BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

474 related articles for article (PubMed ID: 11950276)

  • 1. Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.
    Fagan AM; Watson M; Parsadanian M; Bales KR; Paul SM; Holtzman DM
    Neurobiol Dis; 2002 Apr; 9(3):305-18. PubMed ID: 11950276
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology.
    Baum L; Chen L; Ng HK; Pang CP
    Microsc Res Tech; 2000 Aug; 50(4):278-81. PubMed ID: 10936880
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.
    Holtzman DM; Fagan AM; Mackey B; Tenkova T; Sartorius L; Paul SM; Bales K; Ashe KH; Irizarry MC; Hyman BT
    Ann Neurol; 2000 Jun; 47(6):739-47. PubMed ID: 10852539
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease.
    Dodart JC; Marr RA; Koistinaho M; Gregersen BM; Malkani S; Verma IM; Paul SM
    Proc Natl Acad Sci U S A; 2005 Jan; 102(4):1211-6. PubMed ID: 15657137
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits.
    Yao J; Petanceska SS; Montine TJ; Holtzman DM; Schmidt SD; Parker CA; Callahan MJ; Lipinski WJ; Bisgaier CL; Turner BA; Nixon RA; Martins RN; Ouimet C; Smith JD; Davies P; Laska E; Ehrlich ME; Walker LC; Mathews PM; Gandy S
    J Neurochem; 2004 Aug; 90(4):1011-8. PubMed ID: 15287908
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T; Kiliaan AJ; Kadish I
    Neurobiol Dis; 2006 Sep; 23(3):653-62. PubMed ID: 16829076
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade.
    Dolev I; Michaelson DM
    Proc Natl Acad Sci U S A; 2004 Sep; 101(38):13909-14. PubMed ID: 15365176
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.
    Aleshkov S; Abraham CR; Zannis VI
    Biochemistry; 1997 Aug; 36(34):10571-80. PubMed ID: 9265639
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-beta deposition in vivo.
    Fagan AM; Holtzman DM
    Microsc Res Tech; 2000 Aug; 50(4):297-304. PubMed ID: 10936884
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ApoE isoform-specific effects on LTP: blockade by oligomeric amyloid-beta1-42.
    Trommer BL; Shah C; Yun SH; Gamkrelidze G; Pasternak ES; Stine WB; Manelli A; Sullivan P; Pasternak JF; LaDu MJ
    Neurobiol Dis; 2005 Feb; 18(1):75-82. PubMed ID: 15649697
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intraneuronal amyloid-beta plays a role in mediating the synergistic pathological effects of apoE4 and environmental stimulation.
    Levi O; Dolev I; Belinson H; Michaelson DM
    J Neurochem; 2007 Nov; 103(3):1031-40. PubMed ID: 17666042
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Apolipoprotein E co-localizes with newly formed amyloid beta-protein (Abeta) deposits lacking immunoreactivity against N-terminal epitopes of Abeta in a genotype-dependent manner.
    Thal DR; Capetillo-Zarate E; Schultz C; Rüb U; Saido TC; Yamaguchi H; Haass C; Griffin WS; Del Tredici K; Braak H; Ghebremedhin E
    Acta Neuropathol; 2005 Nov; 110(5):459-71. PubMed ID: 16195918
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation.
    Nilsson LN; Arendash GW; Leighty RE; Costa DA; Low MA; Garcia MF; Cracciolo JR; Rojiani A; Wu X; Bales KR; Paul SM; Potter H
    Neurobiol Aging; 2004 Oct; 25(9):1153-67. PubMed ID: 15312961
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A transgenic rat model of Alzheimer's disease with extracellular Abeta deposition.
    Flood DG; Lin YG; Lang DM; Trusko SP; Hirsch JD; Savage MJ; Scott RW; Howland DS
    Neurobiol Aging; 2009 Jul; 30(7):1078-90. PubMed ID: 18053619
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An apolipoprotein E-based therapeutic improves outcome and reduces Alzheimer's disease pathology following closed head injury: evidence of pharmacogenomic interaction.
    Wang H; Durham L; Dawson H; Song P; Warner DS; Sullivan PM; Vitek MP; Laskowitz DT
    Neuroscience; 2007 Feb; 144(4):1324-33. PubMed ID: 17187933
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Independent effects of APOE on cholesterol metabolism and brain Abeta levels in an Alzheimer disease mouse model.
    Mann KM; Thorngate FE; Katoh-Fukui Y; Hamanaka H; Williams DL; Fujita S; Lamb BT
    Hum Mol Genet; 2004 Sep; 13(17):1959-68. PubMed ID: 15229191
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isoform-specific effect of apolipoprotein E on endocytosis of beta-amyloid in cultures of neuroblastoma cells.
    Yamauchi K; Tozuka M; Hidaka H; Nakabayashi T; Sugano M; Katsuyama T
    Ann Clin Lab Sci; 2002; 32(1):65-74. PubMed ID: 11848621
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E.
    Fan J; Donkin J; Wellington C
    Biofactors; 2009; 35(3):239-48. PubMed ID: 19472365
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inflammation occurs early during the Abeta deposition process in TgCRND8 mice.
    Dudal S; Krzywkowski P; Paquette J; Morissette C; Lacombe D; Tremblay P; Gervais F
    Neurobiol Aging; 2004 Aug; 25(7):861-71. PubMed ID: 15212840
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Occurrence and co-localization of amyloid beta-protein and apolipoprotein E in perivascular drainage channels of wild-type and APP-transgenic mice.
    Thal DR; Larionov S; Abramowski D; Wiederhold KH; Van Dooren T; Yamaguchi H; Haass C; Van Leuven F; Staufenbiel M; Capetillo-Zarate E
    Neurobiol Aging; 2007 Aug; 28(8):1221-30. PubMed ID: 16815595
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.