinh E; Boutillier AL; Loeffler JP
Mol Cell Neurosci; 2001 Feb; 17(2):342-53. PubMed ID: 11178871
[TBL] [Abstract][Full Text] [Related]
16. Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1-mediated apoptosis in human esophageal cancer cells.
Yang HL; Dong YB; Elliott MJ; Liu TJ; McMasters KM
Clin Cancer Res; 2000 Apr; 6(4):1579-89. PubMed ID: 10778992
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of the E2F-1/p53/Bax pathway by tauroursodeoxycholic acid in amyloid beta-peptide-induced apoptosis of PC12 cells.
Ramalho RM; Ribeiro PS; Solá S; Castro RE; Steer CJ; Rodrigues CM
J Neurochem; 2004 Aug; 90(3):567-75. PubMed ID: 15255934
[TBL] [Abstract][Full Text] [Related]
18. Overexpression of E2F1 in glioma-derived cell lines induces a p53-independent apoptosis that is further enhanced by ionizing radiation.
Shu HK; Julin CM; Furman F; Yount GL; Haas-Kogan D; Israel MA
Neuro Oncol; 2000 Jan; 2(1):16-21. PubMed ID: 11302249
[TBL] [Abstract][Full Text] [Related]
19. Vitamin E succinate inhibits proliferation of BT-20 human breast cancer cells: increased binding of cyclin A negatively regulates E2F transactivation activity.
Turley JM; Ruscetti FW; Kim SJ; Fu T; Gou FV; Birchenall-Roberts MC
Cancer Res; 1997 Jul; 57(13):2668-75. PubMed ID: 9205075
[TBL] [Abstract][Full Text] [Related]
20. The MDM2 RING finger is required for cell cycle-dependent regulation of its protein expression.
Gu L; Ying H; Zheng H; Murray SA; Xiao ZX
FEBS Lett; 2003 Jun; 544(1-3):218-22. PubMed ID: 12782320
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]