BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

313 related articles for article (PubMed ID: 11956242)

  • 1. Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1.
    Chen HC; Smith SJ; Ladha Z; Jensen DR; Ferreira LD; Pulawa LK; McGuire JG; Pitas RE; Eckel RH; Farese RV
    J Clin Invest; 2002 Apr; 109(8):1049-55. PubMed ID: 11956242
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deficiency of acyl coenzyme a:diacylglycerol acyltransferase 1 increases leptin sensitivity in murine obesity models.
    Chen HC; Ladha Z; Farese RV
    Endocrinology; 2002 Aug; 143(8):2893-8. PubMed ID: 12130553
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice.
    Chen HC; Farese RV
    Arterioscler Thromb Vasc Biol; 2005 Mar; 25(3):482-6. PubMed ID: 15569818
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of DGAT2 in white adipose tissue is regulated by central leptin action.
    Suzuki R; Tobe K; Aoyama M; Sakamoto K; Ohsugi M; Kamei N; Nemoto S; Inoue A; Ito Y; Uchida S; Hara K; Yamauchi T; Kubota N; Terauchi Y; Kadowaki T
    J Biol Chem; 2005 Feb; 280(5):3331-7. PubMed ID: 15550388
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Obesity resistance and enhanced glucose metabolism in mice transplanted with white adipose tissue lacking acyl CoA:diacylglycerol acyltransferase 1.
    Chen HC; Jensen DR; Myers HM; Eckel RH; Farese RV
    J Clin Invest; 2003 Jun; 111(11):1715-22. PubMed ID: 12782674
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl coenzyme a:diacylglycerol acyltransferase 1 in white adipose tissue.
    Chen HC; Stone SJ; Zhou P; Buhman KK; Farese RV
    Diabetes; 2002 Nov; 51(11):3189-95. PubMed ID: 12401709
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat.
    Smith SJ; Cases S; Jensen DR; Chen HC; Sande E; Tow B; Sanan DA; Raber J; Eckel RH; Farese RV
    Nat Genet; 2000 May; 25(1):87-90. PubMed ID: 10802663
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Concerted elevation of acyl-coenzyme A:diacylglycerol acyltransferase (DGAT) activity through independent stimulation of mRNA expression of DGAT1 and DGAT2 by carbohydrate and insulin.
    Meegalla RL; Billheimer JT; Cheng D
    Biochem Biophys Res Commun; 2002 Nov; 298(3):317-23. PubMed ID: 12413942
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of energy expenditure at different ambient temperatures in mice lacking DGAT1.
    Chen HC; Ladha Z; Smith SJ; Farese RV
    Am J Physiol Endocrinol Metab; 2003 Jan; 284(1):E213-8. PubMed ID: 12388146
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) with small molecule inhibitors for the treatment of metabolic diseases.
    Cao J; Zhou Y; Peng H; Huang X; Stahler S; Suri V; Qadri A; Gareski T; Jones J; Hahm S; Perreault M; McKew J; Shi M; Xu X; Tobin JF; Gimeno RE
    J Biol Chem; 2011 Dec; 286(48):41838-41851. PubMed ID: 21990351
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1.
    Chen HC; Rao M; Sajan MP; Standaert M; Kanoh Y; Miura A; Farese RV; Farese RV
    Diabetes; 2004 Jun; 53(6):1445-51. PubMed ID: 15161747
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands.
    Chen HC; Smith SJ; Tow B; Elias PM; Farese RV
    J Clin Invest; 2002 Jan; 109(2):175-81. PubMed ID: 11805129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes.
    Chitraju C; Walther TC; Farese RV
    J Lipid Res; 2019 Jun; 60(6):1112-1120. PubMed ID: 30936184
    [TBL] [Abstract][Full Text] [Related]  

  • 14. JTT-553, a novel Acyl CoA:diacylglycerol acyltransferase (DGAT) 1 inhibitor, improves glucose metabolism in diet-induced obesity and genetic T2DM mice.
    Tomimoto D; Okuma C; Ishii Y; Kobayashi A; Ohta T; Kakutani M; Imanaka T; Ogawa N
    J Pharmacol Sci; 2015 Sep; 129(1):51-8. PubMed ID: 26354408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of DGAT1 deficiency on energy and glucose metabolism are independent of adiponectin.
    Streeper RS; Koliwad SK; Villanueva CJ; Farese RV
    Am J Physiol Endocrinol Metab; 2006 Aug; 291(2):E388-94. PubMed ID: 16595853
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.
    Malloy VL; Perrone CE; Mattocks DA; Ables GP; Caliendo NS; Orentreich DS; Orentreich N
    Metabolism; 2013 Nov; 62(11):1651-61. PubMed ID: 23928105
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel coenzyme A:diacylglycerol acyltransferase 1 inhibitor stimulates lipid metabolism in muscle and lowers weight in animal models of obesity.
    Yamamoto T; Yamaguchi H; Miki H; Kitamura S; Nakada Y; Aicher TD; Pratt SA; Kato K
    Eur J Pharmacol; 2011 Jan; 650(2-3):663-72. PubMed ID: 21034741
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhancing energy and glucose metabolism by disrupting triglyceride synthesis: Lessons from mice lacking DGAT1.
    Chen HC
    Nutr Metab (Lond); 2006 Jan; 3():10. PubMed ID: 16448557
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DGAT and triglyceride synthesis: a new target for obesity treatment?
    Chen HC; Farese RV
    Trends Cardiovasc Med; 2000 Jul; 10(5):188-92. PubMed ID: 11282293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice.
    Yu XX; Murray SF; Pandey SK; Booten SL; Bao D; Song XZ; Kelly S; Chen S; McKay R; Monia BP; Bhanot S
    Hepatology; 2005 Aug; 42(2):362-71. PubMed ID: 16001399
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.