BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 11952335)

  • 1. Sulfhydryl binding and topoisomerase inhibition by PCB metabolites.
    Srinivasan A; Robertson LW; Ludewig G
    Chem Res Toxicol; 2002 Apr; 15(4):497-505. PubMed ID: 11952335
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites.
    Srinivasan A; Lehmler HJ; Robertson LW; Ludewig G
    Toxicol Sci; 2001 Mar; 60(1):92-102. PubMed ID: 11222876
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polychlorinated biphenyl quinone metabolites lead to oxidative stress in HepG2 cells and the protective role of dihydrolipoic acid.
    Liu J; Song E; Liu L; Ma X; Tian X; Dong H; Song Y
    Toxicol In Vitro; 2012 Sep; 26(6):841-8. PubMed ID: 22580158
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Polychlorinated biphenyl quinone metabolites poison human topoisomerase IIalpha: altering enzyme function by blocking the N-terminal protein gate.
    Bender RP; Lehmler HJ; Robertson LW; Ludewig G; Osheroff N
    Biochemistry; 2006 Aug; 45(33):10140-52. PubMed ID: 16906772
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytotoxic effects of polychlorinated biphenyl hydroquinone metabolites in rat hepatocytes.
    Chan K; Lehmler HJ; Sivagnanam M; Feng CY; Robertson L; O'Brien PJ
    J Appl Toxicol; 2010 Mar; 30(2):163-71. PubMed ID: 19830680
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen receptors in hepatic and mammary cells.
    Machala M; Bláha L; Lehmler HJ; Plísková M; Májková Z; Kapplová P; Sovadinová I; Vondrácek J; Malmberg T; Robertson LW
    Chem Res Toxicol; 2004 Mar; 17(3):340-7. PubMed ID: 15025504
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oxidative DNA adducts after Cu(2+)-mediated activation of dihydroxy PCBs: role of reactive oxygen species.
    Spencer WA; Lehmler HJ; Robertson LW; Gupta RC
    Free Radic Biol Med; 2009 May; 46(10):1346-52. PubMed ID: 19233261
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chlorination increases the persistence of semiquinone free radicals derived from polychlorinated biphenyl hydroquinones and quinones.
    Song Y; Buettner GR; Parkin S; Wagner BA; Robertson LW; Lehmler HJ
    J Org Chem; 2008 Nov; 73(21):8296-304. PubMed ID: 18839991
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolic activation of PCBs to quinones: reactivity toward nitrogen and sulfur nucleophiles and influence of superoxide dismutase.
    Amaro AR; Oakley GG; Bauer U; Spielmann HP; Robertson LW
    Chem Res Toxicol; 1996; 9(3):623-9. PubMed ID: 8728508
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Polychlorinated biphenyls and their different level metabolites as inhibitors of glutathione S-transferase isoenzymes.
    Tian X; Song E; Pi R; Zhu X; Liu L; Ma X; Dong H; Liu J; Song Y
    Chem Biol Interact; 2012 Jun; 198(1-3):1-8. PubMed ID: 22542669
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization and quantitative analysis of DNA adducts formed from lower chlorinated PCB-derived quinones.
    Zhao S; Narang A; Ding X; Eadon G
    Chem Res Toxicol; 2004 Apr; 17(4):502-11. PubMed ID: 15089092
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells.
    Dreiem A; Rykken S; Lehmler HJ; Robertson LW; Fonnum F
    Toxicol Appl Pharmacol; 2009 Oct; 240(2):306-13. PubMed ID: 19631230
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites.
    Xie W; Wang K; Robertson LW; Ludewig G
    Environ Int; 2010 Nov; 36(8):950-61. PubMed ID: 20129669
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs): implications for PCB-induced oxidative stress in breast cancer.
    Oakley GG; Devanaboyina U; Robertson LW; Gupta RC
    Chem Res Toxicol; 1996 Dec; 9(8):1285-92. PubMed ID: 8951230
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxidative metabolism of combretastatin A-1 produces quinone intermediates with the potential to bind to nucleophiles and to enhance oxidative stress via free radicals.
    Folkes LK; Christlieb M; Madej E; Stratford MR; Wardman P
    Chem Res Toxicol; 2007 Dec; 20(12):1885-94. PubMed ID: 17941699
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Breaking the dogma: PCB-derived semiquinone free radicals do not form covalent adducts with DNA, GSH, and amino acids.
    Wangpradit O; Rahaman A; Mariappan SV; Buettner GR; Robertson LW; Luthe G
    Environ Sci Pollut Res Int; 2016 Feb; 23(3):2138-47. PubMed ID: 26396011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nonenzymatic displacement of chlorine and formation of free radicals upon the reaction of glutathione with PCB quinones.
    Song Y; Wagner BA; Witmer JR; Lehmler HJ; Buettner GR
    Proc Natl Acad Sci U S A; 2009 Jun; 106(24):9725-30. PubMed ID: 19497881
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thiols oxidation and covalent binding of BSA by cyclolignanic quinones are enhanced by the magnesium cation.
    Alegria AE; Sanchez-Cruz P; Kumar A; Garcia C; Gonzalez FA; Orellano A; Zayas B; Gordaliza M
    Free Radic Res; 2008 Jan; 42(1):70-81. PubMed ID: 18324525
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene.
    Hutt AM; Kalf GF
    Environ Health Perspect; 1996 Dec; 104 Suppl 6(Suppl 6):1265-9. PubMed ID: 9118903
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Semiquinone radicals from oxygenated polychlorinated biphenyls: electron paramagnetic resonance studies.
    Song Y; Wagner BA; Lehmler HJ; Buettner GR
    Chem Res Toxicol; 2008 Jul; 21(7):1359-67. PubMed ID: 18549251
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.