206 related articles for article (PubMed ID: 11956513)
1. Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.
Nakamura T; Sakaeda T; Horinouchi M; Tamura T; Aoyama N; Shirakawa T; Matsuo M; Kasuga M; Okumura K
Clin Pharmacol Ther; 2002 Apr; 71(4):297-303. PubMed ID: 11956513
[TBL] [Abstract][Full Text] [Related]
2. Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects.
Moriya Y; Nakamura T; Horinouchi M; Sakaeda T; Tamura T; Aoyama N; Shirakawa T; Gotoh A; Fujimoto S; Matsuo M; Kasuga M; Okumura K
Biol Pharm Bull; 2002 Oct; 25(10):1356-9. PubMed ID: 12392094
[TBL] [Abstract][Full Text] [Related]
3. C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation.
Goto M; Masuda S; Saito H; Uemoto S; Kiuchi T; Tanaka K; Inui K
Pharmacogenetics; 2002 Aug; 12(6):451-7. PubMed ID: 12172213
[TBL] [Abstract][Full Text] [Related]
4. Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas.
Nakamura T; Sakaeda T; Ohmoto N; Tamura T; Aoyama N; Shirakawa T; Kamigaki T; Nakamura T; Kim KI; Kim SR; Kuroda Y; Matsuo M; Kasuga M; Okumura K
Drug Metab Dispos; 2002 Jan; 30(1):4-6. PubMed ID: 11744604
[TBL] [Abstract][Full Text] [Related]
5. Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
Becquemont L; Glaeser H; Drescher S; Hitzl M; Simon N; Murdter TE; Heinkele G; Hofmann U; Schaefer C; Burk O; Verstuyft C; Eichelbaum M; Fromm MF
Clin Pharmacol Ther; 2006 May; 79(5):449-60. PubMed ID: 16678547
[TBL] [Abstract][Full Text] [Related]
6. MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects.
Sakaeda T; Nakamura T; Horinouchi M; Kakumoto M; Ohmoto N; Sakai T; Morita Y; Tamura T; Aoyama N; Hirai M; Kasuga M; Okumura K
Pharm Res; 2001 Oct; 18(10):1400-4. PubMed ID: 11697464
[TBL] [Abstract][Full Text] [Related]
7. Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens.
von Richter O; Burk O; Fromm MF; Thon KP; Eichelbaum M; Kivistö KT
Clin Pharmacol Ther; 2004 Mar; 75(3):172-83. PubMed ID: 15001968
[TBL] [Abstract][Full Text] [Related]
8. Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Cummins CL; Mangravite LM; Benet LZ
Pharm Res; 2001 Aug; 18(8):1102-9. PubMed ID: 11587480
[TBL] [Abstract][Full Text] [Related]
9. MDR1 genotype-related duodenal absorption rate of digoxin in healthy Japanese subjects.
Morita Y; Sakaeda T; Horinouchi M; Nakamura T; Kuroda K; Miki I; Yoshimura K; Sakai T; Shirasaka D; Tamura T; Aoyama N; Kasuga M; Okumura K
Pharm Res; 2003 Apr; 20(4):552-6. PubMed ID: 12739761
[TBL] [Abstract][Full Text] [Related]
10. Preferential expression of a mutant allele of the amplified MDR1 (ABCB1) gene in drug-resistant variants of a human sarcoma.
Chen KG; Lacayo NJ; Durán GE; Wang Y; Bangs CD; Rea S; Kovacs M; Cherry AM; Brown JM; Sikic BI
Genes Chromosomes Cancer; 2002 Aug; 34(4):372-83. PubMed ID: 12112526
[TBL] [Abstract][Full Text] [Related]
11. Meta-analysis of the influence of MDR1 C3435T polymorphism on digoxin pharmacokinetics and MDR1 gene expression.
Chowbay B; Li H; David M; Cheung YB; Lee EJ
Br J Clin Pharmacol; 2005 Aug; 60(2):159-71. PubMed ID: 16042669
[TBL] [Abstract][Full Text] [Related]
12. St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4.
Dürr D; Stieger B; Kullak-Ublick GA; Rentsch KM; Steinert HC; Meier PJ; Fattinger K
Clin Pharmacol Ther; 2000 Dec; 68(6):598-604. PubMed ID: 11180019
[TBL] [Abstract][Full Text] [Related]
13. Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5.
Mouly SJ; Matheny C; Paine MF; Smith G; Lamba J; Lamba V; Pusek SN; Schuetz EG; Stewart PW; Watkins PB
Clin Pharmacol Ther; 2005 Dec; 78(6):605-18. PubMed ID: 16338276
[TBL] [Abstract][Full Text] [Related]
14. Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans.
Giessmann T; May K; Modess C; Wegner D; Hecker U; Zschiesche M; Dazert P; Grube M; Schroeder E; Warzok R; Cascorbi I; Kroemer HK; Siegmund W
Clin Pharmacol Ther; 2004 Sep; 76(3):192-200. PubMed ID: 15371980
[TBL] [Abstract][Full Text] [Related]
15. MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity.
Ameyaw MM; Regateiro F; Li T; Liu X; Tariq M; Mobarek A; Thornton N; Folayan GO; Githang'a J; Indalo A; Ofori-Adjei D; Price-Evans DA; McLeod HL
Pharmacogenetics; 2001 Apr; 11(3):217-21. PubMed ID: 11337937
[TBL] [Abstract][Full Text] [Related]
16. Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines.
Pfrunder A; Gutmann H; Beglinger C; Drewe J
J Pharm Pharmacol; 2003 Jan; 55(1):59-66. PubMed ID: 12625868
[TBL] [Abstract][Full Text] [Related]
17. The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.
Siegmund W; Ludwig K; Giessmann T; Dazert P; Schroeder E; Sperker B; Warzok R; Kroemer HK; Cascorbi I
Clin Pharmacol Ther; 2002 Nov; 72(5):572-83. PubMed ID: 12426521
[TBL] [Abstract][Full Text] [Related]
18. No influence of the MDR-1 C3435T polymorphism or a CYP3A4 promoter polymorphism (CYP3A4-V allele) on dose-adjusted cyclosporin A trough concentrations or rejection incidence in stable renal transplant recipients.
von Ahsen N; Richter M; Grupp C; Ringe B; Oellerich M; Armstrong VW
Clin Chem; 2001 Jun; 47(6):1048-52. PubMed ID: 11375290
[TBL] [Abstract][Full Text] [Related]
19. Localization and mRNA expression of CYP3A and P-glycoprotein in human duodenum as a function of age.
Fakhoury M; Litalien C; Medard Y; Cavé H; Ezzahir N; Peuchmaur M; Jacqz-Aigrain E
Drug Metab Dispos; 2005 Nov; 33(11):1603-7. PubMed ID: 16049125
[TBL] [Abstract][Full Text] [Related]
20. Initial dosage adjustment for oral administration of tacrolimus using the intestinal MDR1 level in living-donor liver transplant recipients.
Masuda S; Goto M; Okuda M; Ogura Y; Oike F; Kiuchi T; Tanaka K; Inui K
Transplant Proc; 2005 May; 37(4):1728-9. PubMed ID: 15919446
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]