These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 11956193)

  • 41. Products resulting from cleavage of the interglobular domain of aggrecan in samples of synovial fluid collected from dogs with early- and late-stage osteoarthritis.
    Innes JF; Little CB; Hughes CE; Caterson B
    Am J Vet Res; 2005 Oct; 66(10):1679-85. PubMed ID: 16273897
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Analysis of ADAMTS4 and MT4-MMP indicates that both are involved in aggrecanolysis in interleukin-1-treated bovine cartilage.
    Patwari P; Gao G; Lee JH; Grodzinsky AJ; Sandy JD
    Osteoarthritis Cartilage; 2005 Apr; 13(4):269-77. PubMed ID: 15780640
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Development of a novel clinical biomarker assay to detect and quantify aggrecanase-generated aggrecan fragments in human synovial fluid, serum and urine.
    Swearingen CA; Carpenter JW; Siegel R; Brittain IJ; Dotzlaf J; Durham TB; Toth JL; Laska DA; Marimuthu J; Liu C; Brown DP; Carter QL; Wiley MR; Duffin KL; Mitchell PG; Thirunavukkarasu K
    Osteoarthritis Cartilage; 2010 Sep; 18(9):1150-8. PubMed ID: 20633682
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms.
    Wilkinson DJ; Wang H; Habgood A; Lamb HK; Thompson P; Hawkins AR; Désilets A; Leduc R; Steinmetzer T; Hammami M; Lee MS; Craik CS; Watson S; Lin H; Milner JM; Rowan AD
    Arthritis Rheumatol; 2017 Aug; 69(8):1601-1611. PubMed ID: 28464560
    [TBL] [Abstract][Full Text] [Related]  

  • 45. IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage.
    Flannery CR; Little CB; Hughes CE; Curtis CL; Caterson B; Jones SA
    Matrix Biol; 2000 Nov; 19(6):549-53. PubMed ID: 11068209
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Expression and regulation of aggrecanase in arthritis: the role of TGF-beta.
    Yamanishi Y; Boyle DL; Clark M; Maki RA; Tortorella MD; Arner EC; Firestein GS
    J Immunol; 2002 Feb; 168(3):1405-12. PubMed ID: 11801682
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Induction of aggrecanase 1 (ADAM-TS4) by interleukin-1 occurs through activation of constitutively produced protein.
    Pratta MA; Scherle PA; Yang G; Liu RQ; Newton RC
    Arthritis Rheum; 2003 Jan; 48(1):119-33. PubMed ID: 12528112
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Development and characterization of a highly specific and sensitive sandwich ELISA for detection of aggrecanase-generated aggrecan fragments.
    Pratta MA; Su JL; Leesnitzer MA; Struglics A; Larsson S; Lohmander LS; Kumar S
    Osteoarthritis Cartilage; 2006 Jul; 14(7):702-13. PubMed ID: 16549371
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4).
    Tortorella MD; Pratta M; Liu RQ; Austin J; Ross OH; Abbaszade I; Burn T; Arner E
    J Biol Chem; 2000 Jun; 275(24):18566-73. PubMed ID: 10751421
    [TBL] [Abstract][Full Text] [Related]  

  • 50. The effect of protease inhibitors on the induction of osteoarthritis-related biomarkers in bovine full-depth cartilage explants.
    He Y; Zheng Q; Jiang M; Sun S; Christiansen TG; Kassem M; Karsdal MA; Bay-Jensen AC
    PLoS One; 2015; 10(4):e0122700. PubMed ID: 25909781
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Aggrecan protects cartilage collagen from proteolytic cleavage.
    Pratta MA; Yao W; Decicco C; Tortorella MD; Liu RQ; Copeland RA; Magolda R; Newton RC; Trzaskos JM; Arner EC
    J Biol Chem; 2003 Nov; 278(46):45539-45. PubMed ID: 12890681
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro.
    Hughes CE; Caterson B; Fosang AJ; Roughley PJ; Mort JS
    Biochem J; 1995 Feb; 305 ( Pt 3)(Pt 3):799-804. PubMed ID: 7531436
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Aggrecan degradation in human intervertebral disc and articular cartilage.
    Sztrolovics R; Alini M; Roughley PJ; Mort JS
    Biochem J; 1997 Aug; 326 ( Pt 1)(Pt 1):235-41. PubMed ID: 9337874
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration.
    Janusz MJ; Little CB; King LE; Hookfin EB; Brown KK; Heitmeyer SA; Caterson B; Poole AR; Taiwo YO
    Osteoarthritis Cartilage; 2004 Sep; 12(9):720-8. PubMed ID: 15325638
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic cartilage.
    Naito S; Shiomi T; Okada A; Kimura T; Chijiiwa M; Fujita Y; Yatabe T; Komiya K; Enomoto H; Fujikawa K; Okada Y
    Pathol Int; 2007 Nov; 57(11):703-11. PubMed ID: 17922681
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Changes in joint cartilage aggrecan after knee injury and in osteoarthritis.
    Lohmander LS; Ionescu M; Jugessur H; Poole AR
    Arthritis Rheum; 1999 Mar; 42(3):534-44. PubMed ID: 10088777
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Effect of Phellodendron amurense in protecting human osteoarthritic cartilage and chondrocytes.
    Kim JH; Huh JE; Baek YH; Lee JD; Choi DY; Park DS
    J Ethnopharmacol; 2011 Mar; 134(2):234-42. PubMed ID: 21182922
    [TBL] [Abstract][Full Text] [Related]  

  • 58. TIMP-3 inhibition of ADAMTS-4 (Aggrecanase-1) is modulated by interactions between aggrecan and the C-terminal domain of ADAMTS-4.
    Wayne GJ; Deng SJ; Amour A; Borman S; Matico R; Carter HL; Murphy G
    J Biol Chem; 2007 Jul; 282(29):20991-8. PubMed ID: 17470431
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Inhibition of ADAMTS4 (aggrecanase-1) by tissue inhibitors of metalloproteinases (TIMP-1, 2, 3 and 4).
    Hashimoto G; Aoki T; Nakamura H; Tanzawa K; Okada Y
    FEBS Lett; 2001 Apr; 494(3):192-5. PubMed ID: 11311239
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent.
    Fosang AJ; Last K; Maciewicz RA
    J Clin Invest; 1996 Nov; 98(10):2292-9. PubMed ID: 8941646
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.