107 related articles for article (PubMed ID: 11958989)
1. QSAR study on adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues using the hansch approach.
Srikanth K; Debnath B; Jha T
Bioorg Med Chem Lett; 2002 Mar; 12(6):899-902. PubMed ID: 11958989
[TBL] [Abstract][Full Text] [Related]
2. A CoMSIA study on the adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues.
Caballero J; Fernández M; González-Nilo FD
Bioorg Med Chem; 2008 May; 16(9):5103-8. PubMed ID: 18359230
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of 6,7-disubstituted 4-aminopyrido[2,3-d]pyrimidines as adenosine kinase inhibitors.
Perner RJ; Lee CH; Jiang M; Gu YG; Didomenico S; Bayburt EK; Alexander KM; Kohlhaas KL; Jarvis MF; Kowaluk EL; Bhagwat SS
Bioorg Med Chem Lett; 2005 Jun; 15(11):2803-7. PubMed ID: 15911258
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of novel ligands for the histamine H₄ receptor based on a pyrrolo[2,3-d]pyrimidine scaffold.
Gao LJ; Schwed JS; Weizel L; De Jonghe S; Stark H; Herdewijn P
Bioorg Med Chem Lett; 2013 Jan; 23(1):132-7. PubMed ID: 23218604
[TBL] [Abstract][Full Text] [Related]
5. Adenosine kinase inhibitors. 6. Synthesis, water solubility, and antinociceptive activity of 5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidines substituted at C4 with glycinamides and related compounds.
Bookser BC; Ugarkar BG; Matelich MC; Lemus RH; Allan M; Tsuchiya M; Nakane M; Nagahisa A; Wiesner JB; Erion MD
J Med Chem; 2005 Dec; 48(24):7808-20. PubMed ID: 16302820
[TBL] [Abstract][Full Text] [Related]
6. A TOPS-MODE approach to predict adenosine kinase inhibition.
González MP; Moldes del Carmen Terán M
Bioorg Med Chem Lett; 2004 Jun; 14(12):3077-9. PubMed ID: 15149648
[TBL] [Abstract][Full Text] [Related]
7. 4-amino-5-aryl-6-arylethynylpyrimidines: structure-activity relationships of non-nucleoside adenosine kinase inhibitors.
Matulenko MA; Paight ES; Frey RR; Gomtsyan A; DiDomenico S; Jiang M; Lee CH; Stewart AO; Yu H; Kohlhaas KL; Alexander KM; McGaraughty S; Mikusa J; Marsh KC; Muchmore SW; Jakob CL; Kowaluk EA; Jarvis MF; Bhagwat SS
Bioorg Med Chem; 2007 Feb; 15(4):1586-605. PubMed ID: 17197188
[TBL] [Abstract][Full Text] [Related]
8. Quantitative structure-activity relationship study of 5-iodo- and diaryl-analogues of tubercidin: inhibitors of adenosine kinase.
Singh P; Kumar R; Sharma BK
J Enzyme Inhib Med Chem; 2003 Oct; 18(5):395-402. PubMed ID: 14692505
[TBL] [Abstract][Full Text] [Related]
9. Structure-activity studies of 5-substituted pyridopyrimidines as adenosine kinase inhibitors.
Cowart M; Lee CH; Gfesser GA; Bayburt EK; Bhagwat SS; Stewart AO; Yu H; Kohlhaas KL; McGaraughty S; Wismer CT; Mikusa J; Zhu C; Alexander KM; Jarvis MF; Kowaluk EA
Bioorg Med Chem Lett; 2001 Jan; 11(1):83-6. PubMed ID: 11140740
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and activity of novel 5-substituted pyrrolo[2,3-d]pyrimidine analogues as pp60(c-Src) tyrosine kinase inhibitors.
Olgen S; Isgör YG; Coban T
Arch Pharm (Weinheim); 2008 Feb; 341(2):113-20. PubMed ID: 18214841
[TBL] [Abstract][Full Text] [Related]
11. Analgesic and anti-inflammatory effects of A-286501, a novel orally active adenosine kinase inhibitor.
Jarvis MF; Yu H; McGaraughty S; Wismer CT; Mikusa J; Zhu C; Chu K; Kohlhaas K; Cowart M; Lee CH; Stewart AO; Cox BF; Polakowski J; Kowaluk EA
Pain; 2002 Mar; 96(1-2):107-18. PubMed ID: 11932067
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of 3-arylpiperazinylalkylpyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as novel, potent, and selective alpha1-adrenoceptor ligands.
Patanè E; Pittalà V; Guerrera F; Salerno L; Romeo G; Siracusa MA; Russo F; Manetti F; Botta M; Mereghetti I; Cagnotto A; Mennini T
J Med Chem; 2005 Apr; 48(7):2420-31. PubMed ID: 15801833
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and anti-HIV-1 activity of 4-substituted-7-(2'-deoxy-2'-fluoro-4'-azido-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine analogues.
Guo X; Li Y; Tao L; Wang Q; Wang S; Hu W; Pan Z; Yang Q; Cui Y; Ge Z; Dong L; Yu X; An H; Song C; Chang J
Bioorg Med Chem Lett; 2011 Nov; 21(22):6770-2. PubMed ID: 21974951
[TBL] [Abstract][Full Text] [Related]
14. Molecular modeling study of CP-690550 derivatives as JAK3 kinase inhibitors through combined 3D-QSAR, molecular docking, and dynamics simulation techniques.
Wang JL; Cheng LP; Wang TC; Deng W; Wu FH
J Mol Graph Model; 2017 Mar; 72():178-186. PubMed ID: 28107751
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and antiviral evaluation of 2'-C-methyl analogues of 5-alkynyl- and 6-alkylfurano- and pyrrolo[2,3-d]pyrimidine ribonucleosides.
Januszczyk P; Fogt J; Boryski J; Izawa K; Onishi T; Neyts J; De Clercq E
Nucleosides Nucleotides Nucleic Acids; 2009 May; 28(5):713-23. PubMed ID: 20183611
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and properties of 7-substituted 7-deazapurine (pyrrolo[2,3-d]pyrimidine) 2'-deoxyribonucleosides.
Seela F; Peng X
Curr Protoc Nucleic Acid Chem; 2005 Jul; Chapter 1():Unit 1.10. PubMed ID: 18428932
[TBL] [Abstract][Full Text] [Related]
17. Exploration of potential EGFR inhibitors: a combination of pharmacophore-based virtual screening, atom-based 3D-QSAR and molecular docking analysis.
Sudha A; Srinivasan P; Rameshthangam P
J Recept Signal Transduct Res; 2015 Apr; 35(2):137-48. PubMed ID: 25069678
[TBL] [Abstract][Full Text] [Related]
18. ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse.
Jarvis MF; Yu H; Kohlhaas K; Alexander K; Lee CH; Jiang M; Bhagwat SS; Williams M; Kowaluk EA
J Pharmacol Exp Ther; 2000 Dec; 295(3):1156-64. PubMed ID: 11082453
[TBL] [Abstract][Full Text] [Related]
19. Discovery of 4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl)pyrido[2,3-d]pyrimidine, an orally active, non-nucleoside adenosine kinase inhibitor.
Lee CH; Jiang M; Cowart M; Gfesser G; Perner R; Kim KH; Gu YG; Williams M; Jarvis MF; Kowaluk EA; Stewart AO; Bhagwat SS
J Med Chem; 2001 Jun; 44(13):2133-8. PubMed ID: 11405650
[TBL] [Abstract][Full Text] [Related]
20. Cytotoxic and Apoptotic Effects of Novel Pyrrolo[2,3-d]Pyrimidine Derivatives Containing Urea Moieties on Cancer Cell Lines.
Kilic-Kurt Z; Bakar-Ates F; Karakas B; Kütük Ö
Anticancer Agents Med Chem; 2018; 18(9):1303-1312. PubMed ID: 29866023
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]