191 related articles for article (PubMed ID: 11950795)
1. Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen.
Desai PB; Nallani SC; Sane RS; Moore LB; Goodwin BJ; Buckley DJ; Buckley AR
Drug Metab Dispos; 2002 May; 30(5):608-12. PubMed ID: 11950795
[TBL] [Abstract][Full Text] [Related]
2. Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate.
Nallani SC; Glauser TA; Hariparsad N; Setchell K; Buckley DJ; Buckley AR; Desai PB
Epilepsia; 2003 Dec; 44(12):1521-8. PubMed ID: 14636322
[TBL] [Abstract][Full Text] [Related]
3. Differences in the induction of cytochrome P450 3A4 by taxane anticancer drugs, docetaxel and paclitaxel, assessed employing primary human hepatocytes.
Nallani SC; Goodwin B; Buckley AR; Buckley DJ; Desai PB
Cancer Chemother Pharmacol; 2004 Sep; 54(3):219-29. PubMed ID: 15175893
[TBL] [Abstract][Full Text] [Related]
4. Induction of CYP3A4 by efavirenz in primary human hepatocytes: comparison with rifampin and phenobarbital.
Hariparsad N; Nallani SC; Sane RS; Buckley DJ; Buckley AR; Desai PB
J Clin Pharmacol; 2004 Nov; 44(11):1273-81. PubMed ID: 15496645
[TBL] [Abstract][Full Text] [Related]
5. Role of human pregnane X receptor in tamoxifen- and 4-hydroxytamoxifen-mediated CYP3A4 induction in primary human hepatocytes and LS174T cells.
Sane RS; Buckley DJ; Buckley AR; Nallani SC; Desai PB
Drug Metab Dispos; 2008 May; 36(5):946-54. PubMed ID: 18299335
[TBL] [Abstract][Full Text] [Related]
6. Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes.
Drocourt L; Pascussi JM; Assenat E; Fabre JM; Maurel P; Vilarem MJ
Drug Metab Dispos; 2001 Oct; 29(10):1325-31. PubMed ID: 11560876
[TBL] [Abstract][Full Text] [Related]
7. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
8. Induction of CYP3A4 by 1 alpha,25-dihydroxyvitamin D3 is human cell line-specific and is unlikely to involve pregnane X receptor.
Schmiedlin-Ren P; Thummel KE; Fisher JM; Paine MF; Watkins PB
Drug Metab Dispos; 2001 Nov; 29(11):1446-53. PubMed ID: 11602520
[TBL] [Abstract][Full Text] [Related]
9. Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators.
Pascussi JM; Drocourt L; Fabre JM; Maurel P; Vilarem MJ
Mol Pharmacol; 2000 Aug; 58(2):361-72. PubMed ID: 10908304
[TBL] [Abstract][Full Text] [Related]
10. The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module.
Goodwin B; Hodgson E; Liddle C
Mol Pharmacol; 1999 Dec; 56(6):1329-39. PubMed ID: 10570062
[TBL] [Abstract][Full Text] [Related]
11. Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.
Pascussi JM; Drocourt L; Gerbal-Chaloin S; Fabre JM; Maurel P; Vilarem MJ
Eur J Biochem; 2001 Dec; 268(24):6346-58. PubMed ID: 11737189
[TBL] [Abstract][Full Text] [Related]
12. A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.
Raucy J; Warfe L; Yueh MF; Allen SW
J Pharmacol Exp Ther; 2002 Oct; 303(1):412-23. PubMed ID: 12235278
[TBL] [Abstract][Full Text] [Related]
13. Avasimibe induces CYP3A4 and multiple drug resistance protein 1 gene expression through activation of the pregnane X receptor.
Sahi J; Milad MA; Zheng X; Rose KA; Wang H; Stilgenbauer L; Gilbert D; Jolley S; Stern RH; LeCluyse EL
J Pharmacol Exp Ther; 2003 Sep; 306(3):1027-34. PubMed ID: 12766253
[TBL] [Abstract][Full Text] [Related]
14. CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.
Luo G; Cunningham M; Kim S; Burn T; Lin J; Sinz M; Hamilton G; Rizzo C; Jolley S; Gilbert D; Downey A; Mudra D; Graham R; Carroll K; Xie J; Madan A; Parkinson A; Christ D; Selling B; LeCluyse E; Gan LS
Drug Metab Dispos; 2002 Jul; 30(7):795-804. PubMed ID: 12065438
[TBL] [Abstract][Full Text] [Related]
15. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
16. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
Wang H; Faucette SR; Gilbert D; Jolley SL; Sueyoshi T; Negishi M; LeCluyse EL
Drug Metab Dispos; 2003 May; 31(5):620-30. PubMed ID: 12695351
[TBL] [Abstract][Full Text] [Related]
17. Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.
Yang J; Yan B
Toxicol Sci; 2007 Jan; 95(1):13-22. PubMed ID: 17003103
[TBL] [Abstract][Full Text] [Related]
18. Identification of new human pregnane X receptor ligands among pesticides using a stable reporter cell system.
Lemaire G; Mnif W; Pascussi JM; Pillon A; Rabenoelina F; Fenet H; Gomez E; Casellas C; Nicolas JC; Cavaillès V; Duchesne MJ; Balaguer P
Toxicol Sci; 2006 Jun; 91(2):501-9. PubMed ID: 16565514
[TBL] [Abstract][Full Text] [Related]
19. Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor.
Harmsen S; Meijerman I; Beijnen JH; Schellens JH
Cancer Chemother Pharmacol; 2009 Jun; 64(1):35-43. PubMed ID: 18839173
[TBL] [Abstract][Full Text] [Related]
20. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
